ECSP972007A - PIPERIDONES - Google Patents

PIPERIDONES

Info

Publication number
ECSP972007A
ECSP972007A ECSP972007A ECSP972007A EC SP972007 A ECSP972007 A EC SP972007A EC SP972007 A ECSP972007 A EC SP972007A EC SP972007 A ECSP972007 A EC SP972007A
Authority
EC
Ecuador
Prior art keywords
compounds
cycloalkyl
preparation
piperidones
cyclopropyl
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Donald Stuart Middleton
Alexander Roderick Mackenzie
Allan Patrick Marchington
Sandra Dora Meadows
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to ECSP972007 priority Critical patent/ECSP972007A/en
Publication of ECSP972007A publication Critical patent/ECSP972007A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La presente invención proporciona compuestos de fórmula (gráfico) y sales de adición de ácido farmacéuticamente aceptables del mismo, en la que X es un enlace directo o alquileno C1 - C4 y R es cicloalquilo C3 - C7, opcionalmente sustituido por 1 ó 2 sustituyentes seleccionados cada uno independientemente entre fluoro y cicloalquilo C3 - C7, a condición de que X no es metileno cuando R es ciclopropilo, junto con procedimientos para la preparación de, intermedios usados en la preparación de, composiciones que contienen y usos de, tales compuestos. Estos compuestos son útiles como antagonistas de taquiquininas.The present invention provides compounds of the formula (graph) and pharmaceutically acceptable acid addition salts thereof, wherein X is a direct bond or C1-C4 alkylene and R is C3-C7 cycloalkyl, optionally substituted by 1 or 2 selected substituents each independently between fluoro and C3-C7 cycloalkyl, provided that X is not methylene when R is cyclopropyl, together with procedures for the preparation of intermediates used in the preparation of, compositions containing, and uses of, such compounds. These compounds are useful as tachykinin antagonists.

ECSP972007 1997-01-22 1997-01-22 PIPERIDONES ECSP972007A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ECSP972007 ECSP972007A (en) 1997-01-22 1997-01-22 PIPERIDONES

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ECSP972007 ECSP972007A (en) 1997-01-22 1997-01-22 PIPERIDONES

Publications (1)

Publication Number Publication Date
ECSP972007A true ECSP972007A (en) 1998-01-09

Family

ID=42042841

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP972007 ECSP972007A (en) 1997-01-22 1997-01-22 PIPERIDONES

Country Status (1)

Country Link
EC (1) ECSP972007A (en)

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