ECSP034922A - Pirrolopirimidinas - Google Patents

Pirrolopirimidinas

Info

Publication number
ECSP034922A
ECSP034922A EC2003004922A ECSP034922A ECSP034922A EC SP034922 A ECSP034922 A EC SP034922A EC 2003004922 A EC2003004922 A EC 2003004922A EC SP034922 A ECSP034922 A EC SP034922A EC SP034922 A ECSP034922 A EC SP034922A
Authority
EC
Ecuador
Prior art keywords
compounds
bioisoesters
prodrugs
solvates
oxides
Prior art date
Application number
EC2003004922A
Other languages
English (en)
Inventor
Michael Louis Edwards
David John Aldous
Paul Joseph Cox
Franck Halley
Tahir Nadeem Majid
Shelley Amendola
Stephanie Daniele Deprets
Brian Leslie Pedgrift
Iain Mcfarlane Mclay
Christopher Edlin
Bernard Baudoin
Original Assignee
Aventis Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Inc filed Critical Aventis Pharma Inc
Publication of ECSP034922A publication Critical patent/ECSP034922A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Otolaryngology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

A N-óxidos, profármacos, bioisoésteres ácidos, sales farmacéuticamente aceptables o solvatos de tales compuestos, ó N-óxidos, profármacos, ó bioisoésteres ácidos de tales sales ó solvatos; a composiciones que comprenden tales compuestos; y a métodos de tratamiento que comprenden administrar, a un paciente que lo necesite, tales compuestos y composiciones
EC2003004922A 2001-06-23 2003-12-23 Pirrolopirimidinas ECSP034922A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0115393.1A GB0115393D0 (en) 2001-06-23 2001-06-23 Chemical compounds

Publications (1)

Publication Number Publication Date
ECSP034922A true ECSP034922A (es) 2004-04-28

Family

ID=9917225

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2003004922A ECSP034922A (es) 2001-06-23 2003-12-23 Pirrolopirimidinas

Country Status (22)

Country Link
EP (1) EP1404676A1 (es)
JP (1) JP4344607B2 (es)
CN (1) CN1294135C (es)
AU (1) AU2002314325B8 (es)
BR (1) BR0210652A (es)
CA (1) CA2451932C (es)
CZ (1) CZ20033443A3 (es)
EA (1) EA007415B1 (es)
EC (1) ECSP034922A (es)
EE (1) EE05432B1 (es)
GB (1) GB0115393D0 (es)
HU (1) HUP0400300A3 (es)
ME (1) MEP19308A (es)
NZ (1) NZ529766A (es)
OA (1) OA12632A (es)
PL (1) PL374096A1 (es)
RS (1) RS51698B (es)
SK (1) SK15882003A3 (es)
TN (1) TNSN03144A1 (es)
TR (1) TR200302242T2 (es)
UA (1) UA76760C2 (es)
WO (1) WO2003000695A1 (es)

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WO2006023931A2 (en) 2004-08-18 2006-03-02 Takeda San Diego, Inc. Kinase inhibitors
FR2876103B1 (fr) * 2004-10-01 2008-02-22 Aventis Pharma Sa Nouveaux derives bis-azaindoles, leur preparation et leur utilisation pharmaceutique comme inhibiteurs de kinases
EP1812439B2 (en) 2004-10-15 2017-12-06 Takeda Pharmaceutical Company Limited Kinase inhibitors
FR2878849B1 (fr) 2004-12-06 2008-09-12 Aventis Pharma Sa Indoles substitues, compositions les contenant, procede de fabrication et utilisation
EP1896134A2 (en) 2005-06-13 2008-03-12 Rigel Pharmaceuticals, Inc. Methods and compositions for treating degenerative bone disorders
US8119655B2 (en) 2005-10-07 2012-02-21 Takeda Pharmaceutical Company Limited Kinase inhibitors
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US8691807B2 (en) 2011-06-20 2014-04-08 Incyte Corporation Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as JAK inhibitors
TW201313721A (zh) 2011-08-18 2013-04-01 Incyte Corp 作為ｊａｋ抑制劑之環己基氮雜環丁烷衍生物
UA111854C2 (uk) 2011-09-07 2016-06-24 Інсайт Холдінгс Корпорейшн Способи і проміжні сполуки для отримання інгібіторів jak
CN104662018B (zh) 2012-04-20 2017-10-24 阿迪维纳斯治疗有限公司 取代的杂双环化合物、组合物及其医疗应用
TW201406761A (zh) 2012-05-18 2014-02-16 Incyte Corp 做爲ｊａｋ抑制劑之哌啶基環丁基取代之吡咯并吡啶及吡咯并嘧啶衍生物
RU2611010C2 (ru) 2012-07-26 2017-02-17 Глаксо Груп Лимитед 2-(Азаиндол-2-ил)бензимидазолы в качестве ингибиторов PAD4
JP6318156B2 (ja) * 2012-09-06 2018-04-25 プレキシコン インコーポレーテッドＰｌｅｘｘｉｋｏｎ Ｉｎｃ． キナーゼをモジュレートするための化合物および方法、ならびにその指標
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Also Published As

Publication number Publication date
HUP0400300A3 (en) 2010-12-28
OA12632A (en) 2006-06-14
NZ529766A (en) 2008-11-28
UA76760C2 (uk) 2006-09-15
AU2002314325B2 (en) 2009-01-08
JP2005508300A (ja) 2005-03-31
TNSN03144A1 (en) 2005-12-23
EP1404676A1 (en) 2004-04-07
PL374096A1 (en) 2005-09-19
EE200400003A (et) 2004-02-16
TR200302242T2 (tr) 2004-12-21
CA2451932A1 (en) 2003-01-03
SK15882003A3 (sk) 2004-07-07
EA007415B1 (ru) 2006-10-27
JP4344607B2 (ja) 2009-10-14
AU2002314325B8 (en) 2009-01-29
CZ20033443A3 (en) 2004-03-17
MEP19308A (en) 2010-06-10
GB0115393D0 (en) 2001-08-15
CN1518552A (zh) 2004-08-04
RS99203A (sr) 2006-12-15
EE05432B1 (et) 2011-06-15
HUP0400300A2 (en) 2007-08-28
EA200400073A1 (ru) 2004-08-26
CA2451932C (en) 2009-12-29
BR0210652A (pt) 2004-08-10
WO2003000695A8 (en) 2004-03-11
CN1294135C (zh) 2007-01-10
WO2003000695A1 (en) 2003-01-03
RS51698B (sr) 2011-10-31

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