ECSP045074A - HYDROXYPIRIMIDINONE CARBOXAMIDE N-REPLACED HIV INTEGRAS INHIBITORS - Google Patents
HYDROXYPIRIMIDINONE CARBOXAMIDE N-REPLACED HIV INTEGRAS INHIBITORSInfo
- Publication number
- ECSP045074A ECSP045074A ECSP045074A ECSP045074A EC SP045074 A ECSP045074 A EC SP045074A EC SP045074 A ECSP045074 A EC SP045074A EC SP045074 A ECSP045074 A EC SP045074A
- Authority
- EC
- Ecuador
- Prior art keywords
- hiv
- hydroxypirimidinone
- carboxamide
- inhibitors
- replaced
- Prior art date
Links
- 150000003857 carboxamides Chemical class 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 208000030507 AIDS Diseases 0.000 abstract 2
- 208000031886 HIV Infections Diseases 0.000 abstract 2
- 208000037357 HIV infectious disease Diseases 0.000 abstract 2
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 abstract 2
- -1 hydroxypyrimidinone carboxamides Chemical class 0.000 abstract 2
- 108010002459 HIV Integrase Proteins 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000002924 anti-infective effect Effects 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 229960005475 antiinfective agent Drugs 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 229940121357 antivirals Drugs 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 239000002955 immunomodulating agent Substances 0.000 abstract 1
- 229940121354 immunomodulator Drugs 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención está dirigida a hidroxipirimidinona carboxamidas novedosas. Estos compuestos son útiles en la inhibición de la integrasa de VIH, la prevención de la infección por VIH, el tratamiento de la infección por VIH y en la prevención, tratamiento y retraso de la aparición de SIDA y/o ARC, ya sea como compuestos o sus sales farmacéuticamente aceptables o hidratos (cuando sea apropiado), o como ingredientes de la composición farmacéutica, y sea o no en combinación con otros antivirales de VIH/SIDA, anti-infecciosos, inmunomoduladores, antibióticos o vacunas. Más particularmente, la presente invención incluye un compuesto de la Fórmula (I) cuya descripción de elementos se encuentra en la primera reivindicación.The present invention is directed to novel hydroxypyrimidinone carboxamides. These compounds are useful in inhibiting HIV integrase, preventing HIV infection, treating HIV infection and preventing, treating and delaying the onset of AIDS and / or ARC, either as compounds. or its pharmaceutically acceptable salts or hydrates (when appropriate), or as ingredients of the pharmaceutical composition, whether or not in combination with other HIV / AIDS antivirals, anti-infectives, immunomodulators, antibiotics or vaccines. More particularly, the present invention includes a compound of Formula (I) whose description of elements is found in the first claim.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP045074 ECSP045074A (en) | 2004-04-22 | 2004-04-22 | HYDROXYPIRIMIDINONE CARBOXAMIDE N-REPLACED HIV INTEGRAS INHIBITORS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP045074 ECSP045074A (en) | 2004-04-22 | 2004-04-22 | HYDROXYPIRIMIDINONE CARBOXAMIDE N-REPLACED HIV INTEGRAS INHIBITORS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP045074A true ECSP045074A (en) | 2004-05-28 |
Family
ID=40435097
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP045074 ECSP045074A (en) | 2004-04-22 | 2004-04-22 | HYDROXYPIRIMIDINONE CARBOXAMIDE N-REPLACED HIV INTEGRAS INHIBITORS |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP045074A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9296769B2 (en) | 2011-08-16 | 2016-03-29 | Gilead Sciences, Inc. | Tenofovir alafenamide hemifumarate |
-
2004
- 2004-04-22 EC ECSP045074 patent/ECSP045074A/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9296769B2 (en) | 2011-08-16 | 2016-03-29 | Gilead Sciences, Inc. | Tenofovir alafenamide hemifumarate |
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