ECSP099426A - Compuestos de 4-hidroxi-2-oxo-2,3-dihidro-1,3-benzotiazol-7il para la modulación de la actividad del adrenoreceptor beta2 - Google Patents

Compuestos de 4-hidroxi-2-oxo-2,3-dihidro-1,3-benzotiazol-7il para la modulación de la actividad del adrenoreceptor beta2

Info

Publication number
ECSP099426A
ECSP099426A EC2009009426A ECSP099426A ECSP099426A EC SP099426 A ECSP099426 A EC SP099426A EC 2009009426 A EC2009009426 A EC 2009009426A EC SP099426 A ECSP099426 A EC SP099426A EC SP099426 A ECSP099426 A EC SP099426A
Authority
EC
Ecuador
Prior art keywords
compounds
benzotiazol
dihidro
hydroxi
oxo
Prior art date
Application number
EC2009009426A
Other languages
English (en)
Inventor
Alexander Charles Humphries
Stephen Connolly
Premji Meghani
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ECSP099426A publication Critical patent/ECSP099426A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/14—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01—Five-membered rings
    • C07D285/02—Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/14—Thiadiazoles; Hydrogenated thiadiazoles condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)

Abstract

La presente invención proporciona compuestos de fórmula (I) [insertar fórmula] en donde Ra, Rb, R1, R2, R3, R4, R5, R6 y R29 son tal como se definió en la descripción, procesos para su preparación, composiciones farmacéuticas que los contienen y su uso en terapia.
EC2009009426A 2006-12-20 2009-06-15 Compuestos de 4-hidroxi-2-oxo-2,3-dihidro-1,3-benzotiazol-7il para la modulación de la actividad del adrenoreceptor beta2 ECSP099426A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87092206P 2006-12-20 2006-12-20
US91004507P 2007-04-04 2007-04-04
US95198007P 2007-07-26 2007-07-26

Publications (1)

Publication Number Publication Date
ECSP099426A true ECSP099426A (es) 2009-07-31

Family

ID=39167020

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2009009426A ECSP099426A (es) 2006-12-20 2009-06-15 Compuestos de 4-hidroxi-2-oxo-2,3-dihidro-1,3-benzotiazol-7il para la modulación de la actividad del adrenoreceptor beta2

Country Status (20)

Country Link
US (3) US7700782B2 (es)
EP (1) EP2121642B1 (es)
JP (1) JP2010513440A (es)
KR (1) KR20090091342A (es)
AR (1) AR064635A1 (es)
AT (1) ATE517879T1 (es)
AU (1) AU2007336075B2 (es)
BR (1) BRPI0722096A2 (es)
CA (1) CA2672811A1 (es)
CL (1) CL2007003765A1 (es)
CO (1) CO6190554A2 (es)
EC (1) ECSP099426A (es)
IL (1) IL199014A0 (es)
MX (1) MX2009006009A (es)
NO (1) NO20092691L (es)
PE (1) PE20081544A1 (es)
SA (1) SA07280728B1 (es)
TW (1) TW200833670A (es)
UY (1) UY30808A1 (es)
WO (1) WO2008075026A1 (es)

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GB0702458D0 (en) * 2007-02-08 2007-03-21 Astrazeneca Ab Salts 668
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EA017627B1 (ru) 2008-05-13 2013-01-30 Астразенека Аб Хинуклидиновые производные в качестве антагонистов мускаринового м3 рецептора
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TW201036957A (en) 2009-02-20 2010-10-16 Astrazeneca Ab Novel salt 628
GB0913342D0 (en) 2009-07-31 2009-09-16 Astrazeneca Ab Compounds - 801
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Also Published As

Publication number Publication date
US20100249200A1 (en) 2010-09-30
US20080207698A1 (en) 2008-08-28
CL2007003765A1 (es) 2008-08-22
US7700782B2 (en) 2010-04-20
WO2008075026A1 (en) 2008-06-26
ATE517879T1 (de) 2011-08-15
KR20090091342A (ko) 2009-08-27
UY30808A1 (es) 2008-07-31
IL199014A0 (en) 2010-02-17
EP2121642B1 (en) 2011-07-27
HK1136572A1 (en) 2010-07-02
CA2672811A1 (en) 2008-06-26
PE20081544A1 (es) 2009-01-11
US20100022491A1 (en) 2010-01-28
NO20092691L (no) 2009-09-16
TW200833670A (en) 2008-08-16
AR064635A1 (es) 2009-04-15
AU2007336075A1 (en) 2008-06-26
BRPI0722096A2 (pt) 2014-04-01
CO6190554A2 (es) 2010-08-19
AU2007336075B2 (en) 2011-10-27
JP2010513440A (ja) 2010-04-30
EP2121642A1 (en) 2009-11-25
SA07280728B1 (ar) 2010-12-01
MX2009006009A (es) 2009-06-16

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