ECSP055976A - 1- (4- (2-PIPERIDINYLETOXI) PHENOXI) CHLORHYDRATE -2- (4-METHANOSULPHONYL PHENYL) -6-CRISTALINE HYDROXYLPHALENE NOT SOLVATED - Google Patents

1- (4- (2-PIPERIDINYLETOXI) PHENOXI) CHLORHYDRATE -2- (4-METHANOSULPHONYL PHENYL) -6-CRISTALINE HYDROXYLPHALENE NOT SOLVATED

Info

Publication number
ECSP055976A
ECSP055976A EC2005005976A ECSP055976A ECSP055976A EC SP055976 A ECSP055976 A EC SP055976A EC 2005005976 A EC2005005976 A EC 2005005976A EC SP055976 A ECSP055976 A EC SP055976A EC SP055976 A ECSP055976 A EC SP055976A
Authority
EC
Ecuador
Prior art keywords
solvated
piperidinyletoxi
methanosulphonyl
hydroxylphalene
cristaline
Prior art date
Application number
EC2005005976A
Other languages
Spanish (es)
Inventor
David Michael Remick
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ECSP055976A publication Critical patent/ECSP055976A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención se refiere a clorhidrato de 1-(4-(2-piperidiniletoxi)fenoxi)-2-(4-metanosulfonilfenil)-6-hidroxinaftaleno cristalino no solvatado.The present invention relates to non-solvated crystalline 1- (4- (2-piperidinylethoxy) phenoxy) -2- (4-methanesulfonylphenyl) -6-hydroxynaphthalene hydrochloride hydrochloride.

EC2005005976A 2003-02-25 2005-08-23 1- (4- (2-PIPERIDINYLETOXI) PHENOXI) CHLORHYDRATE -2- (4-METHANOSULPHONYL PHENYL) -6-CRISTALINE HYDROXYLPHALENE NOT SOLVATED ECSP055976A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US45023303P 2003-02-25 2003-02-25

Publications (1)

Publication Number Publication Date
ECSP055976A true ECSP055976A (en) 2006-01-16

Family

ID=36680233

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2005005976A ECSP055976A (en) 2003-02-25 2005-08-23 1- (4- (2-PIPERIDINYLETOXI) PHENOXI) CHLORHYDRATE -2- (4-METHANOSULPHONYL PHENYL) -6-CRISTALINE HYDROXYLPHALENE NOT SOLVATED

Country Status (9)

Country Link
JP (1) JP2007537991A (en)
KR (1) KR100693242B1 (en)
CN (1) CN100348192C (en)
CO (1) CO5590928A2 (en)
EA (1) EA007978B1 (en)
EC (1) ECSP055976A (en)
NZ (1) NZ541126A (en)
PL (1) PL377494A1 (en)
ZA (1) ZA200506547B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116438177B (en) * 2021-01-28 2025-09-16 江苏亚虹医药科技股份有限公司 Targeted chimeric compounds, pharmaceutical compositions containing same, and preparation methods and uses thereof
JP2024518832A (en) * 2021-05-14 2024-05-07 江▲蘇▼▲亞▼虹医▲薬▼科技股▲フン▼有限公司 Naphthalene ring-containing compound, pharmaceutical composition containing same and use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7501441B1 (en) * 1994-09-20 2009-03-10 Eli Lilly And Company Naphthyl compounds, intermediates, processes, compositions, and methods
US5998401A (en) * 1995-02-28 1999-12-07 Eli Lilly And Company Naphthyl compounds, intermediates, compositions, and methods
PT791591E (en) * 1996-02-22 2001-12-28 Lilly Co Eli BENZOTIOPHENES, FORMULATIONS CONTAINING THEM AND METHODS
CA2217810A1 (en) * 1996-10-10 1998-04-10 Eli Lilly And Company 2-aryl-3-aminoaryloxynaphthyl compounds, intermediates, compositions and methods
PL374845A1 (en) * 2002-07-22 2005-11-14 Eli Lilly And Company Selective estrogen receptor modulators containing a phenylsulfonyl group

Also Published As

Publication number Publication date
CN100348192C (en) 2007-11-14
KR20050106039A (en) 2005-11-08
PL377494A1 (en) 2006-02-06
CN1753676A (en) 2006-03-29
KR100693242B1 (en) 2007-03-12
CO5590928A2 (en) 2005-12-30
JP2007537991A (en) 2007-12-27
ZA200506547B (en) 2006-11-29
NZ541126A (en) 2008-07-31
EA200501339A1 (en) 2006-02-24
EA007978B1 (en) 2007-02-27

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