ECSP972049A - LACTAMA DERIVATIVES - Google Patents
LACTAMA DERIVATIVESInfo
- Publication number
- ECSP972049A ECSP972049A ECSP972049A ECSP972049A EC SP972049 A ECSP972049 A EC SP972049A EC SP972049 A ECSP972049 A EC SP972049A EC SP972049 A ECSP972049 A EC SP972049A
- Authority
- EC
- Ecuador
- Prior art keywords
- derivatives
- lactama
- antagonists
- present
- agonists
- Prior art date
Links
- QZAYGJVTTNCVMB-UHFFFAOYSA-N serotonin Chemical compound C1=C(O)C=C2C(CCN)=CNC2=C1 QZAYGJVTTNCVMB-UHFFFAOYSA-N 0.000 abstract 4
- 102000035038 5-HT1 receptors Human genes 0.000 abstract 1
- 108091005478 5-HT1 receptors Proteins 0.000 abstract 1
- 102000017911 HTR1A Human genes 0.000 abstract 1
- 101150015707 HTR1A gene Proteins 0.000 abstract 1
- 208000019695 Migraine disease Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 150000003951 lactams Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 206010027599 migraine Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 239000000018 receptor agonist Substances 0.000 abstract 1
- 229940044601 receptor agonist Drugs 0.000 abstract 1
- 239000002464 receptor antagonist Substances 0.000 abstract 1
- 229940044551 receptor antagonist Drugs 0.000 abstract 1
- 229940076279 serotonin Drugs 0.000 abstract 1
- 239000003521 serotonin 5-HT1 receptor agonist Substances 0.000 abstract 1
- 239000002868 serotonin 5-HT1 receptor antagonist Substances 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a derivados de lactama, a procedimientos y a intermedios para su preparación, a composiciones farmacéuticas que los contienen y a su uso en medicina. Los compuestos de la presente invención incluyen agonistas y antagonistas selectivos de receptores de serotonina 1(5-HT 1), específicamente, de uno o de los dos receptores 5-HT1A y 5-HT1). Son útiles en el tratamiento o prevención de la migraña, depresión y otros transtornos para los que están indicados los agonistas o antagonistas de 5-HT1The present invention relates to lactam derivatives, to processes and to intermediates for their preparation, to pharmaceutical compositions containing them and to their use in medicine. The compounds of the present invention include selective serotonin 1 (5-HT 1) receptor agonists and antagonists, specifically, one or both of the 5-HT1A and 5-HT1 receptors). They are useful in the treatment or prevention of migraine, depression and other disorders for which 5-HT1 agonists or antagonists are indicated.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP972049 ECSP972049A (en) | 1997-03-05 | 1997-03-05 | LACTAMA DERIVATIVES |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP972049 ECSP972049A (en) | 1997-03-05 | 1997-03-05 | LACTAMA DERIVATIVES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP972049A true ECSP972049A (en) | 1998-02-13 |
Family
ID=42042882
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP972049 ECSP972049A (en) | 1997-03-05 | 1997-03-05 | LACTAMA DERIVATIVES |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP972049A (en) |
-
1997
- 1997-03-05 EC ECSP972049 patent/ECSP972049A/en unknown
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