ECSP982443A - COMPOSITIONS AND METHODS TO REDUCE EYE HYPERTENSION - Google Patents
COMPOSITIONS AND METHODS TO REDUCE EYE HYPERTENSIONInfo
- Publication number
- ECSP982443A ECSP982443A ECSP982443A ECSP982443A EC SP982443 A ECSP982443 A EC SP982443A EC SP982443 A ECSP982443 A EC SP982443A EC SP982443 A ECSP982443 A EC SP982443A
- Authority
- EC
- Ecuador
- Prior art keywords
- compositions
- methods
- prostaglandin
- intraocular pressure
- reduce eye
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 3
- 206010020772 Hypertension Diseases 0.000 title 1
- 150000003180 prostaglandins Chemical class 0.000 abstract 3
- 239000013543 active substance Substances 0.000 abstract 2
- 230000004410 intraocular pressure Effects 0.000 abstract 2
- 239000003755 preservative agent Substances 0.000 abstract 2
- 208000010412 Glaucoma Diseases 0.000 abstract 1
- 239000000654 additive Substances 0.000 abstract 1
- 230000000996 additive effect Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- XXUPXHKCPIKWLR-JHUOEJJVSA-N isopropyl unoprostone Chemical compound CCCCCCCC(=O)CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(=O)OC(C)C XXUPXHKCPIKWLR-JHUOEJJVSA-N 0.000 abstract 1
- 239000002207 metabolite Substances 0.000 abstract 1
- 239000002736 nonionic surfactant Substances 0.000 abstract 1
- 230000002335 preservative effect Effects 0.000 abstract 1
- 229950008081 unoprostone isopropyl Drugs 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Una composición oftálmica mejorada, que incluye agentes activos de prostaglandina, la cual es especialmente útil para bajar la presión intraocular asociada con glaucoma. Se logran mejoras en la eficacia de reducción de la presión intraocular, en la eficacia del conservador, y concentraciones de aditivo reducidas, mediante la utilización de las composiciones dadas a conocer, las cuales incluyen un agente activo de prostaglandina (por ejemplo, isopropil-unoprostona, un metabolito de una prostaglandina de la serie F), en conjunto con tensoactivos no iónicos seleccionados, conservadores y agentes de ajuste de tonicidad no iónicos.An improved ophthalmic composition, including prostaglandin active agents, which is especially useful in lowering the intraocular pressure associated with glaucoma. Improvements in intraocular pressure reduction efficacy, preservative efficacy, and reduced additive concentrations are achieved through the use of the disclosed compositions, which include a prostaglandin active agent (eg, isopropyl-unoprostone , a metabolite of a prostaglandin series F), in conjunction with selected nonionic surfactants, preservatives, and nonionic tonicity adjusting agents.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP982443 ECSP982443A (en) | 1998-03-12 | 1998-03-12 | COMPOSITIONS AND METHODS TO REDUCE EYE HYPERTENSION |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP982443 ECSP982443A (en) | 1998-03-12 | 1998-03-12 | COMPOSITIONS AND METHODS TO REDUCE EYE HYPERTENSION |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP982443A true ECSP982443A (en) | 1999-01-05 |
Family
ID=42043365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP982443 ECSP982443A (en) | 1998-03-12 | 1998-03-12 | COMPOSITIONS AND METHODS TO REDUCE EYE HYPERTENSION |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP982443A (en) |
-
1998
- 1998-03-12 EC ECSP982443 patent/ECSP982443A/en unknown
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