ECSP21001265A - Compuestos heterocíclicos antihelmínticos - Google Patents

Compuestos heterocíclicos antihelmínticos

Info

Publication number
ECSP21001265A
ECSP21001265A ECSENADI20211265A ECDI202101265A ECSP21001265A EC SP21001265 A ECSP21001265 A EC SP21001265A EC SENADI20211265 A ECSENADI20211265 A EC SENADI20211265A EC DI202101265 A ECDI202101265 A EC DI202101265A EC SP21001265 A ECSP21001265 A EC SP21001265A
Authority
EC
Ecuador
Prior art keywords
antihelmine
heterocyclic
compounds
formula
compound
Prior art date
Application number
ECSENADI20211265A
Other languages
English (en)
Inventor
Alan Long
Hannes Fiepko Koolman
Hyoung Lee
Original Assignee
Boehringer Ingelheim Animal Health Usa Inc
Boehringer Ingelheim Pharma Gmbh Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Animal Health Usa Inc, Boehringer Ingelheim Pharma Gmbh Co Kg filed Critical Boehringer Ingelheim Animal Health Usa Inc
Publication of ECSP21001265A publication Critical patent/ECSP21001265A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Se describen un compuesto de la fórmula (I), (IA) o fórmula (II) o una composición que comprende el compuesto de la fórmula (I), (IA) o fórmula (II) en asociación con un portador veterinariamente aceptable. Se describe un método para controlar helmintos utilizando los mismos.
ECSENADI20211265A 2018-07-09 2021-01-08 Compuestos heterocíclicos antihelmínticos ECSP21001265A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201862695656P 2018-07-09 2018-07-09

Publications (1)

Publication Number Publication Date
ECSP21001265A true ECSP21001265A (es) 2021-02-26

Family

ID=67470666

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSENADI20211265A ECSP21001265A (es) 2018-07-09 2021-01-08 Compuestos heterocíclicos antihelmínticos

Country Status (16)

Country Link
US (2) US12269822B2 (es)
EP (1) EP3820870A1 (es)
JP (1) JP7289349B2 (es)
KR (2) KR20250044476A (es)
CN (1) CN112996788B (es)
AU (1) AU2019301510B2 (es)
CA (1) CA3106092A1 (es)
CL (1) CL2021000031A1 (es)
CO (1) CO2021001375A2 (es)
EC (1) ECSP21001265A (es)
IL (1) IL279977B2 (es)
MX (1) MX2021000293A (es)
PE (1) PE20211275A1 (es)
PH (1) PH12021550024A1 (es)
SG (1) SG11202012922VA (es)
WO (1) WO2020014068A1 (es)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12312356B2 (en) 2020-05-29 2025-05-27 Boehringer Ingelheim Vetmedica Gmbh Anthelmintic heterocyclic compounds
US12503474B2 (en) 2021-11-01 2025-12-23 Boehringer Ingelheim Vetmedica Gmbh Substituted pyrrolo[1,2-b]pyridazines as anthelmintics

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20250044476A (ko) 2018-07-09 2025-03-31 베링거잉겔하임베트메디카게엠베하 구충성 헤테로시클릭 화합물
EP3643711A1 (en) 2018-10-24 2020-04-29 Bayer Animal Health GmbH New anthelmintic compounds
PE20220281A1 (es) 2019-03-19 2022-02-25 Boehringer Ingelheim Animal Health Usa Inc Compuestos de aza-benzotiofeno y aza-benzofurano como antihelminticos
EP3980414A1 (en) 2019-06-07 2022-04-13 Elanco Tiergesundheit AG Bicyclic derivatives for treating endoparasites
AU2021384833A1 (en) 2020-11-18 2023-06-15 Elanco Tiergesundheit Ag N-(2,3-dihydro-1,4-benzoxazin-4-yl)-3-isopropyl-7-(2,3,5-trifluorophenyl)benzo-thiophene-2-carboxamide derivatives and similar compounds for the treatment of heartworm infections
TW202237600A (zh) 2020-12-04 2022-10-01 瑞士商禮藍動物保健股份有限公司 雙環衍生物
WO2024213752A1 (en) 2023-04-14 2024-10-17 Elanco Animal Health Gmbh Long-term prevention and/or treatment of a disease by slo-1 inhibitors
CN121620507A (zh) 2023-08-02 2026-03-06 英特维特国际股份有限公司 具有驱虫活性的甲酰胺-4-喹啉化合物

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