ECSP11011194A - Composición de liberación pulsátil de sildenafil y proceso - Google Patents

Composición de liberación pulsátil de sildenafil y proceso

Info

Publication number: ECSP11011194A
Authority: EC; Ecuador
Prior art keywords: pulsary; sildenafil; release; composition; sildenafil pulsary
Prior art date: 2008-12-12

Application number

EC2011011194A

Other languages

English (en)

Inventor

Esteban Alejandro Fiore

Original Assignee

Rhein Siegfried Sa De Cv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-12-12

Filing date

2011-07-11

Publication date

2011-09-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42242382&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ECSP11011194(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2011-07-11 Application filed by Rhein Siegfried Sa De Cv filed Critical Rhein Siegfried Sa De Cv

2011-09-30 Publication of ECSP11011194A publication Critical patent/ECSP11011194A/es

Links

BNRNXUUZRGQAQC-UHFFFAOYSA-N sildenafil Chemical compound CCCC1=NN(C)C(C(N2)=O)=C1N=C2C(C(=CC=1)OCC)=CC=1S(=O)(=O)N1CCN(C)CC1 BNRNXUUZRGQAQC-UHFFFAOYSA-N 0.000 title 2
229960003310 sildenafil Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Endocrinology (AREA)
Reproductive Health (AREA)
Heart & Thoracic Surgery (AREA)
Gynecology & Obstetrics (AREA)
Cardiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Medicines Containing Plant Substances (AREA)

EC2011011194A 2008-12-12 2011-07-11 Composición de liberación pulsátil de sildenafil y proceso ECSP11011194A (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/IB2008/003466 WO2010067140A1 (es)	2008-12-12	2008-12-12	Composicion de liberacion pulsatil de sildenafil y proceso para prepararla

Publications (1)

Publication Number	Publication Date
ECSP11011194A true ECSP11011194A (es)	2011-09-30

Family

ID=42242382

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EC2011011194A ECSP11011194A (es)	2008-12-12	2011-07-11	Composición de liberación pulsátil de sildenafil y proceso

Country Status (13)

Country	Link
US (1)	US20110244050A1 (es)
EP (1)	EP2374460A4 (es)
AR (1)	AR071970A1 (es)
BR (1)	BRPI0823356A2 (es)
CL (1)	CL2009002173A1 (es)
CR (1)	CR20110322A (es)
EC (1)	ECSP11011194A (es)
MX (1)	MX339136B (es)
NI (1)	NI201100119A (es)
PA (1)	PA8853801A1 (es)
PE (1)	PE20100471A1 (es)
UY (1)	UY32304A (es)
WO (1)	WO2010067140A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US9498441B2 (en)	2012-01-27	2016-11-22	Siegfried Rhein S.A. De C.V.	Nitazoxadine composition and process to prepare same
EA019381B1 (ru) *	2012-07-20	2014-03-31	Открытое акционерное общество "Химико-фармацевтический комбинат "Акрихин"	Таблетка, содержащая ингибитор фосфодиэстеразы пятого типа, способ ее получения и ее применение
KR101340733B1 (ko) *	2012-12-31	2013-12-12	(주) 에프엔지리서치	신규한 마이크로그래뉼 제형
CA2910865C (en)	2014-07-15	2016-11-29	Isa Odidi	Compositions and methods for reducing overdose
WO2017168174A1 (en) *	2016-04-02	2017-10-05	N4 Pharma Uk Limited	New pharmaceutical forms of sildenafil
WO2018069316A2 (en)	2016-10-10	2018-04-19	Transgene Sa	Immunotherapeutic product and mdsc modulator combination therapy
WO2023037394A1 (en) *	2021-09-13	2023-03-16	Amman Pharmaceutical Industries Company	A pharmaceutical composition of sildenafil and a formulation thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9013750D0 (en)	1990-06-20	1990-08-08	Pfizer Ltd	Therapeutic agents
GB9301192D0 (en) *	1993-06-09	1993-06-09	Trott Francis W	Flower shaped mechanised table
GB9612514D0 (en)	1996-06-14	1996-08-14	Pfizer Ltd	Novel process
HUP0002744A3 (en)	1997-01-06	2001-01-29	Pfizer	Rapidly releasing and taste-masking pharmaceutical dosage form
CA2235642C (en)	1998-05-15	2007-11-13	Torcan Chemical Ltd.	Processes for preparing sildenafil
UA67802C2 (uk) *	1998-10-23	2004-07-15	Пфайзер Рісьоч Енд Дівелепмент Компані, Н.В./С.А.	Фармацевтична композиція з контрольованим вивільненням інгібітора цгмф фде-5 (варіанти), спосіб її одержання та спосіб лікування еректильної дисфункції
US6627223B2 (en) *	2000-02-11	2003-09-30	Eurand Pharmaceuticals Ltd.	Timed pulsatile drug delivery systems
KR20040047747A (ko) *	2001-03-13	2004-06-05	펜웨스트 파머슈티칼즈 컴파니	변시치료 제형
JP2008524332A (ja) *	2004-12-20	2008-07-10	コレジウムファーマシューティカル，インク．	睡眠傷害のための医薬組成物
FR2891459B1 (fr) *	2005-09-30	2007-12-28	Flamel Technologies Sa	Microparticules a liberation modifiee d'au moins un principe actif et forme galenique orale en comprenant
NZ575171A (en) *	2006-08-31	2012-04-27	Aptalis Pharmatech Inc	Drug delivery systems comprising solid solutions of weakly basic drugs

2008
- 2008-12-12 MX MX2011005752A patent/MX339136B/es active IP Right Grant
- 2008-12-12 WO PCT/IB2008/003466 patent/WO2010067140A1/es not_active Ceased
- 2008-12-12 EP EP08878690.0A patent/EP2374460A4/en not_active Withdrawn
- 2008-12-12 US US13/139,261 patent/US20110244050A1/en not_active Abandoned
- 2008-12-12 BR BRPI0823356-0A patent/BRPI0823356A2/pt not_active Application Discontinuation
2009
- 2009-05-29 AR ARP090101956A patent/AR071970A1/es unknown
- 2009-12-07 UY UY0001032304A patent/UY32304A/es not_active Application Discontinuation
- 2009-12-07 PE PE2009001294A patent/PE20100471A1/es not_active Application Discontinuation
- 2009-12-11 PA PA20098853801A patent/PA8853801A1/es unknown
- 2009-12-11 CL CL2009002173A patent/CL2009002173A1/es unknown
2011
- 2011-06-10 NI NI201100119A patent/NI201100119A/es unknown
- 2011-06-10 CR CR20110322A patent/CR20110322A/es unknown
- 2011-07-11 EC EC2011011194A patent/ECSP11011194A/es unknown

Also Published As

Publication number	Publication date
PE20100471A1 (es)	2010-07-22
AR071970A1 (es)	2010-07-28
NI201100119A (es)	2012-08-03
CL2009002173A1 (es)	2010-04-09
EP2374460A1 (en)	2011-10-12
MX2011005752A (es)	2011-08-12
MX339136B (es)	2016-05-13
WO2010067140A1 (es)	2010-06-17
CR20110322A (es)	2011-10-25
US20110244050A1 (en)	2011-10-06
BRPI0823356A2 (pt)	2015-06-16
UY32304A (es)	2010-05-31
PA8853801A1 (es)	2010-07-27
EP2374460A4 (en)	2013-08-21

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BRPI0907884A2 (pt)	2015-07-21	Partícula de liberação
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BRPI0920284A2 (pt)	2016-08-02	composição e método
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BRPI0918372A2 (pt)	2019-09-24	artigo absorvente
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BRPI0821175A2 (pt)	2015-09-15	artigo absorvente
BR112012002247A2 (pt)	2016-06-14	composição e artigo
BRPI0918328B8 (pt)	2018-10-30	composição e artigo
IT1392101B1 (it)	2012-02-09	Composizione comprendente isoflavoni
PL2338519T3 (pl)	2016-06-30	Środek do leczenia zwłóknienia szpiku
BRPI0913807A2 (pt)	2015-10-20	composição e artigo
FI20096058A0 (fi)	2009-10-13	Koostumuksia ja niihin liittyviä menetelmiä ja käyttöjä
EP2242854A4 (en)	2012-08-15	COMPOUNDS AND USES THEREOF
EP2231665A4 (en)	2012-04-25	NEW COMPOSITIONS AND METHODS OF USE