ECSP055578A - Piston de volumen eficiente, con minima facilidad de ceder, para sistemas osmoticos de entrega de droga - Google Patents

Piston de volumen eficiente, con minima facilidad de ceder, para sistemas osmoticos de entrega de droga

Info

Publication number
ECSP055578A
ECSP055578A EC2005005578A ECSP055578A ECSP055578A EC SP055578 A ECSP055578 A EC SP055578A EC 2005005578 A EC2005005578 A EC 2005005578A EC SP055578 A ECSP055578 A EC SP055578A EC SP055578 A ECSP055578 A EC SP055578A
Authority
EC
Ecuador
Prior art keywords
capsule
piston
agent
osmotic
giving
Prior art date
Application number
EC2005005578A
Other languages
English (en)
Inventor
Scott D Lautenbach
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Publication of ECSP055578A publication Critical patent/ECSP055578A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M2005/14513—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons with secondary fluid driving or regulating the infusion

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención se refiere a sistemas osmóticos para entrega de agentes benéficos. Más particularmente, la presente invención se refiere a una bomba osmótica que tiene un pistón de volumen eficiente, con mínima facilidad de ceder.
EC2005005578A 2002-06-26 2005-01-26 Piston de volumen eficiente, con minima facilidad de ceder, para sistemas osmoticos de entrega de droga ECSP055578A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39200402P 2002-06-26 2002-06-26

Publications (1)

Publication Number Publication Date
ECSP055578A true ECSP055578A (es) 2005-04-18

Family

ID=30000792

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2005005578A ECSP055578A (es) 2002-06-26 2005-01-26 Piston de volumen eficiente, con minima facilidad de ceder, para sistemas osmoticos de entrega de droga

Country Status (19)

Country Link
US (3) US6939556B2 (es)
EP (1) EP1551493B1 (es)
JP (1) JP4485945B2 (es)
KR (1) KR101046903B1 (es)
CN (1) CN100453130C (es)
AT (1) ATE376854T1 (es)
AU (1) AU2003256308B2 (es)
BR (1) BR0312429A (es)
CA (1) CA2490544C (es)
DE (1) DE60317225T2 (es)
EC (1) ECSP055578A (es)
ES (1) ES2295642T3 (es)
IL (1) IL165975A (es)
MX (1) MXPA05000224A (es)
NO (1) NO20050368L (es)
NZ (1) NZ537628A (es)
TW (1) TW200531709A (es)
WO (1) WO2004002565A1 (es)
ZA (1) ZA200500744B (es)

Families Citing this family (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY125870A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system flow modulator apparatus and method
US7258869B1 (en) 1999-02-08 2007-08-21 Alza Corporation Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicle
US7919109B2 (en) 1999-02-08 2011-04-05 Intarcia Therapeutics, Inc. Stable non-aqueous single phase viscous vehicles and formulations utilizing such vehicles
EP1578398A2 (en) * 2002-12-19 2005-09-28 ALZA Corporation Stable, non-aqueous, single-phase gels and formulations thereof for delivery from an implantable device
US7731947B2 (en) * 2003-11-17 2010-06-08 Intarcia Therapeutics, Inc. Composition and dosage form comprising an interferon particle formulation and suspending vehicle
EP1610761A2 (en) * 2003-03-31 2006-01-04 Alza Corporation Osmotic delivery system and method for decreasing start-up times for osmotic delivery systems
CA2520610A1 (en) * 2003-03-31 2004-10-21 Alza Corporation Osmotic pump with means for dissipating internal pressure
WO2005046639A2 (en) * 2003-11-06 2005-05-26 Alza Corporation Modular imbibition rate reducer for use with implantable osmotic pump
US20050266087A1 (en) * 2004-05-25 2005-12-01 Gunjan Junnarkar Formulations having increased stability during transition from hydrophobic vehicle to hydrophilic medium
CA2588295C (en) 2004-11-23 2013-10-22 Adamas Pharma, Llc Method and composition for administering an nmda receptor antagonist to a subject
US7619007B2 (en) 2004-11-23 2009-11-17 Adamas Pharmaceuticals, Inc. Method and composition for administering an NMDA receptor antagonist to a subject
CA2588296A1 (en) 2004-11-24 2006-06-01 Neuromolecular Pharmaceuticals, Inc. Composition comprising an nmda receptor antagonist and levodopa and use thereof for treating neurological disease
JP2008528698A (ja) * 2005-02-03 2008-07-31 インターシア セラピューティクス，インコーポレイティド 埋め込み可能なインターフェロン含有デバイス
US11246913B2 (en) 2005-02-03 2022-02-15 Intarcia Therapeutics, Inc. Suspension formulation comprising an insulinotropic peptide
WO2006083761A2 (en) 2005-02-03 2006-08-10 Alza Corporation Solvent/polymer solutions as suspension vehicles
US7959938B2 (en) 2005-03-15 2011-06-14 Intarcia Therapeutics, Inc. Polyoxaester suspending vehicles for use with implantable delivery systems
JP5666087B2 (ja) 2005-04-06 2015-02-12 アダマス・ファーマシューティカルズ・インコーポレーテッド Ｃｎｓ関連疾患の治療のための方法及び組成物
EP1948183B1 (en) * 2005-10-13 2013-12-18 Duke University Compositions for the treatment and prevention of heart disease and methods of using same
KR101106510B1 (ko) 2006-05-30 2012-01-20 인타르시아 세라퓨틱스 인코포레이티드 투피스, 내부채널 삼투압 전달 시스템 유동 조절기
CA2670821C (en) * 2006-08-09 2012-05-15 Intarcia Therapeutics, Inc. Osmotic delivery systems and piston assemblies
CA2683610C (en) * 2007-04-23 2013-01-08 Intarcia Therapeutics, Inc. Suspension formulations of insulinotropic peptides and uses thereof
US8105261B2 (en) * 2007-07-02 2012-01-31 Cardiac Pacemakers, Inc. Osmotic devices and methods for diuretic therapy
US8394644B2 (en) * 2007-11-08 2013-03-12 Honeywell International Inc. Microfluidic osmotic pump
WO2009102467A2 (en) 2008-02-13 2009-08-20 Intarcia Therapeutics, Inc. Devices, formulations, and methods for delivery of multiple beneficial agents
KR101419583B1 (ko) * 2008-10-15 2014-07-25 인타르시아 세라퓨틱스 인코포레이티드 고농축 약물 입자, 제형, 현탁액 및 이들의 용도
CA2765630C (en) * 2009-06-26 2016-07-05 Taris Biomedical, Inc. Solid drug tablets for implantable drug delivery devices
MX378797B (es) 2009-09-28 2025-03-10 Intarcia Therapeutics Inc Establecimiento y/o terminacion rapidos de suministro de estado estable sustancial de farmaco.
EP2482677A1 (en) 2009-09-30 2012-08-08 The Regents of The University of California Cofactors and methods for use for individuals
AU2010325960C1 (en) 2009-12-02 2015-08-06 Adamas Pharma, Llc Amantadine compositions and methods of use
US20120208755A1 (en) 2011-02-16 2012-08-16 Intarcia Therapeutics, Inc. Compositions, Devices and Methods of Use Thereof for the Treatment of Cancers
EP3466418A1 (en) 2011-07-15 2019-04-10 NuSirt Sciences, Inc. Compositions and methods for modulating metabolic pathways
US9198454B2 (en) 2012-03-08 2015-12-01 Nusirt Sciences, Inc. Compositions, methods, and kits for regulating energy metabolism
MX2015004636A (es) * 2012-10-12 2015-10-22 Lilly Co Eli Motores químicos y métodos para su uso, especialmente en la inyección de fluidos altamente viscosos.
SG11201503774PA (en) 2012-11-13 2015-06-29 Nusirt Sciences Inc Compositions and methods for increasing energy metabolism
AU2014207707B2 (en) 2013-01-15 2018-11-01 Nusirt Sciences, Inc. Treating pulmonary conditions
JP2016508842A (ja) * 2013-03-05 2016-03-24 タリス バイオメディカル エルエルシー 装置の開口部を通じて制御された薬物放出のための薬物送達装置及び方法
CN105228627B (zh) 2013-03-15 2018-07-13 纽斯尔特科学公司 亮氨酸和烟酸降低脂质水平
US10154971B2 (en) 2013-06-17 2018-12-18 Adamas Pharma, Llc Methods of administering amantadine
MX2016011063A (es) 2014-02-27 2016-11-30 Nusirt Sciences Inc Composiciones y metodos para la reduccion o prevencion de esteatosis hepatica.
US9889085B1 (en) 2014-09-30 2018-02-13 Intarcia Therapeutics, Inc. Therapeutic methods for the treatment of diabetes and related conditions for patients with high baseline HbA1c
CN113598842A (zh) 2015-06-03 2021-11-05 因塔西亚制药公司 植入物放置和移除系统
CA3003747A1 (en) 2015-11-05 2017-05-11 The General Hospital Corporation Intrathecal delivery of nucleic acid sequences encoding abcd1 for treatment of adrenomyeloneuropathy
EP3397253A1 (en) 2015-12-30 2018-11-07 Adamas Pharmaceuticals, Inc. Methods and compositions for the treatment of seizure-related disorders
KR102574993B1 (ko) 2016-05-16 2023-09-06 인타르시아 세라퓨틱스 인코포레이티드 글루카곤-수용체 선택적 폴리펩티드 및 이들의 이용 방법
USD840030S1 (en) 2016-06-02 2019-02-05 Intarcia Therapeutics, Inc. Implant placement guide
USD860451S1 (en) 2016-06-02 2019-09-17 Intarcia Therapeutics, Inc. Implant removal tool
US10406336B2 (en) 2016-08-03 2019-09-10 Neil S. Davey Adjustable rate drug delivery implantable device
KR20190086460A (ko) 2016-10-20 2019-07-22 더 유나이티드 스테이츠 오브 어메리카, 애즈 리프리젠티드 바이 더 세크러테리, 디파트먼트 오브 헬쓰 앤드 휴먼 서비씨즈 신경보호 폴리펩티드를 중추 신경계에 전달하는 방법
WO2018129058A1 (en) 2017-01-03 2018-07-12 Intarcia Therapeutics, Inc. Methods comprising continuous administration of a glp-1 receptor agonist and co-adminstration of a drug
JP6841937B2 (ja) 2017-02-17 2021-03-10 イーライ リリー アンド カンパニー 化学反応による流体の送達のためのプロセスおよびデバイス
JP2020510028A (ja) 2017-03-08 2020-04-02 インターシア セラピューティクス，インコーポレイティド 薬物送達デバイスから吐き気誘発性化合物の投与のための装置及び方法
WO2018200885A1 (en) 2017-04-26 2018-11-01 Neurocentria, Inc. Magnesium compositions and methods of use
CN111050826B (zh) 2017-09-08 2022-05-31 伊莱利利公司 用于控制药物递送装置内的气体生成的系统
USD933219S1 (en) 2018-07-13 2021-10-12 Intarcia Therapeutics, Inc. Implant removal tool and assembly
WO2020041774A1 (en) 2018-08-23 2020-02-27 Baywind Bioventures Capsule device for delivery of active agent to gastrointestinal tract
KR102911883B1 (ko) 2018-10-11 2026-01-13 인타르시아 세라퓨틱스 인코포레이티드 인간 아밀린 유사체 폴리펩타이드 및 사용 방법
CN113226404B (zh) 2018-12-19 2024-08-23 伊莱利利公司 用于输送治疗流体的设备
EP3897779B1 (en) 2018-12-19 2024-08-07 Eli Lilly and Company Devices and processes for delivery of therapeutic fluids
WO2022202881A1 (ja) * 2021-03-25 2022-09-29 テルモ株式会社 持続投与装置
WO2025160155A1 (en) 2024-01-22 2025-07-31 The Broad Institute, Inc. Epigenetic targeting of prion diseases

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4753651A (en) 1982-08-30 1988-06-28 Alza Corporation Self-driven pump
US4765989A (en) * 1983-05-11 1988-08-23 Alza Corporation Osmotic device for administering certain drugs
US4558888A (en) * 1983-09-19 1985-12-17 Minnesota Mining And Manufacturing Company Strip of binding tape
US4874388A (en) 1987-06-25 1989-10-17 Alza Corporation Multi-layer delivery system
US5034229A (en) * 1988-12-13 1991-07-23 Alza Corporation Dispenser for increasing feed conversion of hog
US5728088A (en) * 1988-12-13 1998-03-17 Alza Corporation Osmotic system for delivery of fluid-sensitive somatotropins to bovine animals
US4969884A (en) * 1988-12-28 1990-11-13 Alza Corporation Osmotically driven syringe
US5234424A (en) * 1988-12-28 1993-08-10 Alza Corporation Osmotically driven syringe
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
US5030216A (en) * 1989-12-15 1991-07-09 Alza Corporation Osmotically driven syringe
US5324280A (en) * 1990-04-02 1994-06-28 Alza Corporation Osmotic dosage system for delivering a formulation comprising liquid carrier and drug
US5180591A (en) 1990-07-11 1993-01-19 Alza Corporation Delivery device with a protective sleeve
US5234692A (en) * 1990-07-11 1993-08-10 Alza Corporation Delivery device with a protective sleeve
US5443459A (en) * 1991-01-30 1995-08-22 Alza Corporation Osmotic device for delayed delivery of agent
US5861166A (en) * 1991-03-12 1999-01-19 Alza Corporation Delivery device providing beneficial agent stability
CN2085662U (zh) * 1991-03-29 1991-10-02 毕勇 药物″渗透泵″的生产装置
US5137727A (en) 1991-06-12 1992-08-11 Alza Corporation Delivery device providing beneficial agent stability
ATE183642T1 (de) 1991-10-04 1999-09-15 Yoshitomi Pharmaceutical Tablette mit verzögerter freisetzung
WO1993006819A1 (en) * 1991-10-10 1993-04-15 Alza Corporation Osmotic drug delivery devices with hydrophobic wall materials
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5456679A (en) * 1992-02-18 1995-10-10 Alza Corporation Delivery devices with pulsatile effect
US5209746A (en) 1992-02-18 1993-05-11 Alza Corporation Osmotically driven delivery devices with pulsatile effect
US5308348A (en) * 1992-02-18 1994-05-03 Alza Corporation Delivery devices with pulsatile effect
US5221278A (en) * 1992-03-12 1993-06-22 Alza Corporation Osmotically driven delivery device with expandable orifice for pulsatile delivery effect
US5260069A (en) * 1992-11-27 1993-11-09 Anda Sr Pharmaceuticals Inc. Pulsatile particles drug delivery system
US5540665A (en) * 1994-01-31 1996-07-30 Alza Corporation Gas driven dispensing device and gas generating engine therefor
US5458888A (en) * 1994-03-02 1995-10-17 Andrx Pharmaceuticals, Inc. Controlled release tablet formulation
US5690952A (en) * 1995-06-07 1997-11-25 Judy A. Magruder et al. Implantable system for delivery of fluid-sensitive agents to animals
US6261584B1 (en) * 1996-02-02 2001-07-17 Alza Corporation Sustained delivery of an active agent using an implantable system
US6132420A (en) * 1996-02-02 2000-10-17 Alza Corporation Osmotic delivery system and method for enhancing start-up and performance of osmotic delivery systems
US6156331A (en) * 1996-02-02 2000-12-05 Alza Corporation Sustained delivery of an active agent using an implantable system
US6395292B2 (en) * 1996-02-02 2002-05-28 Alza Corporation Sustained delivery of an active agent using an implantable system
ATE277595T1 (de) * 1996-02-02 2004-10-15 Alza Corp Implantierbares system mit verzögerter wirkstofffreisetzung
ZA981610B (en) * 1997-03-24 1999-08-26 Alza Corp Self adjustable exit port.
MY125870A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system flow modulator apparatus and method
MY125849A (en) * 1997-07-25 2006-08-30 Alza Corp Osmotic delivery system, osmotic delivery system semipermeable body assembly, and method for controlling delivery rate of beneficial agents from osmotic delivery systems
WO1999033446A1 (en) 1997-12-29 1999-07-08 Alza Corporation Osmotic delivery system with membrane plug retention mechanism
AU765909C (en) * 1998-12-17 2004-09-23 Alza Corporation Conversion of liquid filled gelatin capsules into controlled release systems by multiple coatings
US20020197235A1 (en) * 2000-11-03 2002-12-26 Moran Stanford Mark Method for short-term and long-term drug dosimetry

Also Published As

Publication number Publication date
KR101046903B1 (ko) 2011-07-06
US20070088337A1 (en) 2007-04-19
WO2004002565A1 (en) 2004-01-08
BR0312429A (pt) 2005-04-19
US20040019345A1 (en) 2004-01-29
ATE376854T1 (de) 2007-11-15
TW200531709A (en) 2005-10-01
US7112335B2 (en) 2006-09-26
EP1551493B1 (en) 2007-10-31
NO20050368L (no) 2005-01-24
CA2490544C (en) 2011-04-19
CN100453130C (zh) 2009-01-21
AU2003256308A1 (en) 2004-01-19
EP1551493A1 (en) 2005-07-13
CA2490544A1 (en) 2004-01-08
AU2003256308B2 (en) 2008-07-03
KR20050026416A (ko) 2005-03-15
DE60317225D1 (de) 2007-12-13
ZA200500744B (en) 2006-03-29
JP4485945B2 (ja) 2010-06-23
NZ537628A (en) 2005-12-23
US6939556B2 (en) 2005-09-06
US20060111693A1 (en) 2006-05-25
JP2005530588A (ja) 2005-10-13
HK1080402A1 (en) 2006-04-28
ES2295642T3 (es) 2008-04-16
DE60317225T2 (de) 2008-05-29
MXPA05000224A (es) 2005-06-03
IL165975A (en) 2009-07-20
IL165975A0 (en) 2006-01-15
CN1671439A (zh) 2005-09-21

Similar Documents

Publication Publication Date Title
ZA200500744B (en) Minimally compliant, volume efficient piston for osmotic drug delivery systems
WO2000040218A3 (en) Osmotic delivery system having space efficient piston
BRPI0407366A (pt) Envoltório com liberação de pressão por ação de came
CO5700800A2 (es) Dispositivo de administracion controlada de farmaco para paciente
AU1808797A (en) Cartridge-based drug delivery device
ES2055649B1 (es) Bombas osmoticas.
WO2002045771A3 (en) Microneedle adapter
CA2402637A1 (en) Valve for osmotic devices
MX9704653A (es) Suministro de particulas.
WO2008100321A3 (en) Syringe-in-syringe hollow plunger with integral seal and rupturable membrane and related methods
WO2001026813A3 (en) Microfluidics without electrically of mechanically operated pumps
EP2446911A3 (en) Self-contained portable apparatus for administration of a drug solution
JP2005530588A5 (es)
US20020035351A1 (en) Single barrel double chamber syringe
ES2671180T3 (es) Émbolo para cuerpo hueco medicinal y cuerpo hueco medicinal
WO1998057695A8 (en) Drug delivery system
BR9708126A (pt) Bomba de platina
MX2008001043A (es) Contenedor.
WO2020002263A8 (en) Needleless injection system
WO2004041068A3 (en) Guided capsule for wireless endoscopy, biopsy, and drug delivery
PE20090543A1 (es) Dispositivo calentador
US20050215850A1 (en) Syringe pump
AR036914A1 (es) Valvula para fluidos criogenicos, y aplicacion para el empleo de dicha valvula
AU2003250952A1 (en) Use of a disposable container, microfluidic device and method for processing molecules
ITMO20040184A1 (it) 'applicatore per sostanze fluide per uso medico e o cosmetico'.