ECSP961717A -
NEW ARILGLYCINAMIDE DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS
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NEW ARILGLYCINAMIDE DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS
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Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
La presente invención se refiere a nuevos derivados de arilglicinamida de la fórmula general I (gráfico), y sus sales farmacéuticamente aceptables, en que R1 y R2 en común con el N al que están unidos forman un anillo de la fórmula (gráfico), en la que p es 2 o 3, y X es oxígeno, N(CH2)n R6 o Cr7 R8, Y R3, R4, R%, R6, R7, R8, Ar y n, poseen los significados indicados en la memoria descrip¿tiva asi como su prperación y utilización. Los nuevos compuestos son valiosos antagonistas de neuroquininas (taquiquinina).The present invention relates to new arylglycinamide derivatives of the general formula I (graph), and their pharmaceutically acceptable salts, in which R1 and R2 in common with the N to which they are attached form a ring of the formula (graph), in where p is 2 or 3, and X is oxygen, N (CH2) n R6 or Cr7 R8, Y R3, R4, R%, R6, R7, R8, Ar and n, have the meanings indicated in the specification as well as its operation and use. The new compounds are valuable neuroquinine antagonists (tachykinin).
ECSP9617171996-04-121996-04-12
NEW ARILGLYCINAMIDE DERIVATIVES, PROCEDURES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS
ECSP961717A
(en)
DERIVATIVES OF 3- (2-OXO- [1,3¿I¿] BIPIRROLIDINIL-3-ILIDENOMETIL) -CEFEM, A PHARMACEUTICAL COMPOSITION AND THE USE OF THEM FOR THE MANUFACTURE OF A MEDICINAL PRODUCT.
PROCEDURE FOR THE PREPARATION OF THE DERIVATIVES OF THE 8-AZAXANTINA ALQUILAMINOALQUIL OR HETEROCICLILALQUIL SUBSTITUTED IN THE TRIAZOLE RING, AS WELL AS SALTS OF THE SAME ACCEPTABLE IN THERAPEUTICS.