ECSP034417A - DERIVATIVES OF CYCLOPENTIL-GLUTARAMIDE AS INHIBITORS OF NEUTRAL ENDOPEPTIDASE - Google Patents
DERIVATIVES OF CYCLOPENTIL-GLUTARAMIDE AS INHIBITORS OF NEUTRAL ENDOPEPTIDASEInfo
- Publication number
- ECSP034417A ECSP034417A ECSP034417A ECSP034417A EC SP034417 A ECSP034417 A EC SP034417A EC SP034417 A ECSP034417 A EC SP034417A EC SP034417 A ECSP034417 A EC SP034417A
- Authority
- EC
- Ecuador
- Prior art keywords
- cyclopentil
- glutaramide
- inhibitors
- derivatives
- neutral endopeptidase
- Prior art date
Links
- 102000003729 Neprilysin Human genes 0.000 title 1
- 108090000028 Neprilysin Proteins 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 125000006272 (C3-C7) cycloalkyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
La invención proporciona compuestos de fórmula I en que la R1 es alquilo C1-6 opcionalmente sustituido, cicloalquilo C3-7 opcionalmente sustituido, arilo opcionalmente sustituido o heterocíclico opcionalmente sustituido; n es 0, 1 ó 2; y es - NR 18 S(o)u R 19 o un grupo indicado a continuación:(ver grafico).The invention provides compounds of formula I in which R 1 is optionally substituted C 1-6 alkyl, optionally substituted C 3-7 cycloalkyl, optionally substituted aryl or optionally substituted heterocyclic; n is 0, 1 or 2; and is - NR 18 S (o) or R 19 or a group indicated below: (see graph).
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0016684A GB0016684D0 (en) | 2000-07-06 | 2000-07-06 | Pharmaceutical composition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP034417A true ECSP034417A (en) | 2003-03-10 |
Family
ID=9895192
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP034417 ECSP034417A (en) | 2000-07-06 | 2003-01-06 | DERIVATIVES OF CYCLOPENTIL-GLUTARAMIDE AS INHIBITORS OF NEUTRAL ENDOPEPTIDASE |
Country Status (5)
| Country | Link |
|---|---|
| EC (1) | ECSP034417A (en) |
| GB (1) | GB0016684D0 (en) |
| GT (1) | GT200100131A (en) |
| PY (1) | PY0116111A (en) |
| ZA (2) | ZA200300121B (en) |
-
2000
- 2000-07-06 GB GB0016684A patent/GB0016684D0/en not_active Ceased
-
2001
- 2001-07-04 GT GT200100131A patent/GT200100131A/en unknown
- 2001-07-04 PY PY200100116111A patent/PY0116111A/en unknown
-
2003
- 2003-01-06 ZA ZA200300121A patent/ZA200300121B/en unknown
- 2003-01-06 ZA ZA200300120A patent/ZA200300120B/en unknown
- 2003-01-06 EC ECSP034417 patent/ECSP034417A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PY0116111A (en) | 2003-11-03 |
| ZA200300120B (en) | 2004-01-26 |
| GT200100131A (en) | 2002-03-22 |
| ZA200300121B (en) | 2004-01-21 |
| GB0016684D0 (en) | 2000-08-23 |
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