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Priority to ECSP972320priorityCriticalpatent/ECSP972320A/en
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Medicines That Contain Protein Lipid Enzymes And Other Medicines
(AREA)
Abstract
Se describen compuestos que inhiben la liberación de péptidos B-amiloides y/o sus sintesis, y por consiguiente que tienen utilidad para tratar la enfermedad de Alzheimer. Asi mismo se describen composiciones farmacéuticas que comprenden un compuesto que inhibe la liberación de péptidos B-amiloides y/o su sintesis asi como también métodos para tratar la enfermedad de Alzheimer tanto profiláctica como terapéuticamente con dichas composiciones farmacéuticas.Compounds are described that inhibit the release of B-amyloid peptides and / or their syntheses, and therefore have utility in treating Alzheimer's disease. Also disclosed are pharmaceutical compositions comprising a compound that inhibits the release of B-amyloid peptides and / or their synthesis as well as methods of treating Alzheimer's disease both prophylactically and therapeutically with such pharmaceutical compositions.
ECSP9723201997-11-211997-11-21
METHODS AND COMPOSITIONS FOR INHIBITING THE RELEASE OF β-AMYLOID PEPTIDE AND / OR ITS SYNTHESIS
ECSP972320A
(en)
ACID N- (ARIL AND OR HETEROARILASETHL) AMINO ESTER, COMPOSITION OF THE PHARMACY CONTAINING IT, AND THE METHODS TO SPRIT THE BETHA-AMILOID PEPTIDES AND OR SYNTHESIAN COMPOSITION CONTAINING IT, AND THE METHODS TO SPRIT THE BETHA-AMILOID PEPTIDES AND OR SYNTHESIAN COMPOSITION THAT CONTAINS IT, AND THE METHODS TO SPRIT THE RELEASE OF BETHA-AMILOID PEPTIDES AND OR THE SYNTHESIA USING THE COMPOUND.
Compound, pharmaceutical composition, methods for inhibiting the release of beta-amyloid peptide and / or its synthesis, for treating Alzheimer's disease, and for preventing the disease and the progress of Alzheimer's disease, and, use of a compound.
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising them and processes to inhibit beta-amyloid peptide release and / or its synthesis by using such compounds
Derivatives of n- (aryl / heteroaryl) amino acid, pharmaceutical compositions comprising them, and methods for inhibiting the release of beta-amyloid peptide and / or its synthesis by using such compounds
Compound, pharmaceutical composition, methods for inhibiting the release of beta-amyloid peptide and / or its synthesis, for treating alzheimer's disease, for preventing alzheimer's disease, and for inhibiting the progress of alzheimer's disease, processes for preparing the compound , and to prepare lactams, and, use of compound
BACKGROUND OF THE INVENTION The present invention relates to a pharmaceutical composition comprising a pharmaceutically acceptable carrier and a pharmaceutically acceptable excipient.
HETEROCICLIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS THAT UNDERSTAND THEM AND METHODS TO INHIBIT THE RELEASE OF PEPTIDE B - AMYLOID AND / OR ITS SYNTHESIS THROUGH THE USE OF SUCH COMPOUNDS
CYCLLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS UNDERSTANDING THEM, AND METHODS TO INHIBIT THE RELEASE OF THE β-AMYLOID PEPTIDE AND / OR ITS SYNTHESIS THROUGH THE USE OF SUCH COMPOUNDS
CRYSTAL FORM OF THE 1S- [1 ALPHA (2S *, 3R *), 9 ALPHA -] - 6,10-DIOXO-N- (2-ETOXI-5-OXO-TETRAHIDRO-3-FURANIL) -9 - [[ (1-ISOQUINOLIL) CARBONIL] AMINO] OCTAHIDRO-6-H-PIRIDAZINO [1,2-A] [1,2] DIAZEPINA-1-CARBOXAMIDE, ITS PREPARATION PROCEDURE, ITS APPLICATION IN THE PREPARATION OF A MEDICINAL PRODUCT, AND COMPOSITION