ECSP17025904A - RORC2 PYRROLOPYRIDINE MODULATORS REPLACED WITH METHYL AND TRIFLUOROMETHYL AND METHODS OF USE OF THE SAME - Google Patents

RORC2 PYRROLOPYRIDINE MODULATORS REPLACED WITH METHYL AND TRIFLUOROMETHYL AND METHODS OF USE OF THE SAME

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Publication number
ECSP17025904A
ECSP17025904A ECIEPI201725904A ECPI201725904A ECSP17025904A EC SP17025904 A ECSP17025904 A EC SP17025904A EC IEPI201725904 A ECIEPI201725904 A EC IEPI201725904A EC PI201725904 A ECPI201725904 A EC PI201725904A EC SP17025904 A ECSP17025904 A EC SP17025904A
Authority
EC
Ecuador
Prior art keywords
methods
methyl
trifluoromethyl
rorc2
replaced
Prior art date
Application number
ECIEPI201725904A
Other languages
Spanish (es)
Inventor
Li Xing
Michael L Vazquez
Göran Mattias Wennerstål
Peter Jones
Edouard Zamaratski
Neelu Kaila
Liying Zhang
John David Trzupek
Scot Richard Mente
Andrew Christopher Flick
Mark Edward Schnute
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ECSP17025904A publication Critical patent/ECSP17025904A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención proporciona pirrolopiridinas sustituidas con metilo y trifluorometilo, sus composiciones farmacéuticas, métodos para modular la actividad de RORγ y/o reducir la cantidad de IL-17 en un sujeto, y métodos de tratamiento de diversos trastornos médicos utilizando tales pirrolopiridinas y sus composiciones farmacéuticas.The present invention provides methyl and trifluoromethyl substituted pyrrolopyridines, their pharmaceutical compositions, methods of modulating RORγ activity and / or reducing the amount of IL-17 in a subject, and methods of treating various medical disorders using such pyrrolopyridines and their compositions. pharmaceuticals.

ECIEPI201725904A 2014-09-26 2017-04-26 RORC2 PYRROLOPYRIDINE MODULATORS REPLACED WITH METHYL AND TRIFLUOROMETHYL AND METHODS OF USE OF THE SAME ECSP17025904A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201462055811P 2014-09-26 2014-09-26

Publications (1)

Publication Number Publication Date
ECSP17025904A true ECSP17025904A (en) 2017-09-29

Family

ID=58698667

Family Applications (1)

Application Number Title Priority Date Filing Date
ECIEPI201725904A ECSP17025904A (en) 2014-09-26 2017-04-26 RORC2 PYRROLOPYRIDINE MODULATORS REPLACED WITH METHYL AND TRIFLUOROMETHYL AND METHODS OF USE OF THE SAME

Country Status (2)

Country Link
AR (1) AR101992A1 (en)
EC (1) ECSP17025904A (en)

Also Published As

Publication number Publication date
AR101992A1 (en) 2017-01-25

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