ECSP972298A - NICOTINIC AGENTS IN THERAPY - Google Patents
NICOTINIC AGENTS IN THERAPYInfo
- Publication number
- ECSP972298A ECSP972298A ECSP972298A ECSP972298A EC SP972298 A ECSP972298 A EC SP972298A EC SP972298 A ECSP972298 A EC SP972298A EC SP972298 A ECSP972298 A EC SP972298A
- Authority
- EC
- Ecuador
- Prior art keywords
- neurological
- procedures
- formula
- compounds
- mental disorders
- Prior art date
Links
- 239000000181 nicotinic agonist Substances 0.000 title 1
- 238000002560 therapeutic procedure Methods 0.000 title 1
- 208000012902 Nervous system disease Diseases 0.000 abstract 2
- 208000025966 Neurological disease Diseases 0.000 abstract 2
- 230000006949 cholinergic function Effects 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000003247 decreasing effect Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 230000000926 neurological effect Effects 0.000 abstract 2
- 208000020016 psychiatric disease Diseases 0.000 abstract 2
- SNICXCGAKADSCV-JTQLQIEISA-N (-)-Nicotine Chemical compound CN1CCC[C@H]1C1=CC=CN=C1 SNICXCGAKADSCV-JTQLQIEISA-N 0.000 abstract 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 208000006096 Attention Deficit Disorder with Hyperactivity Diseases 0.000 abstract 1
- 206010009900 Colitis ulcerative Diseases 0.000 abstract 1
- 201000004311 Gilles de la Tourette syndrome Diseases 0.000 abstract 1
- 208000023105 Huntington disease Diseases 0.000 abstract 1
- 206010020651 Hyperkinesia Diseases 0.000 abstract 1
- 208000000269 Hyperkinesis Diseases 0.000 abstract 1
- 206010026749 Mania Diseases 0.000 abstract 1
- 208000005314 Multi-Infarct Dementia Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 206010039966 Senile dementia Diseases 0.000 abstract 1
- 206010043118 Tardive Dyskinesia Diseases 0.000 abstract 1
- 208000000323 Tourette Syndrome Diseases 0.000 abstract 1
- 208000016620 Tourette disease Diseases 0.000 abstract 1
- 201000006704 Ulcerative Colitis Diseases 0.000 abstract 1
- 201000004810 Vascular dementia Diseases 0.000 abstract 1
- 230000007000 age related cognitive decline Effects 0.000 abstract 1
- 230000036592 analgesia Effects 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 230000006735 deficit Effects 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 206010013932 dyslexia Diseases 0.000 abstract 1
- 206010015037 epilepsy Diseases 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229960002715 nicotine Drugs 0.000 abstract 1
- SNICXCGAKADSCV-UHFFFAOYSA-N nicotine Natural products CN1CCCC1C1=CC=CN=C1 SNICXCGAKADSCV-UHFFFAOYSA-N 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 201000000980 schizophrenia Diseases 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Compuestos azabicíclicos condensados con piridona de la fórmula (gráfico)y sus sales y profármacos farmacéuticamente aceptables, en los que R1,R2 y R3 son como se definen mas adelante, los intermedios y los procedimientos para su preparación, las composiciones y procedimientos para usar los compuestos de fórmula I en el que el tratamiento y trastornos neurológicos y mentales relacionados con una disminución de la función colinérgica, tales como adición a nicotina, Corea de Huntington, discinesia tardia, hipercinesia, manía, dislexia, esquizofrenia, analgesia, trastornos de déficit de atención (ADD), demencia multi-infarto, descenso cognitivo relacionado con la edad, epilepsia, trastornos neurológicos y mentales relacionados con una disminución de la función colinégica, demencia senil de tipo Alzheimer; enfermedad de Parkinson, transtorno de hiperactividad de déficit de atención (ADHD), ansiedad, obesidad, Síndrome de Tourette y colitis ulcerativa.Pyridone-condensed azabicyclic compounds of the formula (graph) and their pharmaceutically acceptable salts and prodrugs, wherein R1, R2 and R3 are as defined below, the intermediates and procedures for their preparation, the compositions and procedures for using the compounds of formula I in which treatment and neurological and mental disorders related to decreased cholinergic function, such as nicotine addition, Huntington's chorea, tardive dyskinesia, hyperkinesia, mania, dyslexia, schizophrenia, analgesia, deficit disorders attention (ADD), multi-infarct dementia, age-related cognitive decline, epilepsy, neurological and mental disorders related to decreased cholinergic function, senile dementia of the Alzheimer type; Parkinson's disease, attention deficit hyperactivity disorder (ADHD), anxiety, obesity, Tourette syndrome and ulcerative colitis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP972298 ECSP972298A (en) | 1997-10-30 | 1997-10-30 | NICOTINIC AGENTS IN THERAPY |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP972298 ECSP972298A (en) | 1997-10-30 | 1997-10-30 | NICOTINIC AGENTS IN THERAPY |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP972298A true ECSP972298A (en) | 1998-11-23 |
Family
ID=42043127
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP972298 ECSP972298A (en) | 1997-10-30 | 1997-10-30 | NICOTINIC AGENTS IN THERAPY |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP972298A (en) |
-
1997
- 1997-10-30 EC ECSP972298 patent/ECSP972298A/en unknown
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