ECSP982489A - ACTIVATED PROTEIN C FORMULATIONS - Google Patents
ACTIVATED PROTEIN C FORMULATIONSInfo
- Publication number
- ECSP982489A ECSP982489A ECSP982489A ECSP982489A EC SP982489 A ECSP982489 A EC SP982489A EC SP982489 A ECSP982489 A EC SP982489A EC SP982489 A ECSP982489 A EC SP982489A
- Authority
- EC
- Ecuador
- Prior art keywords
- activated protein
- formulations
- raffin
- mannite
- trehalose
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 abstract 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 abstract 1
- 101800004937 Protein C Proteins 0.000 abstract 1
- 102100036546 Salivary acidic proline-rich phosphoprotein 1/2 Human genes 0.000 abstract 1
- 101800001700 Saposin-D Proteins 0.000 abstract 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 abstract 1
- 229930006000 Sucrose Natural products 0.000 abstract 1
- HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 abstract 1
- HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 abstract 1
- 239000004067 bulking agent Substances 0.000 abstract 1
- 239000012931 lyophilized formulation Substances 0.000 abstract 1
- 235000010355 mannitol Nutrition 0.000 abstract 1
- 229960000856 protein c Drugs 0.000 abstract 1
- 239000005720 sucrose Substances 0.000 abstract 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
El invento se refiere a una formulación liofilizada estable que comprende proteína C activada y un agente voluminizante seleccionado del grupo consistente de manito, trealosa, rafinoa y sacarosa y mezclas similares de los mismos.The invention relates to a stable lyophilized formulation comprising activated protein C and a bulking agent selected from the group consisting of mannite, trehalose, raffin and sucrose and the like mixtures thereof.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP982489 ECSP982489A (en) | 1998-04-27 | 1998-04-27 | ACTIVATED PROTEIN C FORMULATIONS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP982489 ECSP982489A (en) | 1998-04-27 | 1998-04-27 | ACTIVATED PROTEIN C FORMULATIONS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP982489A true ECSP982489A (en) | 1999-04-13 |
Family
ID=42043410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP982489 ECSP982489A (en) | 1998-04-27 | 1998-04-27 | ACTIVATED PROTEIN C FORMULATIONS |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP982489A (en) |
-
1998
- 1998-04-27 EC ECSP982489 patent/ECSP982489A/en unknown
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