ECSP034567A - SPIROPIRIMIDIN-2,4,6-TRIONA METALOPROTEINASE INHIBITORS - Google Patents

SPIROPIRIMIDIN-2,4,6-TRIONA METALOPROTEINASE INHIBITORS

Info

Publication number
ECSP034567A
ECSP034567A EC2003004567A ECSP034567A ECSP034567A EC SP034567 A ECSP034567 A EC SP034567A EC 2003004567 A EC2003004567 A EC 2003004567A EC SP034567 A ECSP034567 A EC SP034567A EC SP034567 A ECSP034567 A EC SP034567A
Authority
EC
Ecuador
Prior art keywords
spiropirimidin
triona
inhibitors
metaloproteinase inhibitors
metaloproteinase
Prior art date
Application number
EC2003004567A
Other languages
Spanish (es)
Inventor
Mark Carl Noe
Martin James Wythes
Brian S Bronk
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of ECSP034567A publication Critical patent/ECSP034567A/en

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
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Abstract

La presente invención se refiere a inhibidores de 5-espiropirimidin-2,4,6-triona metaloproteinasas de fórmula en la que el citado A es un anillo heterocíclico de 5 a 7 miembros como se define en la memoria descriptiva y a composiciones farmacéuticas y procedimientos de tratamiento de la inflamación, el cáncer y otras dolencias.The present invention relates to 5-spiropyrimidin-2,4,6-trione metalloproteinases inhibitors of the formula wherein said A is a 5- to 7-membered heterocyclic ring as defined in the specification and to pharmaceutical compositions and methods of Treatment of inflammation, cancer and other medical conditions.

EC2003004567A 2000-10-26 2003-04-25 SPIROPIRIMIDIN-2,4,6-TRIONA METALOPROTEINASE INHIBITORS ECSP034567A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24338900P 2000-10-26 2000-10-26

Publications (1)

Publication Number Publication Date
ECSP034567A true ECSP034567A (en) 2003-06-25

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Application Number Title Priority Date Filing Date
EC2003004567A ECSP034567A (en) 2000-10-26 2003-04-25 SPIROPIRIMIDIN-2,4,6-TRIONA METALOPROTEINASE INHIBITORS

Country Status (32)

Country Link
EP (1) EP1332146A2 (en)
JP (1) JP2004518635A (en)
KR (1) KR20040004412A (en)
CN (1) CN1501937A (en)
AP (1) AP2001002318A0 (en)
AR (1) AR035069A1 (en)
AU (1) AU2002210813A1 (en)
BG (1) BG107653A (en)
BR (1) BR0114913A (en)
CA (1) CA2425283A1 (en)
CZ (1) CZ20031083A3 (en)
EA (1) EA005762B1 (en)
EC (1) ECSP034567A (en)
EE (1) EE200300196A (en)
GT (1) GT200100213A (en)
HN (1) HN2001000244A (en)
HR (1) HRP20030332A2 (en)
HU (1) HUP0301577A3 (en)
IL (1) IL154948A0 (en)
IS (1) IS6762A (en)
MA (1) MA26957A1 (en)
MX (1) MXPA03003735A (en)
NO (1) NO20031853L (en)
OA (1) OA12529A (en)
PA (1) PA8531401A1 (en)
PE (1) PE20020589A1 (en)
PL (1) PL366201A1 (en)
SK (1) SK4972003A3 (en)
SV (1) SV2003000705A (en)
TN (1) TNSN01149A1 (en)
WO (1) WO2002034753A2 (en)
ZA (1) ZA200302190B (en)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
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WO2002064571A1 (en) 2001-02-14 2002-08-22 Warner-Lambert Company Llc Pyrimidine matrix metalloproteinase inhibitors
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