ECSP003710A - INDOLINONES REPLACED IN POSITION 6, ITS PREPARATION AND ITS USE AS MEDICATIONS - Google Patents

INDOLINONES REPLACED IN POSITION 6, ITS PREPARATION AND ITS USE AS MEDICATIONS

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Publication number
ECSP003710A
ECSP003710A ECSP003710A ECSP003710A EC SP003710 A ECSP003710 A EC SP003710A EC SP003710 A ECSP003710 A EC SP003710A EC SP003710 A ECSP003710 A EC SP003710A
Authority
EC
Ecuador
Prior art keywords
preparation
indolinones
medications
replaced
salts
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Frank Hilberg
Armin Heckel
Grunt Ulrike Tontsch
Meel Jacobus Jacques Van
Walter Spevak
Gerhards Jurgen
Norbert Redemann
Walter Rainer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to ECSP003710 priority Critical patent/ECSP003710A/en
Publication of ECSP003710A publication Critical patent/ECSP003710A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

El presente invento se refiere a indolinonas sustituidas en posición 6 de la fórmula general en la que R1 hasta R5 y X están definidos como en la reivindicación 1, sus isómeros y sus sales, especialmente sus sales fisiológicamente compatibles, que presentan valiosas propiedades farmacológicas, especialmente un efecto inhibidor sobre diferentes tirosina-quinasas de receptores y complejos de ciclinas y CDK''s, así como sobre la proliferación de células del endotelio y diferentes células de tumores, a medicamentos que contienen estos compuestos, a su utilización y a procedimientos para su preparación.The present invention relates to indolinones substituted in position 6 of the general formula wherein R1 to R5 and X are defined as in claim 1, their isomers and their salts, especially their physiologically compatible salts, which have valuable pharmacological properties, especially an inhibitory effect on different receptor tyrosine kinases and cyclin and CDK''s complexes, as well as on the proliferation of endothelial cells and different tumor cells, medications containing these compounds, their use and procedures for their preparation .

ECSP003710 2000-10-12 2000-10-12 INDOLINONES REPLACED IN POSITION 6, ITS PREPARATION AND ITS USE AS MEDICATIONS ECSP003710A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ECSP003710 ECSP003710A (en) 2000-10-12 2000-10-12 INDOLINONES REPLACED IN POSITION 6, ITS PREPARATION AND ITS USE AS MEDICATIONS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ECSP003710 ECSP003710A (en) 2000-10-12 2000-10-12 INDOLINONES REPLACED IN POSITION 6, ITS PREPARATION AND ITS USE AS MEDICATIONS

Publications (1)

Publication Number Publication Date
ECSP003710A true ECSP003710A (en) 2001-08-27

Family

ID=42041293

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP003710 ECSP003710A (en) 2000-10-12 2000-10-12 INDOLINONES REPLACED IN POSITION 6, ITS PREPARATION AND ITS USE AS MEDICATIONS

Country Status (1)

Country Link
EC (1) ECSP003710A (en)

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