ECSP055713A - NEW ANTIMICOBACTERIAL COMPOUNDS - Google Patents

NEW ANTIMICOBACTERIAL COMPOUNDS

Info

Publication number
ECSP055713A
ECSP055713A ECSP055713A ECSP055713A EC SP055713 A ECSP055713 A EC SP055713A EC SP055713 A ECSP055713 A EC SP055713A EC SP055713 A ECSP055713 A EC SP055713A
Authority
EC
Ecuador
Prior art keywords
compounds
new
formula
antimicobacterial
mdr
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Sudershan Kumar Arora
Neelima Sinha
Sanjay Jain
Ram Shankar Upadhayaya
Gourhari Jana
Shankar Ajay
Rakesh Kumar Sinha
Original Assignee
Lupin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lupin Ltd filed Critical Lupin Ltd
Priority to ECSP055713 priority Critical patent/ECSP055713A/en
Publication of ECSP055713A publication Critical patent/ECSP055713A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

RESUMEN DE LA INVENCIÓN Nuevos derivados de pirrol de la fórmula (I) y sus sales por adición de ácido farmacéuticamente aceptables que tienen actividad antimicobacteriana superior contra cepas clínicamente sensibles así como resistentes de Mycobacterium tuberculosis que también tienen menor toxicidad en comparación a compuestos conocidos. El uso de los nuevos compuestos de la fórmula (I) para tratamiento de tuberculosis latente incluyendo Tuberculosis Resistente a Múltiples Fármacos (MDR TB). Los métodos para la preparación de los nuevos compuestos, composiciones farmacéuticas que contienen los nuevos compuestos y método de tratamiento de MDR TB mediante administración de compuestos de la fórmula (I).SUMMARY OF THE INVENTION New pyrrole derivatives of the formula (I) and their pharmaceutically acceptable acid addition salts having superior antimicobacterial activity against clinically sensitive as well as resistant Mycobacterium tuberculosis strains that also have lower toxicity compared to known compounds. The use of the new compounds of the formula (I) for the treatment of latent tuberculosis including Multiple Drug Resistant Tuberculosis (MDR TB). The methods for the preparation of the new compounds, pharmaceutical compositions containing the new compounds and method of treatment of MDR TB by administration of compounds of the formula (I).

ECSP055713 2005-03-31 2005-03-31 NEW ANTIMICOBACTERIAL COMPOUNDS ECSP055713A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ECSP055713 ECSP055713A (en) 2005-03-31 2005-03-31 NEW ANTIMICOBACTERIAL COMPOUNDS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ECSP055713 ECSP055713A (en) 2005-03-31 2005-03-31 NEW ANTIMICOBACTERIAL COMPOUNDS

Publications (1)

Publication Number Publication Date
ECSP055713A true ECSP055713A (en) 2005-11-22

Family

ID=40202991

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP055713 ECSP055713A (en) 2005-03-31 2005-03-31 NEW ANTIMICOBACTERIAL COMPOUNDS

Country Status (1)

Country Link
EC (1) ECSP055713A (en)

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