ECSP088501A - FORMA CRISTALINA DE 1´-(1-METILETIL)-4´-[(2-FLUORO-4-METOXIFENIL)METIL]-5´-METIL-1H-PIRAZOL-3´-O-ß-D-GLUCOPIRANÓSIDO, UN MÉTODO PARA SU PREPARACIÓN Y EL USO DE LA MISMA PARA PREPARAR MEDICAMENTOS - Google Patents

FORMA CRISTALINA DE 1´-(1-METILETIL)-4´-[(2-FLUORO-4-METOXIFENIL)METIL]-5´-METIL-1H-PIRAZOL-3´-O-ß-D-GLUCOPIRANÓSIDO, UN MÉTODO PARA SU PREPARACIÓN Y EL USO DE LA MISMA PARA PREPARAR MEDICAMENTOS

Info

Publication number
ECSP088501A
ECSP088501A EC2008008501A ECSP088501A ECSP088501A EC SP088501 A ECSP088501 A EC SP088501A EC 2008008501 A EC2008008501 A EC 2008008501A EC SP088501 A ECSP088501 A EC SP088501A EC SP088501 A ECSP088501 A EC SP088501A
Authority
EC
Ecuador
Prior art keywords
methyl
same
fluoro
preparation
methytile
Prior art date
Application number
EC2008008501A
Other languages
English (en)
Inventor
Peter Eickelmann
Leo Thomas
Gerd F Kraemer
Adil Duran
Hans-Juergen Martin
Klaus Dugi
Sabine Pinnetti
Regine Ritter
Ruediger Streicher
Gebhard Adelgoss
Gebhard Schilcher
Steffen Maier
Original Assignee
Boehringer Ingelheim International Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International Gmbh filed Critical Boehringer Ingelheim International Gmbh
Publication of ECSP088501A publication Critical patent/ECSP088501A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

La invención se refiere a una forma cristalina de 1´-(1-metiletil)-4´-[(2-fluoro-4-metoxifenil)metil]-5´-metil-1H-pirazol-3´-O-b-D-glucopiranósido, a un método para la preparación de la misma, así como al uso de la misma para preparar medicamentos.
EC2008008501A 2006-01-11 2008-06-04 FORMA CRISTALINA DE 1´-(1-METILETIL)-4´-[(2-FLUORO-4-METOXIFENIL)METIL]-5´-METIL-1H-PIRAZOL-3´-O-ß-D-GLUCOPIRANÓSIDO, UN MÉTODO PARA SU PREPARACIÓN Y EL USO DE LA MISMA PARA PREPARAR MEDICAMENTOS ECSP088501A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06000483 2006-01-11

Publications (1)

Publication Number Publication Date
ECSP088501A true ECSP088501A (es) 2008-07-30

Family

ID=35953998

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2008008501A ECSP088501A (es) 2006-01-11 2008-06-04 FORMA CRISTALINA DE 1´-(1-METILETIL)-4´-[(2-FLUORO-4-METOXIFENIL)METIL]-5´-METIL-1H-PIRAZOL-3´-O-ß-D-GLUCOPIRANÓSIDO, UN MÉTODO PARA SU PREPARACIÓN Y EL USO DE LA MISMA PARA PREPARAR MEDICAMENTOS

Country Status (19)

Country Link
US (2) US7524822B2 (es)
EP (1) EP1976859A1 (es)
JP (1) JP4936234B2 (es)
KR (1) KR20090012205A (es)
CN (1) CN101370816A (es)
AR (1) AR058962A1 (es)
AU (1) AU2007204368A1 (es)
BR (1) BRPI0706375A2 (es)
CA (1) CA2635203A1 (es)
EA (1) EA200801663A1 (es)
EC (1) ECSP088501A (es)
IL (1) IL192655A0 (es)
NO (1) NO20082395L (es)
NZ (1) NZ570311A (es)
PE (1) PE20071237A1 (es)
TW (1) TW200745149A (es)
UY (1) UY30082A1 (es)
WO (1) WO2007080170A1 (es)
ZA (1) ZA200804151B (es)

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WO2010068601A1 (en) 2008-12-08 2010-06-17 Sanofi-Aventis A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
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SG178880A1 (en) 2009-08-26 2012-04-27 Sanofi Sa Novel crystalline heteroaromatic fluoroglycoside hydrates, pharmaceuticals comprising these compounds and their use
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TW201215388A (en) 2010-07-05 2012-04-16 Sanofi Sa (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments
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WO2013037390A1 (en) 2011-09-12 2013-03-21 Sanofi 6-(4-hydroxy-phenyl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
EP2760862B1 (en) 2011-09-27 2015-10-21 Sanofi 6-(4-hydroxy-phenyl)-3-alkyl-1h-pyrazolo[3,4-b]pyridine-4-carboxylic acid amide derivatives as kinase inhibitors
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EP3082829B1 (en) 2013-12-17 2021-02-17 Boehringer Ingelheim Vetmedica GmbH Sglt2 inhibitors for the treatment of metabolic disorders in feline animals
EA032558B1 (ru) * 2014-01-23 2019-06-28 Бёрингер Ингельхайм Ветмедика Гмбх Лечение метаболических расстройств у представителей собачьих
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Also Published As

Publication number Publication date
EP1976859A1 (en) 2008-10-08
TW200745149A (en) 2007-12-16
CA2635203A1 (en) 2007-07-19
KR20090012205A (ko) 2009-02-02
EA200801663A1 (ru) 2009-02-27
JP4936234B2 (ja) 2012-05-23
UY30082A1 (es) 2007-08-31
IL192655A0 (en) 2009-02-11
US7838500B2 (en) 2010-11-23
AR058962A1 (es) 2008-03-05
PE20071237A1 (es) 2008-01-15
NO20082395L (no) 2008-07-31
NZ570311A (en) 2010-05-28
JP2009522340A (ja) 2009-06-11
US20070244176A1 (en) 2007-10-18
WO2007080170A1 (en) 2007-07-19
CN101370816A (zh) 2009-02-18
ZA200804151B (en) 2009-10-28
US20090181905A1 (en) 2009-07-16
BRPI0706375A2 (pt) 2011-03-22
US7524822B2 (en) 2009-04-28
AU2007204368A1 (en) 2007-07-19

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