ECSP982801A - Composicion para tratar enfermedades respiratorias y de la piel - Google Patents
Composicion para tratar enfermedades respiratorias y de la pielInfo
- Publication number
- ECSP982801A ECSP982801A ECSP982801A ECSP982801A EC SP982801 A ECSP982801 A EC SP982801A EC SP982801 A ECSP982801 A EC SP982801A EC SP982801 A ECSP982801 A EC SP982801A
- Authority
- EC
- Ecuador
- Prior art keywords
- phenyl
- montelukast
- inflammation
- propyl
- hydroxy
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000000241 respiratory effect Effects 0.000 title 1
- 208000017520 skin disease Diseases 0.000 title 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- 206010061218 Inflammation Diseases 0.000 abstract 2
- UCHDWCPVSPXUMX-TZIWLTJVSA-N Montelukast Chemical compound CC(C)(O)C1=CC=CC=C1CC[C@H](C=1C=C(\C=C\C=2N=C3C=C(Cl)C=CC3=CC=2)C=CC=1)SCC1(CC(O)=O)CC1 UCHDWCPVSPXUMX-TZIWLTJVSA-N 0.000 abstract 2
- 208000002193 Pain Diseases 0.000 abstract 2
- 208000003251 Pruritus Diseases 0.000 abstract 2
- 206010039085 Rhinitis allergic Diseases 0.000 abstract 2
- 201000010105 allergic rhinitis Diseases 0.000 abstract 2
- 208000006673 asthma Diseases 0.000 abstract 2
- 230000004054 inflammatory process Effects 0.000 abstract 2
- 229960005127 montelukast Drugs 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- SFOVDSLXFUGAIV-UHFFFAOYSA-N 1-[(4-fluorophenyl)methyl]-n-piperidin-4-ylbenzimidazol-2-amine Chemical compound C1=CC(F)=CC=C1CN1C2=CC=CC=C2N=C1NC1CCNCC1 SFOVDSLXFUGAIV-UHFFFAOYSA-N 0.000 abstract 1
- BAWMMJAUVBLLEE-UHFFFAOYSA-N 2-[2-[4-[bis(4-fluorophenyl)methyl]piperazin-1-yl]ethoxy]acetic acid Chemical compound C1CN(CCOCC(=O)O)CCN1C(C=1C=CC(F)=CC=1)C1=CC=C(F)C=C1 BAWMMJAUVBLLEE-UHFFFAOYSA-N 0.000 abstract 1
- 125000004938 5-pyridyl group Chemical group N1=CC=CC(=C1)* 0.000 abstract 1
- -1 6,7-difluoro 2-quinolinyl Chemical group 0.000 abstract 1
- FWEOQOXTVHGIFQ-UHFFFAOYSA-N 8-anilinonaphthalene-1-sulfonic acid Chemical compound C=12C(S(=O)(=O)O)=CC=CC2=CC=CC=1NC1=CC=CC=C1 FWEOQOXTVHGIFQ-UHFFFAOYSA-N 0.000 abstract 1
- ZKLPARSLTMPFCP-UHFFFAOYSA-N Cetirizine Chemical compound C1CN(CCOCC(=O)O)CCN1C(C=1C=CC(Cl)=CC=1)C1=CC=CC=C1 ZKLPARSLTMPFCP-UHFFFAOYSA-N 0.000 abstract 1
- 206010011224 Cough Diseases 0.000 abstract 1
- 208000000059 Dyspnea Diseases 0.000 abstract 1
- 206010013975 Dyspnoeas Diseases 0.000 abstract 1
- 206010019233 Headaches Diseases 0.000 abstract 1
- 206010020751 Hypersensitivity Diseases 0.000 abstract 1
- 206010028735 Nasal congestion Diseases 0.000 abstract 1
- 208000005141 Otitis Diseases 0.000 abstract 1
- 206010037884 Rash pruritic Diseases 0.000 abstract 1
- 208000036071 Rhinorrhea Diseases 0.000 abstract 1
- 206010039101 Rhinorrhoea Diseases 0.000 abstract 1
- 201000009961 allergic asthma Diseases 0.000 abstract 1
- 208000026935 allergic disease Diseases 0.000 abstract 1
- 230000007815 allergy Effects 0.000 abstract 1
- GXDALQBWZGODGZ-UHFFFAOYSA-N astemizole Chemical compound C1=CC(OC)=CC=C1CCN1CCC(NC=2N(C3=CC=CC=C3N=2)CC=2C=CC(F)=CC=2)CC1 GXDALQBWZGODGZ-UHFFFAOYSA-N 0.000 abstract 1
- 229960001803 cetirizine Drugs 0.000 abstract 1
- 208000019258 ear infection Diseases 0.000 abstract 1
- 210000005069 ears Anatomy 0.000 abstract 1
- 229960001971 ebastine Drugs 0.000 abstract 1
- MJJALKDDGIKVBE-UHFFFAOYSA-N ebastine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(=O)CCCN1CCC(OC(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 MJJALKDDGIKVBE-UHFFFAOYSA-N 0.000 abstract 1
- 229950003420 efletirizine Drugs 0.000 abstract 1
- 229960003449 epinastine Drugs 0.000 abstract 1
- WHWZLSFABNNENI-UHFFFAOYSA-N epinastine Chemical compound C1C2=CC=CC=C2C2CN=C(N)N2C2=CC=CC=C21 WHWZLSFABNNENI-UHFFFAOYSA-N 0.000 abstract 1
- 229960003592 fexofenadine Drugs 0.000 abstract 1
- RWTNPBWLLIMQHL-UHFFFAOYSA-N fexofenadine Chemical compound C1=CC(C(C)(C(O)=O)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 RWTNPBWLLIMQHL-UHFFFAOYSA-N 0.000 abstract 1
- 231100000869 headache Toxicity 0.000 abstract 1
- 230000007803 itching Effects 0.000 abstract 1
- 239000003199 leukotriene receptor blocking agent Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 210000004877 mucosa Anatomy 0.000 abstract 1
- 201000009240 nasopharyngitis Diseases 0.000 abstract 1
- 230000036407 pain Effects 0.000 abstract 1
- 210000003254 palate Anatomy 0.000 abstract 1
- 230000002085 persistent effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 229960004583 pranlukast Drugs 0.000 abstract 1
- UAJUXJSXCLUTNU-UHFFFAOYSA-N pranlukast Chemical compound C=1C=C(OCCCCC=2C=CC=CC=2)C=CC=1C(=O)NC(C=1)=CC=C(C(C=2)=O)C=1OC=2C=1N=NNN=1 UAJUXJSXCLUTNU-UHFFFAOYSA-N 0.000 abstract 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 208000013220 shortness of breath Diseases 0.000 abstract 1
- 201000009890 sinusitis Diseases 0.000 abstract 1
- 206010041232 sneezing Diseases 0.000 abstract 1
- 125000000446 sulfanediyl group Chemical group *S* 0.000 abstract 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Una composición farmacéutica útil para el tratamiento del estornudo, picazón y goteo de la nariz, congestión nasal, enrojecimiento de los ojos, lagrimeo, picazón en los oidos o paladar, brevedad de la respiración, inflamación de la mucosa bronquil, volumen expiatorio forzado en un segundo (FEV), reducido, tos, erupción picazón en la piel, dolores de cabeza y dolores persistentes y dolores asociados con la rinitis alérgica, rinitis alérgica permanente, resfrios comunes, otitis, sinusitis, alergia, asma, asma alérgico y/o inflamación, en un organismo de mamífero que necesita este tratamiento. La composición comprende: i) una cantidad efectiva de al menos un antagonista de leucotrieno seleccionado de g) montelukast h) ácido 1-(((R)(3-(2-(6,7-difluoro 2-quinolinil)etenl)fenil)-2-(2-hidroxi 2-propil)fenil) metilcilopropanoacético; i) ácido 1-(((1(R)-3(3-2-(2,3-diclorotiene(3,2)piridin-5-il)-(E)-etenil)fenil-2-(2-(1hidroxi-1-metil-fenil)propil)tio)metil)ciclopropanoacético;j) pranlukast; o k) zafirtukast, o l) ácido (2-((2--ter-butil -2tiazoli-)-5benzofuranil)oximetil)fenil) acético, o su sal farmacéuticamente aceptable, mezclado con ii) una cantidad efectiva de al menos una anthhistamina que es desacarboetoxiloratidina, cetirizina, fexofenadina, ebastina, astemizol, norastemizol, epinastina, efletirizina o su sal farmacéuticamente aceptable. g) montelukast.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP982801 ECSP982801A (es) | 1998-12-21 | 1998-12-21 | Composicion para tratar enfermedades respiratorias y de la piel |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP982801 ECSP982801A (es) | 1998-12-21 | 1998-12-21 | Composicion para tratar enfermedades respiratorias y de la piel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP982801A true ECSP982801A (es) | 1999-05-17 |
Family
ID=42043718
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP982801 ECSP982801A (es) | 1998-12-21 | 1998-12-21 | Composicion para tratar enfermedades respiratorias y de la piel |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP982801A (es) |
-
1998
- 1998-12-21 EC ECSP982801 patent/ECSP982801A/es unknown
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