ECSP982781A - 5- [4- (-N -METIL-N- (2-PIRIDIL) AMINO) ETOXI) BENSIL) THIAZOLIDINE - 2,4 DIONA MALEIC SALT HYDRATE - Google Patents

5- [4- (-N -METIL-N- (2-PIRIDIL) AMINO) ETOXI) BENSIL) THIAZOLIDINE - 2,4 DIONA MALEIC SALT HYDRATE

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Publication number
ECSP982781A
ECSP982781A ECSP982781A ECSP982781A EC SP982781 A ECSP982781 A EC SP982781A EC SP982781 A ECSP982781 A EC SP982781A EC SP982781 A ECSP982781 A EC SP982781A
Authority
EC
Ecuador
Prior art keywords
provides
thiazolidine
compound
amino
bensil
Prior art date
Application number
Other languages
Spanish (es)
Inventor
Ian Robert Lynch
Michael John Sasse
Bernadette Marie Choudary
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to ECSP982781 priority Critical patent/ECSP982781A/en
Publication of ECSP982781A publication Critical patent/ECSP982781A/en

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Abstract

Un hidrato de la sal de ácido maleico de 5-(4-(2-(N-metil-N-(2-piridil)amino etoxi)bencil) tiazolidina-2,4-diona caracterizado porque: (i) comprende agua en el intervalo de 0,3 a 0,6 equivalentes molares; y (ii) proporciona un espectro infrarrojo que contiene picos a 1757,1331 1290, 1211 y 767 cm-1; y/o (iii) proporciona un espectro Raman que contiene picos a 1758, 1610, 1394 1316 y 1289 cm-1; y/o (iv) proporciona un espectro de resonancia magnética nuclear en estado sólido que contiene desplazamientos quimicos sustancialmente como se indica en la tabla I de esta memoria; y/o (v) proporciona una imagen de disfracción en polvo de rayos X (XRPD) sustancialmente como se indica en la figura IV de esta memoria; un procedimiento para la preparación de un compuesto de este tipo, una composición farmacéutica que contiene dicho compuesto y el uso de un compuesto o composiciones de este tipo en medicina.A hydrate of the maleic acid salt of 5- (4- (2- (N-methyl-N- (2-pyridyl) amino ethoxy) benzyl) thiazolidine-2,4-dione characterized in that: (i) comprises water in the range of 0.3 to 0.6 molar equivalents; and (ii) provides an infrared spectrum containing peaks at 1757, 1331, 1290, 1211, and 767 cm-1; and / or (iii) provides a Raman spectrum containing peaks. a 1758, 1610, 1394 1316 and 1289 cm-1; and / or (iv) provides a solid state nuclear magnetic resonance spectrum containing chemical shifts substantially as indicated in Table I herein; and / or (v ) provides an X-ray powder disfraction image (XRPD) substantially as indicated in Figure IV herein; a procedure for the preparation of such a compound, a pharmaceutical composition containing said compound, and the use of a compound or compositions of this type in medicine.

ECSP982781 1998-12-15 1998-12-15 5- [4- (-N -METIL-N- (2-PIRIDIL) AMINO) ETOXI) BENSIL) THIAZOLIDINE - 2,4 DIONA MALEIC SALT HYDRATE ECSP982781A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ECSP982781 ECSP982781A (en) 1998-12-15 1998-12-15 5- [4- (-N -METIL-N- (2-PIRIDIL) AMINO) ETOXI) BENSIL) THIAZOLIDINE - 2,4 DIONA MALEIC SALT HYDRATE

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ECSP982781 ECSP982781A (en) 1998-12-15 1998-12-15 5- [4- (-N -METIL-N- (2-PIRIDIL) AMINO) ETOXI) BENSIL) THIAZOLIDINE - 2,4 DIONA MALEIC SALT HYDRATE

Publications (1)

Publication Number Publication Date
ECSP982781A true ECSP982781A (en) 1999-05-17

Family

ID=42043700

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP982781 ECSP982781A (en) 1998-12-15 1998-12-15 5- [4- (-N -METIL-N- (2-PIRIDIL) AMINO) ETOXI) BENSIL) THIAZOLIDINE - 2,4 DIONA MALEIC SALT HYDRATE

Country Status (1)

Country Link
EC (1) ECSP982781A (en)

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