ECSP982566A - DERIVATIVES OF 4- BROMINE 4- IODINE PHENYLAMINE ACID BENZHIDROXAMICO - Google Patents
DERIVATIVES OF 4- BROMINE 4- IODINE PHENYLAMINE ACID BENZHIDROXAMICOInfo
- Publication number
- ECSP982566A ECSP982566A ECSP982566A ECSP982566A EC SP982566 A ECSP982566 A EC SP982566A EC SP982566 A ECSP982566 A EC SP982566A EC SP982566 A ECSP982566 A EC SP982566A
- Authority
- EC
- Ecuador
- Prior art keywords
- derivatives
- benzhidroxamico
- bromine
- iodine
- acid
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 title 1
- 229910052794 bromium Inorganic materials 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- VVTCLTONLVZMDI-UHFFFAOYSA-N 2-anilino-n-hydroxybenzamide Chemical class ONC(=O)C1=CC=CC=C1NC1=CC=CC=C1 VVTCLTONLVZMDI-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- -1 alkyl Chemical compound 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 239000002829 mitogen activated protein kinase inhibitor Substances 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 208000037803 restenosis Diseases 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Los derivados del ácido benzhidroxámico fenilamino de la fórmula (gráfico), donde R1, R2, R3, R4, R5 y R6 son hidrógeno o grupos sustituyentes como alquilo, y donde R7 es hidrógeno o un radical orgánico, son inhibidores podentes de MEK y, como tales, son eficaces para el tratamiento del cáncer y otras enfermedades proliferativas como la psoriasis y la restenosis.Derivatives of phenylamino benzhydroxamic acid of the formula (graph), where R1, R2, R3, R4, R5 and R6 are hydrogen or substituent groups such as alkyl, and where R7 is hydrogen or an organic radical, are powerful MEK inhibitors and, As such, they are effective in the treatment of cancer and other proliferative diseases such as psoriasis and restenosis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP982566 ECSP982566A (en) | 1998-06-30 | 1998-06-30 | DERIVATIVES OF 4- BROMINE 4- IODINE PHENYLAMINE ACID BENZHIDROXAMICO |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP982566 ECSP982566A (en) | 1998-06-30 | 1998-06-30 | DERIVATIVES OF 4- BROMINE 4- IODINE PHENYLAMINE ACID BENZHIDROXAMICO |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP982566A true ECSP982566A (en) | 1999-03-02 |
Family
ID=42043486
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP982566 ECSP982566A (en) | 1998-06-30 | 1998-06-30 | DERIVATIVES OF 4- BROMINE 4- IODINE PHENYLAMINE ACID BENZHIDROXAMICO |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP982566A (en) |
-
1998
- 1998-06-30 EC ECSP982566 patent/ECSP982566A/en unknown
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