ECSP982518A - DERIVATIVES OF 5 'DEOXICITIDINE - Google Patents

DERIVATIVES OF 5 'DEOXICITIDINE

Info

Publication number
ECSP982518A
ECSP982518A ECSP982518A ECSP982518A EC SP982518 A ECSP982518 A EC SP982518A EC SP982518 A ECSP982518 A EC SP982518A EC SP982518 A ECSP982518 A EC SP982518A
Authority
EC
Ecuador
Prior art keywords
group
atom
substituted
formula
aralkyl
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Nobuo Shimma
Kazuo Hattori
Tohru Ishikawa
Hideo Ishitsuka
Yasunori Kohchi
Nobuhiro Oikawa
Hitomi Suda
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to ECSP982518 priority Critical patent/ECSP982518A/en
Publication of ECSP982518A publication Critical patent/ECSP982518A/en

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Nuevos derivados de 5- desoxicitidina representados por la fórmula (I) (gráfico), en la que R1 es un átomo de hidrógeno o un grupo fácilmente hidrolizable en condiciones fisiológicas; R2 es un átomo de hidrógeno o un grupo -CO-OR4 (en el que R4 es un grupo hidrocarbonado saturado o insaturado, lineal o ramificado, que consiste en uno o quince átomos de carbono, o un grupo de fórmula -(CH2)n -Y (en el que Y es ciclohexilo o fenilo; n es un entero de 0 a 4); R3 es un átomo de hidrógeno, bromo, yodo o ciano, un grupo alquilo C1-4 (que puede estar sustituido con átomo(s) de halógeno, un grupo vinilo o etinilo (que puede estar sustituido con átomo (s) de halógeno, alquilo C1-4, -cicloalquilo, aralquilo, o un anillo aromático que puede tener uno o más heteroátomo (s)), o un grupo aralquilo que puede estar sustituido, para su uso en terapia médica, especialmente en terapia antitumoral.Novel 5-deoxycytidine derivatives represented by formula (I) (graph), wherein R1 is a hydrogen atom or a group easily hydrolyzable under physiological conditions; R2 is a hydrogen atom or a group -CO-OR4 (where R4 is a linear or branched, saturated or unsaturated hydrocarbon group consisting of one or fifteen carbon atoms, or a group of formula - (CH2) n -Y (where Y is cyclohexyl or phenyl; n is an integer from 0 to 4); R3 is a hydrogen, bromine, iodine or cyano atom, a C1-4 alkyl group (which may be substituted with atom (s ) of halogen, a vinyl or ethynyl group (which may be substituted with halogen atom (s), C1-4alkyl, -cycloalkyl, aralkyl, or an aromatic ring which may have one or more heteroatom (s)), or a Aralkyl group which may be substituted, for use in medical therapy, especially in antitumor therapy.

ECSP982518 1998-06-01 1998-06-01 DERIVATIVES OF 5 'DEOXICITIDINE ECSP982518A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ECSP982518 ECSP982518A (en) 1998-06-01 1998-06-01 DERIVATIVES OF 5 'DEOXICITIDINE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ECSP982518 ECSP982518A (en) 1998-06-01 1998-06-01 DERIVATIVES OF 5 'DEOXICITIDINE

Publications (1)

Publication Number Publication Date
ECSP982518A true ECSP982518A (en) 1999-04-13

Family

ID=42043439

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP982518 ECSP982518A (en) 1998-06-01 1998-06-01 DERIVATIVES OF 5 'DEOXICITIDINE

Country Status (1)

Country Link
EC (1) ECSP982518A (en)

Similar Documents

Publication Publication Date Title
CO4940436A1 (en) DERIVATIVES OF 5´-DEOXICITIDINE AND MANUFACTURING PROCESS THEREOF
MX168756B (en) PROCEDURE FOR PREPARING IMIDAZO (4,5-b) PYRIDINE COMPOUNDS
ATE516321T2 (en) COMPOSITIONS CONTAINING FLUOROSUBSTITUTED OLEFINS
ATE111882T1 (en) 2-SUBSTITUTED ALKYL ETHER AND LIQUID CRYSTAL COMPOSITION.
ATE93232T1 (en) BIS(METHYLENEDIOXY)BIPHENYL COMPOUNDS.
KR900016190A (en) 2-phenylpyridine
KR900017974A (en) Liquid Crystal Component Containing Trimethyleneoxy Group
KR860700250A (en) New amidine compounds
DE3676151D1 (en) POLYMERS WITH CONJUGATED DOUBLE BINDINGS.
ES2061487T3 (en) MACROLID COMPOUNDS.
ATE101392T1 (en) FLUORINE-SUBSTITUTED BENZENE DERIVATIVES.
BR8805623A (en) COMPOSITION AND ADDITIVE CONCENTRATE
ES2004141A6 (en) 1,4-Dihydropyridines, processes for their preparation and their use as antithrombotic drugs.
FI870090A0 (en) LAONGKEDJADE ALKYLRESORCINOLPHOSFITER.
ECSP982518A (en) DERIVATIVES OF 5 'DEOXICITIDINE
ES2133153T3 (en) NEW CYCLICAL DEPSIPEPTIDES WITH 18 RING ATOMS, AND THEIR USE FOR THE FIGHT OF ENDOPARASITES.
NO900732D0 (en) ARYLALKYLAMINFORBINDELSER.
DE3872543D1 (en) OPTICALLY ACTIVE 2-SUBSTITUTED PROPYL ETHER AND LIQUID CRYSTAL COMPOSITION.
IT1230595B (en) IMMEDIATE PEROXYCID DERIVATIVES
KR880013901A (en) Thienopyridine Derivatives and Antiulcers
ES2045282T3 (en) A PROCEDURE FOR THE PREPARATION OF 4-SUBSTITUTED ANTHRACICLINONE.
ES468360A1 (en) PROCEDURE FOR THE PREPARATION OF 2- (2 ', 2', 2'-TRIHALOGENETIL) -4-HALOGENCICLOBUTAN-1-ONA.
ATE9892T1 (en) DIBENZOCYCLOHEPTENYLIDENES AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS.
EP0339088A4 (en) DRIVE FLUID.
KR920006273A (en) Chlorophenyl Alkoxyalkyl Compound