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Priority to ECSP972013priorityCriticalpatent/ECSP972013A/en
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Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Abstract
La invención proporciona compuestos de fórmula I R1 - OP (O) (OH)2 en la que R1 representa la porción no hidroxílica de un compuesto antifúngico de triazol del tipo que comprende un grupo hidroxi terciario; o una sal farmacéuticamente aceptable del mismo. Los compuestos de la invención son útiles en el tratamiento de infecciones fúngicidas y tienen buena solubilidad acuosa.The invention provides compounds of formula I R1-OP (O) (OH) 2 wherein R1 represents the non-hydroxy portion of a triazole antifungal compound of the type comprising a tertiary hydroxy group; or a pharmaceutically acceptable salt thereof. The compounds of the invention are useful in the treatment of fungal infections and have good aqueous solubility.
ECSP9720131997-01-311997-01-31
USEFUL TRIAZOL DERIVATIVES IN THERAPY
ECSP972013A
(en)
A COMPOUND DERIVED FROM TRIAZOL, USE OF THE SAME IN THE MANUFACTURE OF A MEDICINAL PRODUCT FOR THE TREATMENT OR PREVENTION OF FUNGAL INFECTIONS, A PROCEDURE AND A COMPOUND TO PRODUCE IT, A PHARMACEUTICAL FORMULATION CONTAINING IT, AND A SOLUX COMPUTER SOLUBILITY.