ECSP10010464A - Uso de ranolazina para el tratamiento de enfermedades cardiovasculares - Google Patents
Uso de ranolazina para el tratamiento de enfermedades cardiovascularesInfo
- Publication number
- ECSP10010464A ECSP10010464A EC2010010464A ECSP10010464A ECSP10010464A EC SP10010464 A ECSP10010464 A EC SP10010464A EC 2010010464 A EC2010010464 A EC 2010010464A EC SP10010464 A ECSP10010464 A EC SP10010464A EC SP10010464 A ECSP10010464 A EC SP10010464A
- Authority
- EC
- Ecuador
- Prior art keywords
- ranolazine
- treatment
- cardiovascular diseases
- coronary intervention
- administering
- Prior art date
Links
- XKLMZUWKNUAPSZ-UHFFFAOYSA-N N-(2,6-dimethylphenyl)-2-{4-[2-hydroxy-3-(2-methoxyphenoxy)propyl]piperazin-1-yl}acetamide Chemical compound COC1=CC=CC=C1OCC(O)CN1CCN(CC(=O)NC=2C(=CC=CC=2C)C)CC1 XKLMZUWKNUAPSZ-UHFFFAOYSA-N 0.000 title abstract 2
- 229960000213 ranolazine Drugs 0.000 title abstract 2
- 208000024172 Cardiovascular disease Diseases 0.000 title 1
- 206010003119 arrhythmia Diseases 0.000 abstract 1
- 230000006793 arrhythmia Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Se revela un método para reducir arritmias asociadas con intervención coronaria en un paciente, que comprende administrar una composición farmacéutica que comprende ranolazina antes de la intervención coronaria.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/030,468 US20090111826A1 (en) | 2007-02-13 | 2008-02-13 | Use of ranolazine for the treatment of cardiovascular diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP10010464A true ECSP10010464A (es) | 2010-10-30 |
Family
ID=40626660
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2010010464A ECSP10010464A (es) | 2008-02-13 | 2010-09-06 | Uso de ranolazina para el tratamiento de enfermedades cardiovasculares |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20090111826A1 (es) |
| EP (1) | EP2252295A1 (es) |
| JP (1) | JP2011511844A (es) |
| KR (1) | KR20110013352A (es) |
| AU (1) | AU2009214639A1 (es) |
| BR (1) | BRPI0907956A2 (es) |
| CA (1) | CA2714301A1 (es) |
| CO (1) | CO6531499A2 (es) |
| EA (1) | EA201070918A1 (es) |
| EC (1) | ECSP10010464A (es) |
| IL (1) | IL207247A0 (es) |
| MX (1) | MX2010008433A (es) |
| WO (1) | WO2009102886A1 (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8822473B2 (en) * | 2002-05-21 | 2014-09-02 | Gilead Sciences, Inc. | Method of treating diabetes |
| AU2003248558B8 (en) * | 2002-05-21 | 2009-07-09 | Gilead Sciences, Inc. | Method of treating diabetes |
| CA2689633A1 (en) * | 2007-05-31 | 2008-12-11 | Cv Therapeutics, Inc. | Use of ranolazine for elevated brain-type natriuretic peptide |
| JP2012502047A (ja) * | 2008-09-04 | 2012-01-26 | ギリアード サイエンシーズ, インコーポレイテッド | 心房細動を治療する方法 |
| MX2011012140A (es) * | 2009-05-14 | 2012-02-28 | Gilead Sciences Inc | Ranolazina para el tratamiento de problemas del snc. |
| MX2014000095A (es) * | 2011-07-07 | 2014-05-28 | Janssen Diagnostics Llc | Método de análisis de trastornos cardiovasculares y usos del mismo. |
| JP2024537585A (ja) * | 2021-09-27 | 2024-10-16 | タスリー・ファーマシューティカル・グループ・カンパニー・リミテッド | 心筋虚血の治療のための医薬組成物及びその製造方法 |
Family Cites Families (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4567264A (en) * | 1983-05-18 | 1986-01-28 | Syntex (U.S.A.) Inc. | Cardioselective aryloxy- and arylthio- hydroxypropylene-piperazinyl acetanilides which affect calcium entry |
| ES2177601T3 (es) * | 1989-06-23 | 2002-12-16 | Syntex Llc | Ranolazina y pepeerazinas relacionadas para uso en el tratamiento de estados de choque. . |
| US5455045A (en) * | 1993-05-13 | 1995-10-03 | Syntex (U.S.A.) Inc. | High dose formulations |
| US20030077229A1 (en) * | 1997-10-01 | 2003-04-24 | Dugger Harry A. | Buccal, polar and non-polar spray or capsule containing cardiovascular or renal drugs |
| US6541479B1 (en) * | 1997-12-02 | 2003-04-01 | Massachusetts College Of Pharmacy | Calcium channel blockers |
| US6897305B2 (en) * | 1998-06-08 | 2005-05-24 | Theravance, Inc. | Calcium channel drugs and uses |
| US6303607B1 (en) * | 1998-09-10 | 2001-10-16 | Cv Therapeutics, Inc. | Method for administering a sustained release ranolanolazine formulation |
| US6479496B1 (en) * | 1998-09-10 | 2002-11-12 | Cv Therapeutics, Inc. | Methods for treating angina with ranolazine |
| US20050245502A1 (en) * | 1999-08-23 | 2005-11-03 | Phoenix Biosciences | Treatments for viral infections |
| US6734192B1 (en) * | 1999-08-23 | 2004-05-11 | Mp-1 Inc. | Treatment of viral infections |
| US6803457B1 (en) * | 1999-09-30 | 2004-10-12 | Pfizer, Inc. | Compounds for the treatment of ischemia |
| NZ520780A (en) * | 2000-02-18 | 2006-04-28 | Cv Therapeutics Inc | Partial fatty acid oxidation inhibitors in the treatment of congestive heart failure |
| US20030220312A1 (en) * | 2000-05-11 | 2003-11-27 | G.D. Searle & Co. | Epoxy-steroidal aldosterone antagonist and calcium channel blocker combination therapy for treatment of cardiovascular disorders |
| WO2002007716A2 (en) * | 2000-07-21 | 2002-01-31 | Cv Therapeutics, Inc. | Method for treating angina |
| ATE357257T1 (de) * | 2000-07-27 | 2007-04-15 | Pharmacia Corp | Kombinationstherapie mit epoxy-steroidalen aldosteronantagonisten und kalziumkanalblocker zur behandlung von kongestivem herzversagen |
| GB0028414D0 (en) * | 2000-11-22 | 2001-01-03 | Univ Leeds | Flush preservation solution |
| IL147696A0 (en) * | 2001-01-25 | 2002-08-14 | Pfizer Prod Inc | Combination therapy |
| US6423705B1 (en) * | 2001-01-25 | 2002-07-23 | Pfizer Inc. | Combination therapy |
| EP1385548B1 (en) * | 2001-01-26 | 2007-05-23 | Schering Corporation | Combinations of sterol absorption inhibitor(s) with cardiovascular agent(s) for the treatment of vascular conditions |
| US20030220310A1 (en) * | 2001-07-27 | 2003-11-27 | Schuh Joseph R. | Epoxy-steroidal aldosterone antagonist and calcium channel blocker combination therapy for treatment of congestive heart failure |
| US20050250676A1 (en) * | 2001-11-19 | 2005-11-10 | Aventis Pharma Deutschland Gmbh | Method of activating insulin receptor substrate-2 to stimulate insulin production |
| US6958352B2 (en) * | 2002-02-08 | 2005-10-25 | Smithkline Beecham Corporation | Compounds for inhibiting insulin secretion and methods related thereto |
| CN1911460A (zh) * | 2002-02-15 | 2007-02-14 | Cv医药有限公司 | 用于医用装置的聚合物涂层 |
| US20030220344A1 (en) * | 2002-04-04 | 2003-11-27 | Luiz Belardinelli | Method of treating arrhythmias |
| AU2003248558B8 (en) * | 2002-05-21 | 2009-07-09 | Gilead Sciences, Inc. | Method of treating diabetes |
| WO2004079372A1 (en) * | 2003-03-05 | 2004-09-16 | Metabolex Inc. | Methods and compositions for treating and diagnosing diabetes and related diseases involving beta-trp |
| AU2004248187A1 (en) * | 2003-06-12 | 2004-12-23 | University Of Colorado System Technology | Systems and methods for treating human inflammatory and proliferative diseases and wounds, with fatty acid metabolism inhibitors and/or glycolytic inhibitors |
| US20050074425A1 (en) * | 2003-07-02 | 2005-04-07 | Polycord, Inc. | Method for delivering polymerized therapeutic agent compositions and compositions thereof |
| US7060723B2 (en) * | 2003-08-29 | 2006-06-13 | Allergan, Inc. | Treating neurological disorders using selective antagonists of persistent sodium current |
| ES2258365B1 (es) * | 2003-10-03 | 2007-12-01 | Lacer, S.A. | Derivados de disulfuro, sulfuro, sulfoxido y sulfona de azucares ciclicos y sus usos. |
| WO2005070126A2 (en) * | 2004-01-08 | 2005-08-04 | The Regents Of The University Of Colorado | Methods and compositions for treating human diseases and wounds with ucp and fas inhibitors |
| CA2568134A1 (en) * | 2004-05-24 | 2005-12-08 | New York University | Method of treating or preventing pathologic effects of acute increases in hyperglycemia and/or acute increases of free fatty acid flux |
| MX2007005367A (es) * | 2004-11-09 | 2007-06-18 | Cv Therapeutics Inc | Uso de ranolazina en combinacion con por lo menos un agente de remodelacion para revertir la remodelacion ventricular izquierda en el tratamiento de la insuficiencia cardiaca. |
| MX2007008162A (es) * | 2005-01-06 | 2007-07-24 | Cv Therapeutics Inc | Formulaciones farmaceuticas de liberacion prolongada que contienen ranolazina. |
| US20060205727A1 (en) * | 2005-03-11 | 2006-09-14 | Wayne Kaesemeyer | Combination therapy for endothelial dysfunction, angina and diabetes |
| US20080153840A1 (en) * | 2006-12-21 | 2008-06-26 | Luiz Belardinelli | Reduction of cardiovascular symptoms |
| EP2117549A1 (en) * | 2007-02-13 | 2009-11-18 | CV Therapeutics Inc. | Use of ranolazine for the treatment of coronary microvascular diseases |
| JP2010518171A (ja) * | 2007-02-13 | 2010-05-27 | ギリアード・パロ・アルト・インコーポレイテッド | 非冠微小血管疾患の処置のためのラノラジンの使用 |
| CA2678272A1 (en) * | 2007-02-13 | 2008-10-02 | Cv Therapeutics, Inc. | Use of ranolazine for the treatment of cardiovascular diseases |
| WO2008116083A1 (en) * | 2007-03-22 | 2008-09-25 | Cv Therapeutics, Inc. | Use of ranolazine for elevated brain-type natriuretic peptide |
| JP2010528112A (ja) * | 2007-05-31 | 2010-08-19 | ギリアード・パロ・アルト・インコーポレイテッド | 糖尿病を治療する方法 |
| CA2689633A1 (en) * | 2007-05-31 | 2008-12-11 | Cv Therapeutics, Inc. | Use of ranolazine for elevated brain-type natriuretic peptide |
-
2008
- 2008-02-13 US US12/030,468 patent/US20090111826A1/en not_active Abandoned
-
2009
- 2009-02-12 WO PCT/US2009/033950 patent/WO2009102886A1/en not_active Ceased
- 2009-02-12 KR KR1020107019766A patent/KR20110013352A/ko not_active Withdrawn
- 2009-02-12 MX MX2010008433A patent/MX2010008433A/es not_active Application Discontinuation
- 2009-02-12 CA CA2714301A patent/CA2714301A1/en not_active Abandoned
- 2009-02-12 BR BRPI0907956-4A patent/BRPI0907956A2/pt not_active IP Right Cessation
- 2009-02-12 AU AU2009214639A patent/AU2009214639A1/en not_active Abandoned
- 2009-02-12 EP EP09711382A patent/EP2252295A1/en not_active Withdrawn
- 2009-02-12 JP JP2010546897A patent/JP2011511844A/ja not_active Withdrawn
- 2009-02-12 EA EA201070918A patent/EA201070918A1/ru unknown
- 2009-10-15 US US12/579,956 patent/US20100035890A1/en not_active Abandoned
-
2010
- 2010-07-27 IL IL207247A patent/IL207247A0/en unknown
- 2010-08-11 CO CO10098708A patent/CO6531499A2/es not_active Application Discontinuation
- 2010-09-06 EC EC2010010464A patent/ECSP10010464A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EA201070918A1 (ru) | 2011-02-28 |
| KR20110013352A (ko) | 2011-02-09 |
| EP2252295A1 (en) | 2010-11-24 |
| US20090111826A1 (en) | 2009-04-30 |
| CA2714301A1 (en) | 2009-08-20 |
| WO2009102886A1 (en) | 2009-08-20 |
| MX2010008433A (es) | 2011-03-02 |
| US20100035890A1 (en) | 2010-02-11 |
| AU2009214639A1 (en) | 2009-08-20 |
| JP2011511844A (ja) | 2011-04-14 |
| CO6531499A2 (es) | 2012-09-28 |
| IL207247A0 (en) | 2010-12-30 |
| BRPI0907956A2 (pt) | 2015-08-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CL2016002589A1 (es) | Uso del compuesto genz-112638 (eliglustat), inhibidor de glucosilceramida sintasa, en el tratamiento de la enfermedad de gaucher y enfermedad de fabry (divisional de solicitud 201201348). | |
| CO6531499A2 (es) | Uso de ranolazina para el tratameinto de enfermedades cardiovasculares | |
| PA8794401A1 (es) | Acidos 6-fenilnicotinicos sustituidos y su uso | |
| CO6440531A2 (es) | 2-acetamido-5-aril-1,2,4-triazolonas sustituidas y su uso | |
| BRPI0911273B8 (pt) | composição farmacêutica compreendendo um inibidor de dpp-iv, bem como processo para sua preparação | |
| ECSP099436A (es) | Acilaminopirazoles como inhibidores de fgfr | |
| CL2011003266A1 (es) | Compuestos derivados de imidazolidin-2-ona, con actividad inhibidora de 17alfa-hidroxilasa/liasa-c17,20; composicion farmaceutica que los comprende; y uso en el tratamiento de inflamacion o cancer, entre otras. | |
| GT200900230A (es) | 4-aril-1,4-dihidro-1,6-naftiridinamidas sustituidas y uso | |
| UY31228A1 (es) | Ariloxazoles sustituidos y su uso | |
| CL2008002999A1 (es) | Uso de una composicion farmeceutica que comprende trns-clominefo para preparar un medicamenteo util en el ratamiento de recuccion de los niveles de glucosa en ayunas en un varon. | |
| DOP2007000043A (es) | Derivados de cromanol sustituidos y su uso | |
| CL2008002049A1 (es) | Compuestos derivados de aminoindol macrociclicos; composicion farmaceutica que comprende a dicho compuesto; y uso del compuesto para el tratamiento de la hepatitis c. | |
| CL2007003643A1 (es) | Composicion farmaceutica de azimilidina que comprende 0,5% a aproximadamente 2,5% (w/w) de agua; y uso para el tratamiento de arritmias cardiacas. | |
| UY32414A (es) | Nuevos metodos | |
| UY30582A1 (es) | Derivados de acido 2-fenoxinicotinico y su uso | |
| CO6311076A2 (es) | Una composición que comprende 2-n-butil-3-[4-(3-di-n-butilaminopropoxi)benzoil]-5-metilsulfonamido-benzofurano y sus sales aceptables farmacéuticamente | |
| CR11869A (es) | 7-sulfanilmetil-, 7-sulfinilmetil- y 7-sulfonilmetilindoles sustituidos y el uso de los mismos | |
| CL2008000965A1 (es) | Composicion farmaceutica que comprende un agente antiinflamatorio no esteroideo y un analgesico opiaceo, y su uso para el tratamiento del dolor. | |
| CO6551684A2 (es) | Uso de una fuente de l3 y/o l5 como vacuna o como diagnóstico para una enfermedad parasitaria | |
| CO6541630A2 (es) | Combinación teobromina con un descongestivo y su uso para el tratamiento de la tos | |
| ES2578729T3 (es) | Agente terapéutico para enfermedades relacionadas con el hígado | |
| CL2008002465A1 (es) | Composición farmacéutica anhidra tópica, que comprende derivados de niacina y un portador aceptable, su aplicacón permite un bienestar sexual mejorado. | |
| AR082594A1 (es) | Docosahexanoato de pantenilo y su uso para el tratamiento y prevencion de enfermedades cardiovasculares | |
| AR067351A1 (es) | Combinacion de picotamida con nafronil | |
| BRPI0607976A2 (pt) | composição farmacêutica e uso de uma composição |