ECSP13012660A - METHOD FOR THE ELABORATION OF NALTREXONE - Google Patents

METHOD FOR THE ELABORATION OF NALTREXONE

Info

Publication number
ECSP13012660A
ECSP13012660A ECSP13012660A ECSP13012660A EC SP13012660 A ECSP13012660 A EC SP13012660A EC SP13012660 A ECSP13012660 A EC SP13012660A EC SP13012660 A ECSP13012660 A EC SP13012660A
Authority
EC
Ecuador
Prior art keywords
naltrexone
elaboration
morphinan
dihydroxy
epoxy
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Faveri Carla De
Florian Anton Martin Huber
Mariano Stivanello
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Publication of ECSP13012660A publication Critical patent/ECSP13012660A/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención hace referencia a un proceso mejorado para la producción de [17-(ciclopropilmetil)-4,5?-epoxi-3,14-dihidroxi-morfinan-6-ona] naltrexona a partir de [4,5- ?-epoxi-3,14-dihidroxi-morfinan-6-ona] noroximorfona mediante alquilación con un ciclopropilmetil haluro.The present invention refers to an improved process for the production of [17- (cyclopropylmethyl) -4,5? -Epoxy-3,14-dihydroxy-morphinan-6-one] naltrexone from [4,5-? - epoxy-3,14-dihydroxy-morphinan-6-one] noroxymorphone by alkylation with a cyclopropylmethyl halide.

ECSP13012660 2010-11-05 2013-06-04 METHOD FOR THE ELABORATION OF NALTREXONE ECSP13012660A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA201001007 2010-11-05

Publications (1)

Publication Number Publication Date
ECSP13012660A true ECSP13012660A (en) 2013-12-31

Family

ID=52669699

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP13012660 ECSP13012660A (en) 2010-11-05 2013-06-04 METHOD FOR THE ELABORATION OF NALTREXONE

Country Status (1)

Country Link
EC (1) ECSP13012660A (en)

Similar Documents

Publication Publication Date Title
IL237061B (en) A continuous process for recovering insoluble oil from an aqueous mixture
MX2015016535A (en) Production method for tagatose.
CY1118742T1 (en) METHOD FOR PREPARING NALTREXON
EP2793251A4 (en) METHOD FOR PRODUCING SEMICONDUCTOR DEVICE
BR112014019909A8 (en) PROCESS FOR THE PRODUCTION OF COMPOUNDS USEFUL AS OREXIN-2 RECEPTOR ANTAGONISTS
EP2845867A4 (en) PROCESS FOR PRODUCING CONJUGATED DIENE RUBBER
IL236523B (en) Method for producing antibody molecules having inter-species, intra-target cross-reactivity
CO7220321A2 (en) Method to produce an additive as well as calcium carbonate from concrete aggregate as well as a device to perform the procedure
MX2016013557A (en) PRODUCTION OF 4-METHYL-TETRAHYDROPIRANS 2-SUBSTITUTED FROM STARTING MATERIALS WITH CONTENT OF 2-RENT-4,4-DIMETHYL-1,3-DI OXANOS.
IN2014DN10417A (en)
EP3088386A4 (en) Method for producing internal olefin sulfonate
ZA201405244B (en) Ignition system for several sets of electronic detonators
IL239689A0 (en) Method for producing antibodies
MX391448B (en) METHOD FOR PRODUCING TETRAHYDROPYRANYL ESTERS.
BR112013027976A2 (en) processes and intermediates in the preparation of morphine analogs by n-demethylation of n-oxides using cyclohydration reagents
MX376491B (en) Method for producing 2-substituted 4-hydroxy-4-methyl-tetrahydropyrans, said method using recycling
EP2990467A4 (en) Method for producing molded solid fuel
BR112012020855A2 (en) METHOD FOR PRODUCING A BIOMOLECULE CONJUGATE
CY1118785T1 (en) PROCEDURE FOR THE RECOVERY OF NALPHEFEN HYDRAULIC
EP2444382A4 (en) Method for producing an organic mineral fertilizer mixture
EP2813501A4 (en) Method for producing 4-benzyl-1-methyl-6-oxabicyclo[3,2,0]heptane derivative
EP3006422A4 (en) Process for producing polyhydric alcohol
ECSP13012660A (en) METHOD FOR THE ELABORATION OF NALTREXONE
CO6700868A2 (en) Method for the elaboration of naltrexone
BR112012029626A2 (en) process for preparing dithianone tetracarboxy dimides