ECSP24038829A - Derivados de naftiridinona para el tratamiento de una enfermedad o un trastorno - Google Patents

Derivados de naftiridinona para el tratamiento de una enfermedad o un trastorno

Info

Publication number
ECSP24038829A
ECSP24038829A ECSENADI202438829A ECDI202438829A ECSP24038829A EC SP24038829 A ECSP24038829 A EC SP24038829A EC SENADI202438829 A ECSENADI202438829 A EC SENADI202438829A EC DI202438829 A ECDI202438829 A EC DI202438829A EC SP24038829 A ECSP24038829 A EC SP24038829A
Authority
EC
Ecuador
Prior art keywords
disorder
disease
treatment
naphthyridinone derivatives
naphthyridinone
Prior art date
Application number
ECSENADI202438829A
Other languages
English (en)
Inventor
Atwood Kim Cheung
Yu Gai
Donglei Liu
Xingjuan Chang
Stefan Peukert
Heng Ge
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of ECSP24038829A publication Critical patent/ECSP24038829A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La invención se refiere a un compuesto de la fórmula (I) o una de sus sales farmacéuticamente aceptables, donde A, R1 y R3 son como se describen en el presente documento, así como composiciones y métodos de uso de dichos compuestos.
ECSENADI202438829A 2021-11-23 2024-05-21 Derivados de naftiridinona para el tratamiento de una enfermedad o un trastorno ECSP24038829A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202163282492P 2021-11-23 2021-11-23
CN2022128601 2022-10-31

Publications (1)

Publication Number Publication Date
ECSP24038829A true ECSP24038829A (es) 2024-06-28

Family

ID=84370237

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSENADI202438829A ECSP24038829A (es) 2021-11-23 2024-05-21 Derivados de naftiridinona para el tratamiento de una enfermedad o un trastorno

Country Status (29)

Country Link
US (2) US12084442B2 (es)
EP (2) EP4656240A1 (es)
JP (1) JP7826477B2 (es)
KR (1) KR20240110040A (es)
CN (1) CN118382623A (es)
AR (1) AR127698A1 (es)
AU (1) AU2022396087A1 (es)
CA (1) CA3235682A1 (es)
CL (1) CL2024001524A1 (es)
CO (1) CO2024006398A2 (es)
CR (1) CR20240216A (es)
DK (1) DK4436662T3 (es)
DO (1) DOP2024000096A (es)
EC (1) ECSP24038829A (es)
ES (1) ES3054973T3 (es)
FI (1) FI4436662T3 (es)
HR (1) HRP20251558T1 (es)
IL (1) IL312689A (es)
JO (1) JOP20240119A1 (es)
LT (1) LT4436662T (es)
MA (1) MA67325B1 (es)
MX (1) MX2024006176A (es)
PE (1) PE20241328A1 (es)
PL (1) PL4436662T3 (es)
PT (1) PT4436662T (es)
RS (1) RS67492B9 (es)
TW (1) TW202329949A (es)
UY (1) UY40025A (es)
WO (1) WO2023094965A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20240391941A1 (en) * 2023-05-24 2024-11-28 Novartis Ag Naphthyridinone derivatives for the treatment of a disease or disorder

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AR050251A1 (es) 2004-05-28 2006-10-11 Speedel Experimenta Ag Compuestos heterociclicos con nitrogeno heteroatomico y composicion farmaceutica en base al compuesto
CA2568165A1 (en) 2004-05-28 2005-12-15 Speedel Experimenta Ag Heterocyclic compounds and their use as aldosterone synthase inhibitors
US20080076784A1 (en) 2004-05-28 2008-03-27 Peter Herold Bicyclic, Nitrogen-Containing Heterocycles and Aromatase Inhibitors
TW200611897A (en) 2004-07-09 2006-04-16 Speedel Experimenta Ag Organic compounds
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WO2022074567A1 (en) 2020-10-06 2022-04-14 Novartis Ag Pharmaceutical compositions comprising naphthyridinone derivatives and their use in the treatment of arrhythmia

Also Published As

Publication number Publication date
PE20241328A1 (es) 2024-06-26
AR127698A1 (es) 2024-02-21
FI4436662T3 (fi) 2025-12-12
US12084442B2 (en) 2024-09-10
RS67492B9 (sr) 2026-02-27
US20250214989A1 (en) 2025-07-03
US20230203032A1 (en) 2023-06-29
DK4436662T3 (da) 2025-12-22
MX2024006176A (es) 2024-06-11
CL2024001524A1 (es) 2024-11-08
WO2023094965A1 (en) 2023-06-01
EP4436662B1 (en) 2025-09-17
PT4436662T (pt) 2025-12-16
CN118382623A (zh) 2024-07-23
JP7826477B2 (ja) 2026-03-09
RS67492B1 (sr) 2025-12-31
PL4436662T3 (pl) 2026-02-16
LT4436662T (lt) 2025-12-29
CA3235682A1 (en) 2023-06-01
EP4656240A1 (en) 2025-12-03
EP4436662A1 (en) 2024-10-02
CR20240216A (es) 2024-07-01
HRP20251558T1 (hr) 2026-01-16
JOP20240119A1 (ar) 2024-05-23
IL312689A (en) 2024-07-01
JP2024543107A (ja) 2024-11-19
AU2022396087A1 (en) 2024-04-11
ES3054973T3 (en) 2026-02-09
MA67325B1 (fr) 2025-11-28
UY40025A (es) 2023-06-15
TW202329949A (zh) 2023-08-01
CO2024006398A2 (es) 2024-07-18
KR20240110040A (ko) 2024-07-12
DOP2024000096A (es) 2024-06-30

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