ECSP11011053A - [4-(1-amino-etil)-ciclohexil]-metil-aminas como antibacterianos - Google Patents

[4-(1-amino-etil)-ciclohexil]-metil-aminas como antibacterianos

Info

Publication number
ECSP11011053A
ECSP11011053A EC2011011053A ECSP11011053A ECSP11011053A EC SP11011053 A ECSP11011053 A EC SP11011053A EC 2011011053 A EC2011011053 A EC 2011011053A EC SP11011053 A ECSP11011053 A EC SP11011053A EC SP11011053 A ECSP11011053 A EC SP11011053A
Authority
EC
Ecuador
Prior art keywords
ciclohexil
aminas
etil
metil
antibacterials
Prior art date
Application number
EC2011011053A
Other languages
English (en)
Inventor
Folkert Reck
Mark Cronin
Bolin Geng
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ECSP11011053A publication Critical patent/ECSP11011053A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La presente invención se refiere a compuestos de Fórmula (I); y sales farmacéuticamente aceptables de los mismos, a su uso en el tratamiento de infecciones bacterianas y a sus métodos de preparación.
EC2011011053A 2008-11-14 2011-05-13 [4-(1-amino-etil)-ciclohexil]-metil-aminas como antibacterianos ECSP11011053A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11470608P 2008-11-14 2008-11-14
US16384809P 2009-03-26 2009-03-26

Publications (1)

Publication Number Publication Date
ECSP11011053A true ECSP11011053A (es) 2011-06-30

Family

ID=41463108

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2011011053A ECSP11011053A (es) 2008-11-14 2011-05-13 [4-(1-amino-etil)-ciclohexil]-metil-aminas como antibacterianos

Country Status (20)

Country Link
US (1) US20110288084A1 (es)
EP (1) EP2370444A1 (es)
JP (1) JP2012508789A (es)
KR (1) KR20110093797A (es)
CN (1) CN102216308A (es)
AR (1) AR074340A1 (es)
AU (1) AU2009315425A1 (es)
BR (1) BRPI0921148A2 (es)
CA (1) CA2742520A1 (es)
CO (1) CO6382113A2 (es)
CR (1) CR20110256A (es)
CU (1) CU20110108A7 (es)
EA (1) EA201100754A1 (es)
EC (1) ECSP11011053A (es)
IL (1) IL211941A0 (es)
MX (1) MX2011005106A (es)
TW (1) TW201022279A (es)
UY (1) UY32247A (es)
WO (1) WO2010055348A1 (es)
ZA (1) ZA201104395B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2723737A1 (en) * 2011-06-27 2014-04-30 Kyorin Pharmaceutical Co., Ltd. Bridged bicyclic compounds for the treatment of bacterial infections
AR096135A1 (es) * 2013-05-02 2015-12-09 Actelion Pharmaceuticals Ltd Derivados de la quinolona
UY36851A (es) * 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd Compuestos para uso en aplicaciones antibacterianas
US10029995B2 (en) 2015-09-03 2018-07-24 Forma Therapeutics, Inc. [6,6] fused bicyclic HDAC8 inhibitors
JP2019517546A (ja) * 2016-06-08 2019-06-24 アジェンデ・キミケ・リウニテ・アンジェリニ・フランチェスコ・ア・チ・エレ・ア・エフェ・ソシエタ・ペル・アチオニＡｚｉｅｎｄｅ Ｃｈｉｍｉｃｈｅ Ｒｉｕｎｉｔｅ Ａｎｇｅｌｉｎｉ Ｆｒａｎｃｅｓｃｏ Ａ．Ｃ．Ｒ．Ａ．Ｆ．Ｓｏｃｉｅｔａ Ｐｅｒ Ａｚｉｏｎｉ 新しい抗菌性化合物
WO2018225097A1 (en) * 2017-06-08 2018-12-13 Bugworks Research India Pvt Ltd Heterocyclic compounds useful as anti-bacterial agents and method for production thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY150958A (en) * 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
SG164384A1 (en) * 2006-05-26 2010-09-29 Toyama Chemical Co Ltd Novel heterocyclic compound or salt thereof and intermediate thereof
CL2007003693A1 (es) * 2006-12-22 2008-06-27 Actelion Pharmaceuticals Ltd Compuestos derivados de pirido [3,2-b] [1,4] tiazina; composicion farmaceutica que contiene dichos compuestos; y su uso en el tratamiento de infecciones bacterianas.

Also Published As

Publication number Publication date
CR20110256A (es) 2011-07-04
BRPI0921148A2 (pt) 2016-02-23
JP2012508789A (ja) 2012-04-12
ZA201104395B (en) 2012-03-28
AR074340A1 (es) 2011-01-12
KR20110093797A (ko) 2011-08-18
CU20110108A7 (es) 2012-01-31
IL211941A0 (en) 2011-06-30
WO2010055348A1 (en) 2010-05-20
UY32247A (es) 2010-06-30
CA2742520A1 (en) 2010-05-20
AU2009315425A1 (en) 2010-05-20
TW201022279A (en) 2010-06-16
CN102216308A (zh) 2011-10-12
US20110288084A1 (en) 2011-11-24
EP2370444A1 (en) 2011-10-05
CO6382113A2 (es) 2012-02-15
EA201100754A1 (ru) 2012-01-30
MX2011005106A (es) 2011-05-30

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