ECSP982605A - ORAL PHARMACEUTICAL PREPARATION COMPRISING A COMPOUND OF ANTI-ULCER ACTIVITY AND PROCEDURE FOR ITS OBTAINING - Google Patents

ORAL PHARMACEUTICAL PREPARATION COMPRISING A COMPOUND OF ANTI-ULCER ACTIVITY AND PROCEDURE FOR ITS OBTAINING

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Publication number
ECSP982605A
ECSP982605A ECSP982605A ECSP982605A EC SP982605 A ECSP982605 A EC SP982605A EC SP982605 A ECSP982605 A EC SP982605A EC SP982605 A ECSP982605 A EC SP982605A
Authority
EC
Ecuador
Prior art keywords
solution
procedure
excipient
obtaining
compound
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Darder Carlos Picornell
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to ECSP982605 priority Critical patent/ECSP982605A/en
Publication of ECSP982605A publication Critical patent/ECSP982605A/en

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  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Comprende un núcleo inerte, una capa activa soluble o de desintegración rápida en agua obteniendo a partir de una única solución-suspensión acuosa o hidroalcohólica que comprende; un principio activo de actividad antiulcerosa de fórmula I, II, ó III, y por lo menos un excipiente; y una capa de recubrimiento externa gastrorresistente obtenida a partir de una solución que comprende, un polimero de recubrimiento entérico; y por lo menos un excipiente. El procedimiento se lleva a cabo mediante 1) un recubrimiento de los núcleos inertes mediante la nebulización de la única suspensión-solución acuosa o hidroalcohólica; 2) un secado de la capa activa formada durante la nebulización de la etapa anterior; y 3) un recubrimiento de los núcleos cargados mediante la nebulización de una solución que comprende un polímero de recubrimiento entérico con por lo menos un excipiente para obtener una capa de recubrimiento externa gastroresistente.It comprises an inert core, a water-soluble or fast-disintegrating active layer obtained from a single aqueous or hydro-alcoholic suspension-solution comprising; an active ingredient of antiulcer activity of formula I, II, or III, and at least one excipient; and a gastro-resistant outer coating layer obtained from a solution comprising, an enteric coating polymer; and at least one excipient. The procedure is carried out by means of 1) a coating of the inert nuclei by means of the nebulization of the only aqueous-hydroalcoholic suspension-solution; 2) drying the active layer formed during the nebulization of the previous stage; and 3) a coating of the charged nuclei by nebulizing a solution comprising an enteric coating polymer with at least one excipient to obtain a gastroresistant outer coating layer.

ECSP982605 1998-07-29 1998-07-29 ORAL PHARMACEUTICAL PREPARATION COMPRISING A COMPOUND OF ANTI-ULCER ACTIVITY AND PROCEDURE FOR ITS OBTAINING ECSP982605A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ECSP982605 ECSP982605A (en) 1998-07-29 1998-07-29 ORAL PHARMACEUTICAL PREPARATION COMPRISING A COMPOUND OF ANTI-ULCER ACTIVITY AND PROCEDURE FOR ITS OBTAINING

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ECSP982605 ECSP982605A (en) 1998-07-29 1998-07-29 ORAL PHARMACEUTICAL PREPARATION COMPRISING A COMPOUND OF ANTI-ULCER ACTIVITY AND PROCEDURE FOR ITS OBTAINING

Publications (1)

Publication Number Publication Date
ECSP982605A true ECSP982605A (en) 1999-04-21

Family

ID=42043525

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP982605 ECSP982605A (en) 1998-07-29 1998-07-29 ORAL PHARMACEUTICAL PREPARATION COMPRISING A COMPOUND OF ANTI-ULCER ACTIVITY AND PROCEDURE FOR ITS OBTAINING

Country Status (1)

Country Link
EC (1) ECSP982605A (en)

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