ECSP034905A - DRY POWDER INHALATION SYSTEM FOR TRANSPULMONARY ADMINISTRATION - Google Patents

DRY POWDER INHALATION SYSTEM FOR TRANSPULMONARY ADMINISTRATION

Info

Publication number
ECSP034905A
ECSP034905A ECSP034905A ECSP034905A EC SP034905 A ECSP034905 A EC SP034905A EC SP034905 A ECSP034905 A EC SP034905A EC SP034905 A ECSP034905 A EC SP034905A
Authority
EC
Ecuador
Prior art keywords
dry powder
inhalation system
powder inhalation
air
dried composition
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Chikamasa Yamashita
Shigeru Ibaragi
Yuichiro Fukunaga
Akitsuna Akagi
Original Assignee
Otsuka Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharma Co Ltd filed Critical Otsuka Pharma Co Ltd
Publication of ECSP034905A publication Critical patent/ECSP034905A/en

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  • Medicinal Preparation (AREA)

Abstract

La presente invención proporciona un nuevo sistema de inhalación de polvo seco adecuado para la administración transpulmonar. El sistema de inhalación de polvo seco de la invención caracterizado porque usa una combinación de: un recipiente que contiene una composición secada por congelamiento que contiene una única dosis de un ingrediente activo, y tiene:1) una forma tipo pastilla en forma distinta de polvo,2) un índice de desintegración de 0,015 o más, y3) una propiedad para convertir las partículas finas que tienen un diámetro de partícula medio de 10 micrones o menos o una fracción de partículas finas de 10% o más luego de recibir un impacto de aire que tiene una velocidad de aire de al menos 1 m/seg y una velocidad de flujo de aire de al menos 17 ml/seg; yun dispositivo que comprende medios capaces de aplicar dicho impacto de aire a la composición secada por congelamiento en dicho recipiente, y medios para descargar la composición secada por congelamiento en polvo que ha sido dividida en partículas finas.The present invention provides a new dry powder inhalation system suitable for transpulmonary administration. The dry powder inhalation system of the invention characterized in that it uses a combination of: a container containing a freeze-dried composition that contains a single dose of an active ingredient, and has: 1) a tablet-like form in a different powder form , 2) a decay index of 0.015 or more, and 3) a property to convert fine particles having an average particle diameter of 10 microns or less or a fine particle fraction of 10% or more after receiving an impact of air having an air velocity of at least 1 m / sec and an air flow rate of at least 17 ml / sec; and a device comprising means capable of applying said air impact to the freeze dried composition in said container, and means for discharging the powder freeze dried composition that has been divided into fine particles.

ECSP034905 2001-12-28 2003-12-15 DRY POWDER INHALATION SYSTEM FOR TRANSPULMONARY ADMINISTRATION ECSP034905A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2001400871 2001-12-28

Publications (1)

Publication Number Publication Date
ECSP034905A true ECSP034905A (en) 2004-01-28

Family

ID=40418800

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP034905 ECSP034905A (en) 2001-12-28 2003-12-15 DRY POWDER INHALATION SYSTEM FOR TRANSPULMONARY ADMINISTRATION

Country Status (1)

Country Link
EC (1) ECSP034905A (en)

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