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Application filed by Glaxosmithkline Biolog SafiledCriticalGlaxosmithkline Biolog Sa
Publication of ECSP034474ApublicationCriticalpatent/ECSP034474A/en
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents
(AREA)
Abstract
Este invento se refiere a un procedimiento para la producción de un antigeno de la hepatitis B adecuado para uso en una vacuna, comprendiendo el procedimiento la purificación del antigeno en presencia de cisteína y a vacunas que comprenden tales antígenos.This invention relates to a process for the production of a hepatitis B antigen suitable for use in a vaccine, the method comprising the purification of the antigen in the presence of cysteine and to vaccines comprising such antigens.