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Application filed by Eisai R&D Man Co LtdfiledCriticalEisai R&D Man Co Ltd
Publication of ECSP088728ApublicationCriticalpatent/ECSP088728A/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
Se describe un compuesto representado por la fórmula (I):o una sal farmacológicamente aceptable del mismo, en donde Ar1 representa un grupo imidazolilo que puede substituirse por un grupo alquilo C1-6, o similares, Ar2 representa un grupo fenilo que puede substituirse por un grupo alcoxi C1-6, o similares, X1 representa un enlace doble o similares, y Het representa un grupo imidazolilo que puede substituirse por un grupo alquilo C1-6, o similares. El compuesto o la sal es efectivo como un agente terapéutico o profiláctico para una enfermedad asociada con Ab.A compound represented by the formula (I) is described: or a pharmacologically acceptable salt thereof, wherein Ar1 represents an imidazolyl group that can be substituted by a C1-6 alkyl group, or the like, Ar2 represents a phenyl group that can be substituted by a C1-6 alkoxy group, or the like, X1 represents a double bond or the like, and Het represents an imidazolyl group that can be substituted by a C1-6 alkyl group, or the like. The compound or salt is effective as a therapeutic or prophylactic agent for a disease associated with Ab.
NEW DERIVATIVES OF 6-TRIAZOLOPIRIDACINA-SULFANIL BENZOTIAZOL AND BENCIMIDAZOL, ITS PREPARATION PROCEDURE, ITS APPLICATION AS MEDICATIONS, PHARMACEUTICAL COMPOSITIONS AND NEW MAIN USE AS MET INHIBITORS
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