ECSP17058071A - Derivados de tetrahidropiranil benzamida - Google Patents
Derivados de tetrahidropiranil benzamidaInfo
- Publication number
- ECSP17058071A ECSP17058071A ECIEPI201758071A ECPI201758071A ECSP17058071A EC SP17058071 A ECSP17058071 A EC SP17058071A EC IEPI201758071 A ECIEPI201758071 A EC IEPI201758071A EC PI201758071 A ECPI201758071 A EC PI201758071A EC SP17058071 A ECSP17058071 A EC SP17058071A
- Authority
- EC
- Ecuador
- Prior art keywords
- tetrahydropyranil
- benzamide derivatives
- compounds
- benzamide
- derivatives
- Prior art date
Links
- KXDAEFPNCMNJSK-UHFFFAOYSA-N Benzamide Chemical class NC(=O)C1=CC=CC=C1 KXDAEFPNCMNJSK-UHFFFAOYSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4245—Oxadiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyrane Compounds (AREA)
Abstract
La presente invención se refiere a compuestos de la Fórmula siguiente: en donde R, R1-R3 son como se describen en la presente; métodos para tratar pacientes por diabetes usando los compuestos, y procesos para preparar los compuestos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/CN2015/073563 WO2016138631A1 (en) | 2015-03-03 | 2015-03-03 | Imidazo benzamide compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP17058071A true ECSP17058071A (es) | 2017-10-31 |
Family
ID=56849060
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECIEPI201758071A ECSP17058071A (es) | 2015-03-03 | 2017-09-01 | Derivados de tetrahidropiranil benzamida |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US10196385B2 (es) |
| EP (1) | EP3265460A4 (es) |
| JP (1) | JP2018507232A (es) |
| KR (1) | KR20170106483A (es) |
| CN (1) | CN107406436B (es) |
| AU (1) | AU2016228055B2 (es) |
| BR (1) | BR112017015448A2 (es) |
| CA (1) | CA2975413A1 (es) |
| CL (1) | CL2017002148A1 (es) |
| CO (1) | CO2017008721A2 (es) |
| CR (1) | CR20170354A (es) |
| DO (1) | DOP2017000196A (es) |
| EA (1) | EA201791745A1 (es) |
| EC (1) | ECSP17058071A (es) |
| IL (1) | IL253405A0 (es) |
| MA (1) | MA41641A (es) |
| MX (1) | MX2017011087A (es) |
| PE (1) | PE20171650A1 (es) |
| PH (1) | PH12017501560A1 (es) |
| SG (1) | SG11201706718RA (es) |
| SV (1) | SV2017005520A (es) |
| TN (1) | TN2017000372A1 (es) |
| WO (2) | WO2016138631A1 (es) |
| ZA (1) | ZA201704948B (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018014337A1 (en) | 2016-07-22 | 2018-01-25 | Eli Lilly And Company | 3-Chloro-N- [ (1R, 3S) -3- [5- (3, 5-dimethylimidazol-4-yl) -4H-1, 2, 4-triazol-3-yl] cyclohexyl] -N-methyl-benzamide |
| BR112020018286A2 (pt) | 2018-03-09 | 2020-12-29 | Recurium Ip Holdings, Llc | 1,2-di-hidro-3h-pirazolo[3,4-d]pirimidin-3-onas substituídas |
| CN122055357A (zh) * | 2024-09-13 | 2026-05-15 | 成都麻沸散医药科技有限公司 | 一种杂环化合物及其用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008045484A1 (en) | 2006-10-10 | 2008-04-17 | Amgen Inc. | N-aryl pyrazole compounds for use against diabetes |
| US8188098B2 (en) | 2008-05-19 | 2012-05-29 | Hoffmann-La Roche Inc. | GPR119 receptor agonists |
| EP2404896A1 (en) * | 2009-03-05 | 2012-01-11 | Shionogi&Co., Ltd. | Cyclohexane derivative having npy y5 receptor antagonism |
| EP2523558A4 (en) * | 2010-01-15 | 2013-06-19 | Merck Sharp & Dohme | OXADIAZOL BETA CARBOLIN DERIVATIVES AS ANTIDIBLE COMPOUNDS |
| WO2012123449A1 (en) | 2011-03-14 | 2012-09-20 | Boehringer Ingelheim International Gmbh | N- cyclopropyl - n- piperidinylbenzamides as gpr119 modulators |
| WO2015120610A1 (en) | 2014-02-14 | 2015-08-20 | Eli Lilly And Company | Gpr142 agonist compound |
-
2015
- 2015-03-03 WO PCT/CN2015/073563 patent/WO2016138631A1/en not_active Ceased
-
2016
- 2016-02-18 MA MA041641A patent/MA41641A/fr unknown
- 2016-02-19 US US15/118,295 patent/US10196385B2/en active Active
- 2016-02-19 KR KR1020177024303A patent/KR20170106483A/ko not_active Withdrawn
- 2016-02-19 TN TNP/2017/000372A patent/TN2017000372A1/en unknown
- 2016-02-19 CR CR20170354A patent/CR20170354A/es unknown
- 2016-02-19 MX MX2017011087A patent/MX2017011087A/es unknown
- 2016-02-19 SG SG11201706718RA patent/SG11201706718RA/en unknown
- 2016-02-19 JP JP2017546161A patent/JP2018507232A/ja active Pending
- 2016-02-19 BR BR112017015448A patent/BR112017015448A2/pt not_active IP Right Cessation
- 2016-02-19 CN CN201680013049.8A patent/CN107406436B/zh active Active
- 2016-02-19 CA CA2975413A patent/CA2975413A1/en not_active Abandoned
- 2016-02-19 WO PCT/CN2016/074083 patent/WO2016138821A1/en not_active Ceased
- 2016-02-19 AU AU2016228055A patent/AU2016228055B2/en not_active Expired - Fee Related
- 2016-02-19 EA EA201791745A patent/EA201791745A1/ru unknown
- 2016-02-19 PE PE2017001456A patent/PE20171650A1/es not_active Application Discontinuation
- 2016-02-19 EP EP16758437.4A patent/EP3265460A4/en not_active Withdrawn
-
2017
- 2017-07-10 IL IL253405A patent/IL253405A0/en unknown
- 2017-07-20 ZA ZA2017/04948A patent/ZA201704948B/en unknown
- 2017-08-21 DO DO2017000196A patent/DOP2017000196A/es unknown
- 2017-08-22 SV SV2017005520A patent/SV2017005520A/es unknown
- 2017-08-23 CL CL2017002148A patent/CL2017002148A1/es unknown
- 2017-08-28 CO CONC2017/0008721A patent/CO2017008721A2/es unknown
- 2017-08-30 PH PH12017501560A patent/PH12017501560A1/en unknown
- 2017-09-01 EC ECIEPI201758071A patent/ECSP17058071A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20180194755A1 (en) | 2018-07-12 |
| SV2017005520A (es) | 2018-08-27 |
| EP3265460A1 (en) | 2018-01-10 |
| MX2017011087A (es) | 2017-11-10 |
| US10196385B2 (en) | 2019-02-05 |
| DOP2017000196A (es) | 2017-09-15 |
| CR20170354A (es) | 2017-09-05 |
| WO2016138631A1 (en) | 2016-09-09 |
| KR20170106483A (ko) | 2017-09-20 |
| IL253405A0 (en) | 2017-09-28 |
| ZA201704948B (en) | 2019-02-27 |
| AU2016228055A1 (en) | 2017-08-17 |
| EP3265460A4 (en) | 2018-08-08 |
| CO2017008721A2 (es) | 2018-01-05 |
| MA41641A (fr) | 2018-01-09 |
| CN107406436B (zh) | 2021-02-26 |
| TN2017000372A1 (en) | 2019-01-16 |
| CA2975413A1 (en) | 2016-09-09 |
| EA201791745A1 (ru) | 2018-01-31 |
| AU2016228055B2 (en) | 2018-06-07 |
| SG11201706718RA (en) | 2017-09-28 |
| CL2017002148A1 (es) | 2018-04-13 |
| JP2018507232A (ja) | 2018-03-15 |
| CN107406436A (zh) | 2017-11-28 |
| BR112017015448A2 (pt) | 2018-01-30 |
| PH12017501560A1 (en) | 2018-02-05 |
| PE20171650A1 (es) | 2017-11-13 |
| WO2016138821A1 (en) | 2016-09-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ECSP15045801A (es) | Inhibidores de la phd de 6(5hidroxi1hpirazol1il)nicotinamida | |
| ECSP17073191A (es) | Compuestos heterocíclicos como inhibidores de lsd1 | |
| MX2020001757A (es) | Compuestos, sales de los mismos y metodos para el tratamiento de enfermedades. | |
| BR112016023558A2 (pt) | compostos úteis como imunomoduladores | |
| BR112016014020A8 (pt) | moduladores de tetra-hidropiridopirazinas de gpr6. | |
| CU24408B1 (es) | Compuestos de dihidroisoquinolinona sustituida | |
| BR112017017396A2 (pt) | derivados substituídos de nucleosídeos substituídos úteis como agentes anticancerígenos | |
| ECSP15008851A (es) | Compuestos heteroaromáticos como inhibidores de btk | |
| MX2021005052A (es) | Oxiesteroles y métodos de uso de los mismos. | |
| CU24608B1 (es) | Compuestos de dihidrooxadiazinonas sustituidas útiles en el tratamiento de enfermedades hiperproliferativas y métodos para preparar dichos compuestos | |
| UY36737A (es) | 3-amino-1,5,6,7-tetrahidro-4h-indol-4-onas | |
| CO2017000065A2 (es) | Indoles funcionalizados y sustituidos como agentes anti-cáncer | |
| BR112017013286A2 (pt) | composto de isoxazolina, e, uso de um composto de isoxazolina. | |
| GT201400167A (es) | Nuevos derivados de bencil sulfonamida utiles como inhibidores de mogat-2 | |
| DOP2016000211A (es) | Pirazinas moduladoras de gpr6 | |
| BR112016029510A2 (pt) | métodos para a preparação de um composto, e, composto intermediário. | |
| NI201200195A (es) | Procedimiento de preparación de la sal de l - arginina de perindoprilo | |
| CY1124164T1 (el) | Καινοτομος παρασκευη και κρυσταλλωση της ιοσιμενολης | |
| BR112017019850A2 (pt) | ?processo melhorado para a preparação de apremilast? | |
| BR112018070345A2 (pt) | processo para a preparação de derivados de 4-aminoindano e amidas de aminoindano relacionadas | |
| MX382702B (es) | Nuevos compuestos de sulfonilaminobenzamida como antihelminticos. | |
| EA201691999A1 (ru) | Новые сульфониламинобензамидные соединения | |
| BR112016011899A2 (pt) | Processo para preparação de 5-fluoro-1h-pirazóis | |
| DOP2017000196A (es) | Derivados de tetrahidropiranil benzamida | |
| MX2019002607A (es) | Composiciones y metodos para el tratamiento de resistencia a la insulina. |