ECSP961891A - D-TARTRADO DE (-) - CIS-6 (S) -FENIL-5 (R) - [4- (2-PIRROLIDIN - 1 ILETOXI), FENIL] - 5,6,7,8- TETRAHIDRONAFTALEN - 2- OL - Google Patents

D-TARTRADO DE (-) - CIS-6 (S) -FENIL-5 (R) - [4- (2-PIRROLIDIN - 1 ILETOXI), FENIL] - 5,6,7,8- TETRAHIDRONAFTALEN - 2- OL

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Publication number
ECSP961891A
ECSP961891A ECSP961891A ECSP961891A EC SP961891 A ECSP961891 A EC SP961891A EC SP961891 A ECSP961891 A EC SP961891A EC SP961891 A ECSP961891 A EC SP961891A
Authority
EC
Ecuador
Prior art keywords
fenil
cis
phenyl
solution
tetrahidronaftalen
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Charles K Chiu
Morgan Meliz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to ECSP961891 priority Critical patent/ECSP961891A/en
Publication of ECSP961891A publication Critical patent/ECSP961891A/en

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Abstract

El invento se refiere a un procedimiento de preparación del compuesto D -tartrato de (-) -cis -6(S) -fenil -5® -[2-pirrolidin - 1 -iletoxi)fenil]-5,6,7,8 - tetrahidronaftalen-2-ol, que comprende: a) disolver cis-6- fenil -5- [4-(2-pirrolidin -1-iletoxi)fenil]- 5,6,7,8-tetrahidronaftalen -2-ol racémico, o enriquecido opticamente de forma parcial, en etanol acuoso en ebullición para formar una disolución; b) añadir a dicha disolución una cantidad molar igual de ácido D-tart rico disuelto en etanol acuoso para formar una segunda disolución; c) enfriar dicha segunda disolución; y d) recoger el producto formado en el paso c.The invention relates to a process for the preparation of compound D-(-) -cis -6 (S) -phenyl -5® - [2-pyrrolidin-1-ethoxy) phenyl] -5,6,7,8 compound - tetrahydronaphthalen-2-ol, comprising: a) dissolving racemic cis-6-phenyl -5- [4- (2-pyrrolidin -1-ylethoxy) phenyl] - 5,6,7,8-tetrahydronaphthalen -2-ol , or optically partially enriched, in boiling aqueous ethanol to form a solution; b) adding to said solution an equal molar amount of rich D-tart acid dissolved in aqueous ethanol to form a second solution; c) cooling said second solution; and d) collecting the product formed in step c.

ECSP961891 1996-10-08 1996-10-08 D-TARTRADO DE (-) - CIS-6 (S) -FENIL-5 (R) - [4- (2-PIRROLIDIN - 1 ILETOXI), FENIL] - 5,6,7,8- TETRAHIDRONAFTALEN - 2- OL ECSP961891A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ECSP961891 ECSP961891A (en) 1996-10-08 1996-10-08 D-TARTRADO DE (-) - CIS-6 (S) -FENIL-5 (R) - [4- (2-PIRROLIDIN - 1 ILETOXI), FENIL] - 5,6,7,8- TETRAHIDRONAFTALEN - 2- OL

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ECSP961891 ECSP961891A (en) 1996-10-08 1996-10-08 D-TARTRADO DE (-) - CIS-6 (S) -FENIL-5 (R) - [4- (2-PIRROLIDIN - 1 ILETOXI), FENIL] - 5,6,7,8- TETRAHIDRONAFTALEN - 2- OL

Publications (1)

Publication Number Publication Date
ECSP961891A true ECSP961891A (en) 1997-12-09

Family

ID=42042617

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP961891 ECSP961891A (en) 1996-10-08 1996-10-08 D-TARTRADO DE (-) - CIS-6 (S) -FENIL-5 (R) - [4- (2-PIRROLIDIN - 1 ILETOXI), FENIL] - 5,6,7,8- TETRAHIDRONAFTALEN - 2- OL

Country Status (1)

Country Link
EC (1) ECSP961891A (en)

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