ECSP972061A - DERIVATIVES OF 1,25 -DIHIDROXI-16, 22, 23-TRIEN - COLECALCIFEROL - Google Patents
DERIVATIVES OF 1,25 -DIHIDROXI-16, 22, 23-TRIEN - COLECALCIFEROLInfo
- Publication number
- ECSP972061A ECSP972061A ECSP972061A ECSP972061A EC SP972061 A ECSP972061 A EC SP972061A EC SP972061 A ECSP972061 A EC SP972061A EC SP972061 A ECSP972061 A EC SP972061A
- Authority
- EC
- Ecuador
- Prior art keywords
- dihidroxi
- colecalciferol
- trien
- derivatives
- diseases
- Prior art date
Links
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 title 1
- 229960001124 trientine Drugs 0.000 title 1
- 235000005282 vitamin D3 Nutrition 0.000 title 1
- 239000011647 vitamin D3 Substances 0.000 title 1
- 229940021056 vitamin d3 Drugs 0.000 title 1
- 201000010099 disease Diseases 0.000 abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 208000002874 Acne Vulgaris Diseases 0.000 abstract 1
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 206010039793 Seborrhoeic dermatitis Diseases 0.000 abstract 1
- 206010000496 acne Diseases 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 229910052731 fluorine Chemical group 0.000 abstract 1
- 239000011737 fluorine Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 230000003463 hyperproliferative effect Effects 0.000 abstract 1
- 208000032839 leukemia Diseases 0.000 abstract 1
- 230000001613 neoplastic effect Effects 0.000 abstract 1
- 210000001732 sebaceous gland Anatomy 0.000 abstract 1
- 208000008742 seborrheic dermatitis Diseases 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
La invención se refiere a un compuesto de fórmula, (gráfico), en donde R es hidroxilo y R1 es H2 ó CH2, ó R es hidrógeno ó fluor y R1 es CH2. Los compuestos de fórmula I son de utilidad como agentes para el tratamiento de enfermedades hiperproliferativas de la piel, tales como la psoriasis, enfermedades neoplásicas, tales como la leucemia, y enfermedades de las glándulas sebáceas tales como el acné y la dermatitis seborreica.The invention relates to a compound of the formula, (graph), wherein R is hydroxyl and R1 is H2 or CH2, or R is hydrogen or fluorine and R1 is CH2. The compounds of formula I are useful as agents for the treatment of hyperproliferative diseases of the skin, such as psoriasis, neoplastic diseases, such as leukemia, and diseases of the sebaceous glands such as acne and seborrheic dermatitis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP972061 ECSP972061A (en) | 1997-03-20 | 1997-03-20 | DERIVATIVES OF 1,25 -DIHIDROXI-16, 22, 23-TRIEN - COLECALCIFEROL |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP972061 ECSP972061A (en) | 1997-03-20 | 1997-03-20 | DERIVATIVES OF 1,25 -DIHIDROXI-16, 22, 23-TRIEN - COLECALCIFEROL |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP972061A true ECSP972061A (en) | 1998-02-13 |
Family
ID=42042894
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP972061 ECSP972061A (en) | 1997-03-20 | 1997-03-20 | DERIVATIVES OF 1,25 -DIHIDROXI-16, 22, 23-TRIEN - COLECALCIFEROL |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP972061A (en) |
-
1997
- 1997-03-20 EC ECSP972061 patent/ECSP972061A/en unknown
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