ECSP972134A - ARIL PIRIMIDINE DERIVATIVES (CASE RAN 408/100 - Google Patents
ARIL PIRIMIDINE DERIVATIVES (CASE RAN 408/100Info
- Publication number
- ECSP972134A ECSP972134A ECSP972134A ECSP972134A EC SP972134 A ECSP972134 A EC SP972134A EC SP972134 A ECSP972134 A EC SP972134A EC SP972134 A ECSP972134 A EC SP972134A
- Authority
- EC
- Ecuador
- Prior art keywords
- aril
- treatment
- relates
- pirimidine derivatives
- derivatives
- Prior art date
Links
- 102000006969 5-HT2B Serotonin Receptor Human genes 0.000 abstract 1
- 108010072584 5-HT2B Serotonin Receptor Proteins 0.000 abstract 1
- 208000019695 Migraine disease Diseases 0.000 abstract 1
- 150000001204 N-oxides Chemical class 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000009472 formulation Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 206010027599 migraine Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 abstract 1
- 150000003230 pyrimidines Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a derivados de pirimidina y a sales o N-óxidos derivados farmacéuticamente aceptables, que muestran propiedades farmacológicas útiles, de uso particular como antagonistas selectivos del receptor 5HT2B, a su preparación a composiciones farmacéuticas conteniéndolos y a su uso en el tratamiento de diversas enfermedades, especialmente de la migraña. La invención se refiere asi mismo a formulaciones y métodos a tratamiento.The present invention relates to pyrimidine derivatives and pharmaceutically acceptable salts or N-oxides derived, which show useful pharmacological properties, of particular use as selective antagonists of the 5HT2B receptor, to their preparation to pharmaceutical compositions containing them and to their use in the treatment of various diseases, especially migraine. The invention also relates to formulations and methods of treatment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP972134 ECSP972134A (en) | 1997-05-22 | 1997-05-22 | ARIL PIRIMIDINE DERIVATIVES (CASE RAN 408/100 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP972134 ECSP972134A (en) | 1997-05-22 | 1997-05-22 | ARIL PIRIMIDINE DERIVATIVES (CASE RAN 408/100 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP972134A true ECSP972134A (en) | 1998-07-23 |
Family
ID=42042965
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP972134 ECSP972134A (en) | 1997-05-22 | 1997-05-22 | ARIL PIRIMIDINE DERIVATIVES (CASE RAN 408/100 |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP972134A (en) |
-
1997
- 1997-05-22 EC ECSP972134 patent/ECSP972134A/en unknown
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