ECSP951392A - QUINOLIZINONE TYPE COMPOUNDS - Google Patents
QUINOLIZINONE TYPE COMPOUNDSInfo
- Publication number
- ECSP951392A ECSP951392A ECSP951392A ECSP951392A EC SP951392 A ECSP951392 A EC SP951392A EC SP951392 A ECSP951392 A EC SP951392A EC SP951392 A ECSP951392 A EC SP951392A
- Authority
- EC
- Ecuador
- Prior art keywords
- lower alkyl
- formula
- compounds
- hydrogen
- type compounds
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001768 cations Chemical class 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención proporciona compuestos antibacterianos que tienen la formula **formula** y sus sales farmacéuticamente aceptables, esteres y amidas de los mismos, los ejemplos preferidos de los cuales incluyen aquellos compuestos en los que r1 es cicloalquilo de tres a ocho atomos de carbono o fenilo sustituido;r2 se selecciona del grupo que consiste de **formula** r3 es halogeno;r4 es hidrogeno, alquilo inferior, un cation farmacéuticamente aceptable o un grupo del profarmaco; r5 es hidrogeno, alquilo inferior, halo(alquilo inferior) o nr13r14;y, r6 es alquilo inferior, así como también composiciones farmacéuticas que contiene tales compuestos y el uso de los mismos en el tratamiento de las infecciones bacterianas.The present invention provides antibacterial compounds having the formula ** formula ** and their pharmaceutically acceptable salts, esters and amides thereof, preferred examples of which include those compounds in which r1 is cycloalkyl of three to eight carbon atoms or substituted phenyl, r2 is selected from the group consisting of ** formula ** r3 is halogen, r4 is hydrogen, lower alkyl, a pharmaceutically acceptable cation or a group of the prodrug; r5 is hydrogen, lower alkyl, halo (lower alkyl) or nr13r14; and, r6 is lower alkyl, as well as pharmaceutical compositions containing such compounds and their use in the treatment of bacterial infections.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP951392 ECSP951392A (en) | 1995-02-24 | 1995-02-24 | QUINOLIZINONE TYPE COMPOUNDS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP951392 ECSP951392A (en) | 1995-02-24 | 1995-02-24 | QUINOLIZINONE TYPE COMPOUNDS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP951392A true ECSP951392A (en) | 1996-01-15 |
Family
ID=42042037
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP951392 ECSP951392A (en) | 1995-02-24 | 1995-02-24 | QUINOLIZINONE TYPE COMPOUNDS |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP951392A (en) |
-
1995
- 1995-02-24 EC ECSP951392 patent/ECSP951392A/en unknown
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