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Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Cephalosporin Compounds
(AREA)
Abstract
Acidos 7-(((5-amino-1, 2, 4 -tiadiazol -3- il) - (Z) - (fluorometoxiimino) acetil)amino)-3-imino (insustituido o sustituido)-1-piperazinilmetil -hidrazono(sustituido)) metil -3-cefem-4-carboxílicos y ésteres de ácido carboxílico, en donde los sustituyentes se seleccionan a partir de alquilo, cicloalquilo, aralquilo, arilo, alquenilo o alqunilo; por ejemplo en forma libre o en la forma de una sal y/o en la forma de un solvato; un proceso para su producción, y su uso como un producto farmacéutico, por ejemplo como un antibiótico.Acids 7 - (((5-amino-1, 2, 4-thiadiazol -3-yl) - (Z) - (fluoromethoxyimino) acetyl) amino) -3-imino (unsubstituted or substituted) -1-piperazinylmethyl-hydrazone ( substituted)) methyl -3-cephem-4-carboxylic and carboxylic acid esters, wherein the substituents are selected from alkyl, cycloalkyl, aralkyl, aryl, alkenyl or alkynyl; for example in free form or in the form of a salt and / or in the form of a solvate; a process for its production, and its use as a pharmaceutical product, for example as an antibiotic.
CRYSTALLINE FORM OF ANHYDRAUS SALT COMPOSED OF ACIDS 7 - ((1A, 5A, 6A) -6-AMINO-3-AZABICICLO (3.1.0.) HEX-3-IL) -6-FLUORO-1- (2, 4-DIFLUOROFENIL) -1,4-DIHIDRO-4-OXO-1,8-NAFTIRIDINA-3-CARBOXILICO AND METANOSULFONICO.
6-(1-hydroxyethyl)-2-(2-aminoethylthio)-1,1-disubstituted-1-carbadethiapen-2-em-3-carboxylic acids, a process for preparing the same, an antibiotic pharmaceutical composition comprising the same, intermediates useful in a synthesis of that kind and processes for preparing intermediates suitable for the synthesis of that kind