ECSP972098A - COMPLEXES OF INCLUSION OF SALTS OF ARY METEROCICLICOS - Google Patents
COMPLEXES OF INCLUSION OF SALTS OF ARY METEROCICLICOSInfo
- Publication number
- ECSP972098A ECSP972098A ECSP972098A ECSP972098A EC SP972098 A ECSP972098 A EC SP972098A EC SP972098 A ECSP972098 A EC SP972098A EC SP972098 A ECSP972098 A EC SP972098A
- Authority
- EC
- Ecuador
- Prior art keywords
- ziprasidone
- salts
- inclusion
- meterociclicos
- ary
- Prior art date
Links
- 229920000858 Cyclodextrin Polymers 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- MVWVFYHBGMAFLY-UHFFFAOYSA-N ziprasidone Chemical compound C1=CC=C2C(N3CCN(CC3)CCC3=CC=4CC(=O)NC=4C=C3Cl)=NSC2=C1 MVWVFYHBGMAFLY-UHFFFAOYSA-N 0.000 abstract 3
- -1 bensylate Chemical compound 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- HFHDHCJBZVLPGP-UHFFFAOYSA-N schardinger α-dextrin Chemical compound O1C(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC(C(O)C2O)C(CO)OC2OC(C(C2O)O)C(CO)OC2OC2C(O)C(O)C1OC2CO HFHDHCJBZVLPGP-UHFFFAOYSA-N 0.000 abstract 2
- 229960000607 ziprasidone Drugs 0.000 abstract 2
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 abstract 1
- AFVFQIVMOAPDHO-UHFFFAOYSA-N Methanesulfonic acid Chemical compound CS(O)(=O)=O AFVFQIVMOAPDHO-UHFFFAOYSA-N 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- CCIVGXIOQKPBKL-UHFFFAOYSA-M ethanesulfonate Chemical compound CCS([O-])(=O)=O CCIVGXIOQKPBKL-UHFFFAOYSA-M 0.000 abstract 1
- VNDHXHMRJVTMTK-WZVRVNPQSA-H hexasodium 4-[[(1S,3R,5R,6S,8R,10R,11S,13R,15R,16S,18R,20R,21S,23R,25R,26S,28R,30R,31S,33R,35R,36R,37R,38R,39R,40R,41R,42R,43R,44R,45R,46R,47R,48R,49R)-36,37,38,39,40,41,42,43,44,45,46,47,48,49-tetradecahydroxy-10-(hydroxymethyl)-15,20,25,30,35-pentakis(4-sulfonatobutoxymethyl)-2,4,7,9,12,14,17,19,22,24,27,29,32,34-tetradecaoxaoctacyclo[31.2.2.23,6.28,11.213,16.218,21.223,26.228,31]nonatetracontan-5-yl]methoxy]butane-1-sulfonate Chemical compound [Na+].[Na+].[Na+].[Na+].[Na+].[Na+].OC[C@H]1O[C@@H]2O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3COCCCCS([O-])(=O)=O)O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3COCCCCS([O-])(=O)=O)O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3COCCCCS([O-])(=O)=O)O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3COCCCCS([O-])(=O)=O)O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3COCCCCS([O-])(=O)=O)O[C@H]3[C@H](O)[C@@H](O)[C@H](O[C@@H]3COCCCCS([O-])(=O)=O)O[C@H]1[C@H](O)[C@H]2O VNDHXHMRJVTMTK-WZVRVNPQSA-H 0.000 abstract 1
- 229950006327 napsilate Drugs 0.000 abstract 1
- 229940095064 tartrate Drugs 0.000 abstract 1
- JOXIMZWYDAKGHI-UHFFFAOYSA-N toluene-4-sulfonic acid Chemical compound CC1=CC=C(S(O)(=O)=O)C=C1 JOXIMZWYDAKGHI-UHFFFAOYSA-N 0.000 abstract 1
- ODLHGICHYURWBS-LKONHMLTSA-N trappsol cyclo Chemical compound CC(O)COC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](COCC(C)O)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)COCC(O)C)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1COCC(C)O ODLHGICHYURWBS-LKONHMLTSA-N 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Composiciones de materia que contienen una sal farmacéuticamente aceptable de un compuesto aril-heterocíclico, tal como la ziprasidona en una ciclodextrina. Las iclodextrinas preferidas son la SBECD y la HPBCD. La composición puede contener una mezcla seca, un complejo de inclusión seco o una solución acuosa. El complejo de inclusión sal/ciclodextrina proporciona preferentemente una cantidad de ziprasidona de al menos 2,5 mgA/ml cuando el complejo se disuelve en agua 40% p/v. Se prefieren varias sales de ziprasidona, incluyendo el mesilato, esilato, bensilato, tartrato, napsilato y tosilato.Compositions of matter containing a pharmaceutically acceptable salt of an aryl-heterocyclic compound, such as ziprasidone in a cyclodextrin. The preferred iclodextrins are SBECD and HPBCD. The composition may contain a dry mixture, a dry inclusion complex, or an aqueous solution. The salt / cyclodextrin inclusion complex preferably provides an amount of ziprasidone of at least 2.5 mgA / ml when the complex is dissolved in 40% w / v water. Various ziprasidone salts are preferred, including mesylate, esylate, bensylate, tartrate, napsilate, and tosylate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP972098 ECSP972098A (en) | 1997-04-28 | 1997-04-28 | COMPLEXES OF INCLUSION OF SALTS OF ARY METEROCICLICOS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP972098 ECSP972098A (en) | 1997-04-28 | 1997-04-28 | COMPLEXES OF INCLUSION OF SALTS OF ARY METEROCICLICOS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP972098A true ECSP972098A (en) | 1998-04-07 |
Family
ID=42042929
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP972098 ECSP972098A (en) | 1997-04-28 | 1997-04-28 | COMPLEXES OF INCLUSION OF SALTS OF ARY METEROCICLICOS |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP972098A (en) |
-
1997
- 1997-04-28 EC ECSP972098 patent/ECSP972098A/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CO4600677A1 (en) | ARIL-HETERO-CYCLIC SALT INCLUSION COMPLEXES | |
| RU94028890A (en) | COMPOSITIONS OF DERIVATIVES OF CYCLODEXTRIN, COMPOSITIONS, CONTAINING MEDICINES AND DERIVATIVES OF CYCLODEXTRINS | |
| FR2789079B3 (en) | PYRAZOLECARBOXYLIC ACID DERIVATIVE, ITS PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | |
| BR0215331A (en) | Aqueous compositions containing metronidazole | |
| AR035482A1 (en) | USE OF A CYANOQUINOLINE COMPOUND FOR THE MANUFACTURE OF A MEDICINAL PRODUCT TO TREAT OR INHIBIT COLONY POLYPS | |
| CO5271657A1 (en) | DERIVATIVES OF AZAINDOL | |
| SV2002000356A (en) | NEW DERIVATIVES OF PIPERAZINA REF. PC10770AIXN / BB | |
| ES2190075T3 (en) | SOLID PHARMACEUTICAL FORMULATIONS CONTAINING A PHYSICAL MIXTURE OF SULFOALQUIL-ETER-CYCLODEXTRINE AND A THERAPEUTIC AGENT. | |
| NL350024I2 (en) | Combinations of fungicidal active substances. | |
| MY121397A (en) | Ziprasidone formulations | |
| PE84899A1 (en) | PHARMACEUTICAL FORMULATIONS CONTAINING VORICONAZOLE | |
| AR030933A1 (en) | TRIAZOL DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | |
| ES2008865B3 (en) | PROCEDURE FOR PREPARING AN ANTISEPTIC COMPOSITION. | |
| TR200301723T4 (en) | 1,3 Dihydro-2H-indol-2 one derivatives and their use as binding agents for V1B or V1B receptors of arginine-vasopressin | |
| AU6593301A (en) | Compounds with a sulphonamide group and pharmaceutical compositions containing these compounds | |
| SE0102843L (en) | Stabilized oral pharmaceutical composition containing iodide and iodate and method | |
| BR9805875A (en) | Pharmaceutical compositions of droloxifene. | |
| TR200000414T2 (en) | 2- (4-Aryl or heteroaryl-piperazin-1-ylmethyl) -1H-indole derivatives. | |
| DK1104289T3 (en) | New oral formulations for 5-HT 4 agonists or antagonists | |
| GT199800196A (en) | COMBINATIONS OF STATIN-CARBOXYALKYL ETHER. | |
| DE69928646D1 (en) | DERIVATIVES OF THE STREPTOGRAMIN, THEIR PREPARATION AND PREPARATIONS CONTAINING THEM | |
| GB9621437D0 (en) | Improvements in or relating to organic compositions | |
| MX9709451A (en) | Benzisoxazole and indazole derivatives as antipsychotic agents. | |
| ATE474550T1 (en) | USE OF BETA-CYCLODEXTRIN WITH SURFACTANTS AS PEARLY SHIMMER AGENT | |
| ATE221542T1 (en) | WATER SOLUBLE GLYCOLIZED DERIVATIVES OF 1,2-DITHIINE COMPOUNDS |