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Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Nitrogen Condensed Heterocyclic Rings
(AREA)
Abstract
La presente invención se refiere a agentes anti-bacteriales de carbapenem en los cuales el núcleo de carbapenem esta sustituído en la posición 2 con un naflosultam unido a un grupo CH2. El naflosultam está adicionalmente sustituido con varios grupos sustituyentes incluyendo al menos a un grupo catiónico. Los compuestos están representados por la fórmula I: (gráfico), también se incluye composiciones farmacéuticas y métodos de uso.The present invention relates to carbapenem antibacterial agents in which the carbapenem nucleus is substituted at the 2-position with a naflosultam attached to a CH2 group. Naflosultam is further substituted by various substituent groups including at least one cationic group. Compounds are represented by formula I: (graph), pharmaceutical compositions and methods of use are also included.
ECSP9720911997-04-231997-04-23
ANTI-BACTERIAL COMPOUNDS OF CARBAPENEM, COMPOSITIONS CONTAINING THEM AND TREATMENT METHODS
ECSP972091A
(en)
New 7- (substituted) -8- (substituted) -9- (substituted amino) -6-demethyl-6-deoxy-tetracyclines, pharmaceutical compositions containing them and intermediates in their preparation
COMPOUND 2-IMIDAZOLINILAMINOINDOL, PHARMACEUTICAL COMPOSITION THAT INCLUDES SUCH COMPOUND AND USE OF THE SAME FOR THE MANUFACTURE OF A MEDICINAL PRODUCT.