ECSP088489A - SULFAMOIL SULFONATE PRODUCTS - Google Patents
SULFAMOIL SULFONATE PRODUCTSInfo
- Publication number
- ECSP088489A ECSP088489A EC2008008489A ECSP088489A ECSP088489A EC SP088489 A ECSP088489 A EC SP088489A EC 2008008489 A EC2008008489 A EC 2008008489A EC SP088489 A ECSP088489 A EC SP088489A EC SP088489 A ECSP088489 A EC SP088489A
- Authority
- EC
- Ecuador
- Prior art keywords
- sulfamoil
- production
- sulfonate products
- sulfonate
- products
- Prior art date
Links
- BDHFUVZGWQCTTF-UHFFFAOYSA-M sulfonate Chemical compound [O-]S(=O)=O BDHFUVZGWQCTTF-UHFFFAOYSA-M 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000003846 Carbonic anhydrases Human genes 0.000 abstract 1
- 108090000209 Carbonic anhydrases Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- UYSRSLSTXYYNEW-UHFFFAOYSA-N NS(=O)(=O)S(O)(=O)=O Chemical compound NS(=O)(=O)S(O)(=O)=O UYSRSLSTXYYNEW-UHFFFAOYSA-N 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008177 pharmaceutical agent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0072—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the A ring of the steroid being aromatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Abstract
Esta invención se relaciona con prodrogas de sulfonato de sulfamoilo de fórmula general I, con un proceso para su producción, con composiciones farmacéuticas que contienen estos compuestos, y con su uso para la producción de agentes farmacéuticos disponibles por vía oral.Los compuestos de acuerdo a la invención se unen a anhidrasas carbónicas e inhiben a estas enzimas.This invention relates to sulfamoyl sulfonate prodrugs of general formula I, a process for their production, pharmaceutical compositions containing these compounds, and their use for the production of orally available pharmaceutical agents.The compounds according to The invention binds carbonic anhydrases and inhibits these enzymes.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102005057408A DE102005057408A1 (en) | 2005-11-30 | 2005-11-30 | New sulfamoylsulfonate prodrugs e.g. useful for protecting red blood cells from attack by parasites or for hormone replacement therapy, female fertility control or treating hormone-associated diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP088489A true ECSP088489A (en) | 2008-06-30 |
Family
ID=37983623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2008008489A ECSP088489A (en) | 2005-11-30 | 2008-05-30 | SULFAMOIL SULFONATE PRODUCTS |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1957513A2 (en) |
| JP (1) | JP2009517424A (en) |
| KR (1) | KR20080072956A (en) |
| CN (1) | CN101316858A (en) |
| AU (1) | AU2006319380A1 (en) |
| BR (1) | BRPI0619253A2 (en) |
| CA (1) | CA2632272A1 (en) |
| CR (1) | CR10003A (en) |
| DE (1) | DE102005057408A1 (en) |
| EA (1) | EA200801306A1 (en) |
| EC (1) | ECSP088489A (en) |
| IL (1) | IL191570A0 (en) |
| NO (1) | NO20082915L (en) |
| WO (1) | WO2007062874A2 (en) |
| ZA (1) | ZA200805659B (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8293783B2 (en) * | 2009-03-24 | 2012-10-23 | National University Of Singapore | Use of artemisinin derivatives for the treatment of asthma and chronic obstructive pulmonary disease (COPD) |
| CN101987104A (en) * | 2009-08-05 | 2011-03-23 | 天津金耀集团有限公司 | Ophthalmic composition of heteroaryl sulfamoyl carboxylic ester carbonic anhydrase inhibitor |
| CN101987101A (en) * | 2009-08-05 | 2011-03-23 | 天津金耀集团有限公司 | Anti-inflammatory eye composition with glucocorticoid aromatic sulfamoyl sulfonic acid ester as active ingredient |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10027887A1 (en) * | 2000-05-31 | 2001-12-13 | Jenapharm Gmbh | Compounds with a sulfonamide group and pharmaceutical compositions containing these compounds |
| DE102004025966A1 (en) * | 2004-05-21 | 2005-12-15 | Schering Ag | Estradiol prodrugs |
| DE102004025985A1 (en) * | 2004-05-21 | 2005-12-15 | Schering Ag | Estriol and estetrol prodrugs |
| DE102004025986A1 (en) * | 2004-05-21 | 2005-12-15 | Schering Ag | Steroid prodrugs with androgenic effects |
-
2005
- 2005-11-30 DE DE102005057408A patent/DE102005057408A1/en not_active Ceased
-
2006
- 2006-11-27 WO PCT/EP2006/011726 patent/WO2007062874A2/en not_active Ceased
- 2006-11-27 BR BRPI0619253-0A patent/BRPI0619253A2/en not_active Application Discontinuation
- 2006-11-27 JP JP2008542678A patent/JP2009517424A/en active Pending
- 2006-11-27 AU AU2006319380A patent/AU2006319380A1/en not_active Abandoned
- 2006-11-27 CA CA002632272A patent/CA2632272A1/en not_active Abandoned
- 2006-11-27 CN CNA2006800449086A patent/CN101316858A/en active Pending
- 2006-11-27 EP EP06829354A patent/EP1957513A2/en not_active Withdrawn
- 2006-11-27 KR KR1020087015775A patent/KR20080072956A/en not_active Withdrawn
- 2006-11-27 EA EA200801306A patent/EA200801306A1/en unknown
-
2008
- 2008-05-20 IL IL191570A patent/IL191570A0/en unknown
- 2008-05-21 CR CR10003A patent/CR10003A/en not_active Application Discontinuation
- 2008-05-30 EC EC2008008489A patent/ECSP088489A/en unknown
- 2008-06-27 ZA ZA200805659A patent/ZA200805659B/en unknown
- 2008-06-27 NO NO20082915A patent/NO20082915L/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007062874B1 (en) | 2007-09-27 |
| CN101316858A (en) | 2008-12-03 |
| EP1957513A2 (en) | 2008-08-20 |
| CA2632272A1 (en) | 2007-06-07 |
| KR20080072956A (en) | 2008-08-07 |
| CR10003A (en) | 2008-08-21 |
| AU2006319380A1 (en) | 2007-06-07 |
| WO2007062874A3 (en) | 2007-07-12 |
| JP2009517424A (en) | 2009-04-30 |
| WO2007062874A2 (en) | 2007-06-07 |
| ZA200805659B (en) | 2009-10-28 |
| EA200801306A1 (en) | 2008-10-30 |
| IL191570A0 (en) | 2008-12-29 |
| DE102005057408A1 (en) | 2007-05-31 |
| BRPI0619253A2 (en) | 2011-09-27 |
| NO20082915L (en) | 2008-06-27 |
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