ECSP066303A - Uso de antagonistas del receptor de angiotensina ii - Google Patents
Uso de antagonistas del receptor de angiotensina iiInfo
- Publication number
- ECSP066303A ECSP066303A EC2006006303A ECSP066303A ECSP066303A EC SP066303 A ECSP066303 A EC SP066303A EC 2006006303 A EC2006006303 A EC 2006006303A EC SP066303 A ECSP066303 A EC SP066303A EC SP066303 A ECSP066303 A EC SP066303A
- Authority
- EC
- Ecuador
- Prior art keywords
- ppargamma
- angiotensin
- inhibitor
- telmisartan
- activity
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
La invención se refiere al uso de antagonistas del receptor de la angiotensina II para el tratamiento de personas en las que se diagnosticó diabetes mellitus de tipo 2 o existe sospecha de una prediabetes, para la prevención de diabetes o para el tratamiento del síndrome metabólico y la resistencia a la insulina en pacientes con presión arterial normal.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10335027A DE10335027A1 (de) | 2003-07-31 | 2003-07-31 | Verwendung von Angiotensin II Rezeptor Antagonisten |
| DE10346260A DE10346260A1 (de) | 2003-07-31 | 2003-10-06 | Verwendung von Angiotensin II Rezeptor Antagonisten |
| DE10356815A DE10356815A1 (de) | 2003-07-31 | 2003-12-05 | Verwendung von Angiotensin II Rezeptor Antagonisten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP066303A true ECSP066303A (es) | 2006-10-25 |
Family
ID=34119379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2006006303A ECSP066303A (es) | 2003-07-31 | 2006-01-23 | Uso de antagonistas del receptor de angiotensina ii |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US20050070594A1 (es) |
| EP (3) | EP1651213B2 (es) |
| JP (1) | JP4833840B2 (es) |
| KR (1) | KR20060054404A (es) |
| CN (3) | CN1829511B (es) |
| AT (1) | ATE443519T1 (es) |
| AU (1) | AU2004260606B2 (es) |
| BR (1) | BRPI0413165A (es) |
| CA (1) | CA2534006C (es) |
| CY (1) | CY1109560T1 (es) |
| DE (4) | DE10335027A1 (es) |
| DK (2) | DK2119441T3 (es) |
| EA (2) | EA017640B1 (es) |
| EC (1) | ECSP066303A (es) |
| ES (2) | ES2543722T3 (es) |
| HU (1) | HUE027274T2 (es) |
| IL (1) | IL172693A (es) |
| ME (1) | MEP51108A (es) |
| MX (1) | MXPA06001322A (es) |
| NO (1) | NO335444B1 (es) |
| NZ (1) | NZ544877A (es) |
| PL (2) | PL2119441T3 (es) |
| PT (1) | PT1651213E (es) |
| RS (1) | RS50793B (es) |
| SI (1) | SI1651213T2 (es) |
| UA (1) | UA83854C2 (es) |
| WO (1) | WO2005011680A1 (es) |
| ZA (1) | ZA200509835B (es) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1368349B1 (de) * | 2001-02-24 | 2007-02-14 | Boehringer Ingelheim Pharma GmbH & Co.KG | Xanthinderivate, deren herstellung und deren verwendung als arzneimittel |
| US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
| US7501426B2 (en) | 2004-02-18 | 2009-03-10 | Boehringer Ingelheim International Gmbh | 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions |
| US20060078615A1 (en) * | 2004-10-12 | 2006-04-13 | Boehringer Ingelheim International Gmbh | Bilayer tablet of telmisartan and simvastatin |
| ME01615B (me) * | 2004-11-05 | 2014-09-20 | Boehringer Ingelheim Int | Dvoslojna tableta koja sadrži telmisartan i amlodipin |
| DE102004054054A1 (de) | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine |
| CN1298389C (zh) * | 2005-01-18 | 2007-02-07 | 广东省人民医院 | 一种含替米沙坦和钙离子拮抗剂的复方降压制剂及其应用 |
| WO2006136916A2 (en) * | 2005-06-20 | 2006-12-28 | Glenmark Pharmaceuticals Limited | Substantially pure micronized particles of telmisartan and pharmaceutical compositions containing same |
| DE102005035891A1 (de) | 2005-07-30 | 2007-02-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel |
| AU2006306420A1 (en) * | 2005-10-25 | 2007-05-03 | Merck Sharp & Dohme Corp. | Combination of a dipeptidyl peptidase-4 inhibitor and an anti-hypertensive agent for the treatment of diabetes and hypertension |
| RU2308947C1 (ru) * | 2006-02-26 | 2007-10-27 | Новосибирский институт органической химии им. Н.Н. Ворожцова СО РАН (НИОХ СО РАН) | Лекарственное средство с гиполипидемическим эффектом "симваглизин" |
| EP2540725A1 (de) | 2006-05-04 | 2013-01-02 | Boehringer Ingelheim International GmbH | Polymorphe von 1-((4-Methyl-chinazolin-2-yl)methyl)-3-methyl-7-(2-butin-1-yl)-8-(3-(R)-amino-piperidin-1-yl)xanthin |
| EP1852108A1 (en) * | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | DPP IV inhibitor formulations |
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| EP2051696A2 (en) * | 2006-08-18 | 2009-04-29 | Morton Grove Pharmaceuticals, Inc. | Stable liquid levetiracetam compositions and methods |
| EP1908469A1 (en) | 2006-10-06 | 2008-04-09 | Boehringer Ingelheim Vetmedica Gmbh | Angiotensin II receptor antagonist for the treatment of systemic diseases in cats |
| CN101260103A (zh) * | 2007-03-09 | 2008-09-10 | 上海艾力斯医药科技有限公司 | 一类具有部分PPARγ激动剂活性的化合物及其应用 |
| CA2682929A1 (en) * | 2007-04-17 | 2008-10-23 | Ratiopharm Gmbh | Pharmaceutical compositions comprising irbesartan |
| RU2339375C1 (ru) * | 2007-07-09 | 2008-11-27 | Илья Николаевич Медведев | Способ коррекции вазопатии при метаболическом синдроме |
| RU2345765C1 (ru) * | 2007-07-09 | 2009-02-10 | Илья Николаевич Медведев | Способ коррекции гиперфибриногенемии при метаболическом синдроме |
| RU2344818C1 (ru) * | 2007-07-09 | 2009-01-27 | Илья Николаевич Медведев | СПОСОБ НОРМАЛИЗАЦИИ УРОВНЯ α2-АНТИПЛАЗМИНА ПРИ МЕТАБОЛИЧЕСКОМ СИНДРОМЕ |
| RU2345767C1 (ru) * | 2007-07-09 | 2009-02-10 | Илья Николаевич Медведев | Способ быстрой нормализации эндотелиоцитемии при метаболическом синдроме |
| PE20091730A1 (es) | 2008-04-03 | 2009-12-10 | Boehringer Ingelheim Int | Formulaciones que comprenden un inhibidor de dpp4 |
| RU2387449C1 (ru) * | 2008-08-05 | 2010-04-27 | Государственное образовательное учреждение дополнительного профессионального образования Санкт-Петербургская медицинская академия последипломного образования Федерального агентства по здравоохранению и социальному развитию | Способ лечения гипертензивных внутримозговых кровоизлияний |
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| BRPI0916997A2 (pt) | 2008-08-06 | 2020-12-15 | Boehringer Ingelheim International Gmbh | Inibidor de dpp-4 e seu uso |
| CN102149407A (zh) | 2008-09-10 | 2011-08-10 | 贝林格尔.英格海姆国际有限公司 | 治疗糖尿病和相关病症的组合疗法 |
| US20200155558A1 (en) | 2018-11-20 | 2020-05-21 | Boehringer Ingelheim International Gmbh | Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug |
| CN102256976A (zh) | 2008-12-23 | 2011-11-23 | 贝林格尔.英格海姆国际有限公司 | 有机化合物的盐形式 |
| AR074990A1 (es) | 2009-01-07 | 2011-03-02 | Boehringer Ingelheim Int | Tratamiento de diabetes en pacientes con un control glucemico inadecuado a pesar de la terapia con metformina |
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| KR20240090632A (ko) | 2009-11-27 | 2024-06-21 | 베링거 인겔하임 인터내셔날 게엠베하 | 리나글립틴과 같은 dpp-iv 억제제를 사용한 유전자형 검사된 당뇨병 환자의 치료 |
| RU2422141C1 (ru) * | 2010-02-15 | 2011-06-27 | Илья Николаевич Медведев | Способ нормализации функциональной активности стенки сосудов у больных артериальной гипертонией i-ii степени при метаболическом синдроме, перенесших тромбоз сосудов глаза |
| RU2423126C1 (ru) * | 2010-02-15 | 2011-07-10 | Илья Николаевич Медведев | Способ коррекции функций стенки сосудов у больных артериальной гипертонией i-ii степени при метаболическом синдроме, перенесших тромбоз сосудов глаза |
| RU2423125C1 (ru) * | 2010-02-15 | 2011-07-10 | Илья Николаевич Медведев | Способ нивелирования дисфункций сосудистой стенки у больных артериальной гипертонией iii степени при метаболическом синдроме, перенесших тромбоз сосудов глаза |
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| JP6224084B2 (ja) | 2012-05-14 | 2017-11-01 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 糸球体上皮細胞関連障害及び/又はネフローゼ症候群の治療に用いるdpp−4阻害薬としてのキサンチン誘導体 |
| WO2013174767A1 (en) | 2012-05-24 | 2013-11-28 | Boehringer Ingelheim International Gmbh | A xanthine derivative as dpp -4 inhibitor for use in modifying food intake and regulating food preference |
| EP3110449B1 (en) | 2014-02-28 | 2023-06-28 | Boehringer Ingelheim International GmbH | Medical use of a dpp-4 inhibitor |
| CN109310697A (zh) | 2016-06-10 | 2019-02-05 | 勃林格殷格翰国际有限公司 | 利格列汀和二甲双胍的组合 |
| RU2699508C1 (ru) * | 2018-07-25 | 2019-09-05 | Федеральное государственное бюджетное образовательное учреждение высшего образования "Северо-Осетинская государственная медицинская академия" Министерства здравоохранения Российской Федерации | Способ лечения больных метаболическим синдромом |
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2003
- 2003-07-31 DE DE10335027A patent/DE10335027A1/de not_active Withdrawn
- 2003-10-06 DE DE10346260A patent/DE10346260A1/de not_active Withdrawn
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2004
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- 2004-07-24 BR BRPI0413165-7A patent/BRPI0413165A/pt active Search and Examination
- 2004-07-24 DK DK09160568.3T patent/DK2119441T3/en active
- 2004-07-24 CN CN2010102582634A patent/CN101926997A/zh active Pending
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- 2004-07-24 WO PCT/EP2004/008326 patent/WO2005011680A1/de not_active Ceased
- 2004-07-24 MX MXPA06001322A patent/MXPA06001322A/es active IP Right Grant
- 2004-07-24 SI SI200431301T patent/SI1651213T2/sl unknown
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- 2004-07-24 UA UAA200601929A patent/UA83854C2/uk unknown
- 2004-07-24 AU AU2004260606A patent/AU2004260606B2/en not_active Revoked
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- 2004-07-24 EP EP04763484A patent/EP1651213B2/de not_active Revoked
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- 2004-07-24 CN CN2011100821828A patent/CN102139110A/zh active Pending
- 2004-07-24 EP EP10177920.5A patent/EP2263670B1/de not_active Revoked
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- 2004-07-24 DE DE502004010117T patent/DE502004010117D1/de not_active Expired - Lifetime
- 2004-07-24 KR KR1020067002186A patent/KR20060054404A/ko not_active Ceased
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- 2004-07-24 AT AT04763484T patent/ATE443519T1/de active
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