ECSP003605A - EDIBLE HOLOGRAPHIC PRODUCTS, PARTICULARLY PHARMACEUTICAL, AND METHODS AND APPARATUS FOR PRODUCING THEM - Google Patents
EDIBLE HOLOGRAPHIC PRODUCTS, PARTICULARLY PHARMACEUTICAL, AND METHODS AND APPARATUS FOR PRODUCING THEMInfo
- Publication number
- ECSP003605A ECSP003605A ECSP003605A ECSP003605A EC SP003605 A ECSP003605 A EC SP003605A EC SP003605 A ECSP003605 A EC SP003605A EC SP003605 A ECSP003605 A EC SP003605A
- Authority
- EC
- Ecuador
- Prior art keywords
- relief
- layer
- active substance
- pharmaceutically active
- micro
- Prior art date
Links
- 239000002552 dosage form Substances 0.000 abstract 4
- 239000013543 active substance Substances 0.000 abstract 3
- 239000011248 coating agent Substances 0.000 abstract 2
- 238000000576 coating method Methods 0.000 abstract 2
- 239000000463 material Substances 0.000 abstract 2
- 239000000654 additive Substances 0.000 abstract 1
- 239000000853 adhesive Substances 0.000 abstract 1
- 230000001070 adhesive effect Effects 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000003086 colorant Substances 0.000 abstract 1
- 238000001816 cooling Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 239000004014 plasticizer Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
- 230000000007 visual effect Effects 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
Abstract
Un producto comestible tal como una forma de dosificación unitaria de una sustancia farmacéuticamente activa incluye una capa de un material que puede recibir y retener una microrelieve de alta resolución que puede transmitir información. El microrelieve es termoformable, formando preferentemente de una solución acuosa de hpmc y/o HPC más un plastificante y un colorante. De cauerdo con la aplicación, pueden ser usados otros aditivos tales como reforzadores agentes tensoactivos y adhesivos. Los materiales son seleccionados y proporcionados para controlar el palidecimiento o la modificación del color de la imagen visual o efecto producido por el relieve, para indicar la exposición a un grado inaceptable de calor o humudad. La forma de dosificación puede estar constituida por la misma capa que contiene el relieve que lleva la sustancia farmacéuticamente activa. En una forma preferida, la capa es un recubrimiento exterior sobre un nucleo que contiene una sustancia farmacéuticamente activa. Las tabletas recubiertas están configuradas para resistir la formación de mellizos. Para producir tales formas de dosificación, el nucleo recubierto es transportado en coordinación con un molde o una capa de transferencia flexible que puede reproducir por calor el microrelieve sobre la capa exterior de la forma de dosificación, seguido por el enfriamineto y la liberación de la placa de transferencia del recubrimiento.An edible product such as a unit dosage form of a pharmaceutically active substance includes a layer of a material that can receive and retain a high resolution micro-relief that can transmit information. The micro-relief is thermoformable, preferably forming an aqueous solution of hpmc and / or HPC plus a plasticizer and a colorant. Depending on the application, other additives such as surfactants and adhesives can be used. Materials are selected and proportioned to control paleness or color modification of the visual image or effect produced by the relief, to indicate exposure to an unacceptable degree of heat or humidity. The dosage form may consist of the same layer containing the relief bearing the pharmaceutically active substance. In a preferred form, the layer is an outer coating on a core containing a pharmaceutically active substance. The coated tablets are configured to resist the formation of twins. To produce such dosage forms, the coated core is transported in coordination with a mold or a flexible transfer layer that can heat reproduce the micro-relief on the outer layer of the dosage form, followed by cooling and plate release coating transfer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP003605 ECSP003605A (en) | 2000-08-03 | 2000-08-03 | EDIBLE HOLOGRAPHIC PRODUCTS, PARTICULARLY PHARMACEUTICAL, AND METHODS AND APPARATUS FOR PRODUCING THEM |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP003605 ECSP003605A (en) | 2000-08-03 | 2000-08-03 | EDIBLE HOLOGRAPHIC PRODUCTS, PARTICULARLY PHARMACEUTICAL, AND METHODS AND APPARATUS FOR PRODUCING THEM |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP003605A true ECSP003605A (en) | 2000-09-22 |
Family
ID=42041212
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP003605 ECSP003605A (en) | 2000-08-03 | 2000-08-03 | EDIBLE HOLOGRAPHIC PRODUCTS, PARTICULARLY PHARMACEUTICAL, AND METHODS AND APPARATUS FOR PRODUCING THEM |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP003605A (en) |
-
2000
- 2000-08-03 EC ECSP003605 patent/ECSP003605A/en unknown
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