ECSP077247A - Trans - clomifeno para el tratamiento de la hipertrofia prostatica benigna, cancer prostatico, hipogonodismo, trigliceridos elevados y alto colesterol - Google Patents

Trans - clomifeno para el tratamiento de la hipertrofia prostatica benigna, cancer prostatico, hipogonodismo, trigliceridos elevados y alto colesterol

Info

Publication number
ECSP077247A
ECSP077247A EC2007007247A ECSP077247A ECSP077247A EC SP077247 A ECSP077247 A EC SP077247A EC 2007007247 A EC2007007247 A EC 2007007247A EC SP077247 A ECSP077247 A EC SP077247A EC SP077247 A ECSP077247 A EC SP077247A
Authority
EC
Ecuador
Prior art keywords
trans
treatment
triglicerids
hypogonodism
clomphene
Prior art date
Application number
EC2007007247A
Other languages
English (en)
Inventor
Joseph Podolski
Ronald Wiehle
Original Assignee
Repros Therapeutis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Repros Therapeutis Inc filed Critical Repros Therapeutis Inc
Publication of ECSP077247A publication Critical patent/ECSP077247A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Composiciones que comprenden trans-clomifeno pueden ser útiles en el tratamiento de hipertrofia benigna de la próstata, cáncer de próstata, niveles elevados de triglicéridos e hipogonadismo
EC2007007247A 2004-07-14 2007-02-14 Trans - clomifeno para el tratamiento de la hipertrofia prostatica benigna, cancer prostatico, hipogonodismo, trigliceridos elevados y alto colesterol ECSP077247A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US58813004P 2004-07-14 2004-07-14
US58812304P 2004-07-14 2004-07-14
US58822304P 2004-07-14 2004-07-14

Publications (1)

Publication Number Publication Date
ECSP077247A true ECSP077247A (es) 2007-03-29

Family

ID=35134086

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2007007247A ECSP077247A (es) 2004-07-14 2007-02-14 Trans - clomifeno para el tratamiento de la hipertrofia prostatica benigna, cancer prostatico, hipogonodismo, trigliceridos elevados y alto colesterol

Country Status (6)

Country Link
US (1) US20080242726A1 (es)
EP (1) EP1776098A1 (es)
BR (1) BRPI0513129A (es)
EC (1) ECSP077247A (es)
MX (1) MX2007000050A (es)
WO (1) WO2006019916A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2312593T3 (es) 2001-07-09 2009-03-01 Repros Therapeutics Inc. Procedimientos y materiales para el tratamiento de la deficiencia de testosterona en hombres.
US7737185B2 (en) 2001-07-09 2010-06-15 Repros Therapeutics Inc. Methods and compositions with trans-clomiphene
KR20070114187A (ko) 2005-03-22 2007-11-29 레프로스 쎄라피우틱스 아이엔씨. 트랜스-클로미펜의 투약 방법
BRPI0818637A2 (pt) * 2007-10-16 2015-04-07 Repros Therapeutics Inc Métodos de tratamento de sintoma da síndrome metabólica, de glicose em jejum prejudicada, da síndrome metabólica e de redução de níveis de glicose em, jejum em sujeito com hipogonadismo hipogonadotrófico secundário ou idiopático
UA113291C2 (xx) 2011-08-04 2017-01-10 Метаболіти транскломіфену і їх застосування
UA113324C2 (xx) 2012-08-21 2017-01-10 Склади транс-кломіфену та їх застосування
CA2889770A1 (en) * 2012-11-02 2014-05-08 Repros Therapeutics Inc. Trans-clomiphene for use in cancer therapy
US20160051495A1 (en) * 2014-08-20 2016-02-25 Professional Compounding Centers Of America Oral Transmucosal Compositions including C-SERMs for Low Testosterone Levels in Men
KR20180112048A (ko) * 2016-02-25 2018-10-11 아스펜 파크 파마슈티컬스 인코포레이티드 클로미펜 이성질체들의 경구 제형 및 이차 생식선 기능저하증 치료를 위하여 이들을 사용하는 방법
CN108420806A (zh) * 2017-02-15 2018-08-21 武汉华杰世纪生物医药有限公司 具有靶向性的抗肿瘤药物

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4061733A (en) * 1976-10-15 1977-12-06 Narayan Vishwanath Gunjikar Veterinary compositions for inducing estrus in animals and method
US4729999A (en) * 1984-10-12 1988-03-08 Bcm Technologies Antiestrogen therapy for symptoms of estrogen deficiency
US4820736A (en) * 1987-03-20 1989-04-11 Yale University Use of clomiphene to predict fertility in a human female
US5580578A (en) * 1992-01-27 1996-12-03 Euro-Celtique, S.A. Controlled release formulations coated with aqueous dispersions of acrylic polymers
US5681585A (en) * 1991-12-24 1997-10-28 Euro-Celtique, S.A. Stabilized controlled release substrate having a coating derived from an aqueous dispersion of hydrophobic polymer
US5776923A (en) * 1993-01-19 1998-07-07 Endorecherche, Inc. Method of treating or preventing osteoporosis by adminstering dehydropiandrosterone
GB9405304D0 (en) * 1994-03-16 1994-04-27 Scherer Ltd R P Delivery systems for hydrophobic drugs
DE4435368A1 (de) * 1994-09-22 1996-03-28 Schering Ag Verwendung von Aromatasehemmern zur Herstellung eines Arzneimittels zur Behandlung eines relativen Androgenmangels beim Mann
WO1997006787A2 (en) * 1995-08-17 1997-02-27 Dyer, Alison, Margaret Controlled release products
US5773031A (en) * 1996-02-27 1998-06-30 L. Perrigo Company Acetaminophen sustained-release formulation
IL120262A (en) * 1996-02-28 2001-01-28 Pfizer Droloxifene and derivatives thereof for use in increasing serum testosterone levels
DE69730982T2 (de) * 1996-10-28 2005-09-01 General Mills, Inc., Minneapolis Einbettung und einkapselung von teilchen zur kontrollierten abgabe
US6322797B1 (en) * 1997-04-03 2001-11-27 Guilford Pharmaceuticals, Inc. Biodegradable terephthalate polyester-poly (phosphate) polymers, compositions, articles, and methods for making and using the same
US6653297B1 (en) * 1997-07-03 2003-11-25 Medical College Of Hampton Roads Control of selective estrogen receptor modulators
US6342250B1 (en) * 1997-09-25 2002-01-29 Gel-Del Technologies, Inc. Drug delivery devices comprising biodegradable protein for the controlled release of pharmacologically active agents and method of making the drug delivery devices
US6413533B1 (en) * 1998-05-07 2002-07-02 The University Of Tennessee Research Corporation Method for chemoprevention of prostate cancer
EP1102753B1 (en) * 1998-08-07 2007-02-28 Novartis Vaccines and Diagnostics, Inc. Pyrazoles as estrogen receptor modulators
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
CN1220491C (zh) * 1999-06-11 2005-09-28 沃特森药物公司 非口服雄激素类固醇用于制备改善性激素结合球蛋白水平升高的药物
AU6132700A (en) * 1999-09-30 2001-04-05 Chienna B.V. Polymers loaded with bioactive agents
WO2001052823A2 (en) * 2000-01-20 2001-07-26 Noven Pharmaceuticals, Inc. Compositions to effect the release profile in the transdermal administration of drugs
WO2001091744A1 (en) * 2000-05-26 2001-12-06 Harry Fisch Methods of treating androgen deficiency in men using selective antiestrogens
US7067557B2 (en) * 2000-05-26 2006-06-27 Harry Fisch Methods of treating androgen deficiency in men using selective antiestrogens
WO2002008546A1 (de) * 2000-07-22 2002-01-31 Hubertus Greschbach Modul zum aufbau von plattformen
US6503894B1 (en) * 2000-08-30 2003-01-07 Unimed Pharmaceuticals, Inc. Pharmaceutical composition and method for treating hypogonadism
US6743448B2 (en) * 2000-12-11 2004-06-01 Abraham H. Kryger Topical testosterone formulations and associated methods
US7173064B2 (en) * 2001-07-09 2007-02-06 Repros Therapeutics Inc. Methods and compositions with trans-clomiphene for treating wasting and lipodystrophy
ES2312593T3 (es) * 2001-07-09 2009-03-01 Repros Therapeutics Inc. Procedimientos y materiales para el tratamiento de la deficiencia de testosterona en hombres.
US6645974B2 (en) * 2001-07-31 2003-11-11 Merck & Co., Inc. Androgen receptor modulators and methods for use thereof
US20060269611A1 (en) * 2001-11-29 2006-11-30 Steiner Mitchell S Prevention and treatment of androgen-deprivation induced osteoporosis
US7105679B2 (en) * 2001-12-19 2006-09-12 Kanojia Ramesh M Heteroatom containing tetracyclic derivatives as selective estrogen receptor modulators

Also Published As

Publication number Publication date
US20080242726A1 (en) 2008-10-02
EP1776098A1 (en) 2007-04-25
WO2006019916A1 (en) 2006-02-23
MX2007000050A (es) 2007-07-10
BRPI0513129A (pt) 2008-04-29

Similar Documents

Publication Publication Date Title
ECSP077247A (es) Trans - clomifeno para el tratamiento de la hipertrofia prostatica benigna, cancer prostatico, hipogonodismo, trigliceridos elevados y alto colesterol
EP1887976B8 (en) Devices for treating benign prostatic hyperplasia and other conditions
AR054667A1 (es) Composicion hemostatica que comprende acido hialuronico
CL2007001269A1 (es) Compuestos derivados de heterociclos de nitrogeno, moduladores de vias de hedgehog; y uso para el tratamiento de cancer pancreatico, cancer de prostata, meduloblastoma, carcinoma celular basal y cancer pulmonar de celula pequena.
CL2012002844A1 (es) Compuestos derivados de cromen-2-ona; composicion farmaceutica que los comprende; y su uso en el tratamiento de un trastorno proliferativo de celulas tal como cancer (divisional solicitud nº 311-07).
WO2012018404A3 (en) Use of her3 binding agents in prostate treatment
GEP20074122B (en) Treating benign prostate hyperplasia with selective androgen receptor modulators
CO6311078A2 (es) Compuestos heterociclicos que contienen dos o más heteroanillos, que contienen átomos de nitrogeno como únicos heteroátomos en el anillo, en donde al menos un anillo es de 6 miembros con un átomo de nitrógeno, que contienen tres ó más heteroátomos, c
WO2008128169A8 (en) Sparc and methods of use thereof
CY1113137T1 (el) Παραγωγα πυριμιδινυλ-πυριδαζινονης
WO2007149287A3 (en) Transfer factor compositions and methods
SV2009003227A (es) Composiciones de inhibidores de chk 1 ref. x-17672
CL2012000623A1 (es) Compuestos derivados de 4-[4,4-dimetil-5oxo-3-(piridin-ilmetil)-2-tioxoimidazolidin-1-il]-2-(trifluorometil)benzonitrilo, con propiedades antiandrogenicas; metodo de preparacion; composcion farmaceutica; y su uso para el tratamiento y/o profilaxis de cancer de prostata.
EP1906947A4 (en) LIGHT-SENSITIVE COMPOSITION AND ITS USES
CU23784B7 (es) Bencimidazoles sustituidos como inhibidores de cinasa
CL2007002953A1 (es) Compuestos derivados de espiro-oxindol; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto en el tratamiento del dolor, cancer, prurito, hiperplasia prostatica benigna, hipercolesterolemia.
UY32769A (es) Composición para el tratamiento de la hiperplasia prostática benigna
MY160041A (en) Compositions and methods for treating parasitic infections
WO2007051065A3 (en) Compositions and treatments for inhibiting kinase and/or hmg-coa reductase
AR059203A1 (es) Composiciones para uso vaginal
NZ579478A (en) Epha3 antibodies for the treatment of solid tumors
WO2002030465A3 (en) Compositions that inhibit proliferation of cancer cells
BRPI0514586A (pt) triazolftalazinas
ECSP077333A (es) Compuestos de 4-amino-sustituido-2-sustituido-1,2,3,4-tetrahidroquinolina
MX2008002057A (es) Complejo de inclusion del inhibidor del factor xa con ciclodextrina.