ECSP056190A - Compuestos utiles en la terapia de la enfermedad de alzheimer y formulaciones que los contienen - Google Patents

Compuestos utiles en la terapia de la enfermedad de alzheimer y formulaciones que los contienen

Info

Publication number
ECSP056190A
ECSP056190A EC2005006190A ECSP056190A ECSP056190A EC SP056190 A ECSP056190 A EC SP056190A EC 2005006190 A EC2005006190 A EC 2005006190A EC SP056190 A ECSP056190 A EC SP056190A EC SP056190 A ECSP056190 A EC SP056190A
Authority
EC
Ecuador
Prior art keywords
alzheimer
formulations containing
useful compounds
salts
disease therapy
Prior art date
Application number
EC2005006190A
Other languages
English (en)
Inventor
Ezio Bombardelli
Gabriela Fontana
Luisella Verotta
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of ECSP056190A publication Critical patent/ECSP056190A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/743—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups having unsaturation outside the rings, e.g. humulones, lupulones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
    • C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
    • C07C49/723—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic
    • C07C49/727—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system
    • C07C49/733—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system having two rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Las sales de floroglucinol, en particular sales de tetrahidro y octahidrohiperforina o derivados de adhiperforina y de colupon con alcaloides inhibidores de acetilcolinesterasa y métodos para la preparación de los mismos; dichas sales que son útiles para el tratamiento de depresión y enfermedad de Alzheimer pueden administrarse como formulaciones farmacéuticas convencionales o como preparaciones transdérmicas de liberación controlada.
EC2005006190A 2003-05-30 2005-11-28 Compuestos utiles en la terapia de la enfermedad de alzheimer y formulaciones que los contienen ECSP056190A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT001098A ITMI20031098A1 (it) 2003-05-30 2003-05-30 Composti utili nella terapia del morbo di alzheimer e formulazioni che li contengono
PCT/EP2004/005644 WO2004106275A2 (en) 2003-05-30 2004-05-26 Compounds useful in the therapy of alzheimer’s disease and formulations containing them

Publications (1)

Publication Number Publication Date
ECSP056190A true ECSP056190A (es) 2006-08-30

Family

ID=30131121

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2005006190A ECSP056190A (es) 2003-05-30 2005-11-28 Compuestos utiles en la terapia de la enfermedad de alzheimer y formulaciones que los contienen

Country Status (16)

Country Link
US (1) US20070010507A1 (es)
EP (1) EP1638914A2 (es)
JP (1) JP2007505152A (es)
KR (1) KR20060012316A (es)
CN (1) CN1795158A (es)
AU (1) AU2004242838A1 (es)
BR (1) BRPI0410703A (es)
CA (1) CA2527354A1 (es)
DE (1) DE602004010100T2 (es)
EC (1) ECSP056190A (es)
IL (1) IL172213A0 (es)
IT (1) ITMI20031098A1 (es)
MX (1) MXPA05012826A (es)
NO (1) NO20056042L (es)
RU (1) RU2005136984A (es)
WO (1) WO2004106275A2 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060287554A1 (en) * 2005-06-21 2006-12-21 Madsen Kevin K Process for producing inorganic salts of hop acids
WO2007035941A2 (en) * 2005-09-23 2007-03-29 Alza Corporation Transdermal galantamine delivery system
EP2236160A3 (en) * 2009-03-31 2011-12-14 Sanovel Ilac Sanayi ve Ticaret A.S. Modified release dimebolin formulations
CA2776498A1 (en) * 2009-10-02 2011-04-07 Blanchette Rockefeller Neurosciences Institute Abnormal alterations of pkc isozymes processing in alzheimer's disease peripheral cells
DE102010024105A1 (de) 2010-06-17 2011-12-22 Grünenthal GmbH Transdermale Verabreichung von Memantin
WO2017023791A1 (en) * 2015-07-31 2017-02-09 The Johns Hopkins University Glutamine antagonists for the treatment of cognitive deficits

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1056705B1 (de) * 1998-02-13 2003-10-29 Dr. Willmar Schwabe GmbH & Co. KG Stabile hyperforin-salze, verfahren zu ihrer herstellung und verwendung zur therapie der alzheimerschen krankheit
AU3738700A (en) * 1999-03-15 2000-10-04 Shaman Pharmaceuticals, Inc. Stabilized bicyclo(3.3.1)nonenes and methods of use
JP2005506996A (ja) * 2001-10-26 2005-03-10 メタプロテオミクス， エルエルシー シクロオキシゲナーゼ−２の発現および／または活性の相乗的阻害を示すクルクミノイド組成物

Also Published As

Publication number Publication date
US20070010507A1 (en) 2007-01-11
MXPA05012826A (es) 2006-02-13
WO2004106275A3 (en) 2005-03-17
NO20056042L (no) 2005-12-19
IL172213A0 (en) 2009-02-11
WO2004106275A2 (en) 2004-12-09
AU2004242838A1 (en) 2004-12-09
DE602004010100T2 (de) 2008-09-18
EP1638914A2 (en) 2006-03-29
ITMI20031098A1 (it) 2004-11-30
BRPI0410703A (pt) 2006-06-13
RU2005136984A (ru) 2006-03-27
CN1795158A (zh) 2006-06-28
DE602004010100D1 (de) 2007-12-27
KR20060012316A (ko) 2006-02-07
ITMI20031098A0 (it) 2003-05-30
CA2527354A1 (en) 2004-12-09
JP2007505152A (ja) 2007-03-08

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