ECSP992858A - ANTIBODIES AGAINST HUMAN CD40 - Google Patents
ANTIBODIES AGAINST HUMAN CD40Info
- Publication number
- ECSP992858A ECSP992858A ECSP992858A ECSP992858A EC SP992858 A ECSP992858 A EC SP992858A EC SP992858 A ECSP992858 A EC SP992858A EC SP992858 A ECSP992858 A EC SP992858A
- Authority
- EC
- Ecuador
- Prior art keywords
- antibodies
- antibodies against
- against human
- human
- applicants
- Prior art date
Links
- 101150013553 CD40 gene Proteins 0.000 title abstract 4
- 102100040245 Tumor necrosis factor receptor superfamily member 5 Human genes 0.000 title abstract 4
- 102100032937 CD40 ligand Human genes 0.000 abstract 1
- 101000759376 Escherichia phage Mu Tail sheath protein Proteins 0.000 abstract 1
- 101000868215 Homo sapiens CD40 ligand Proteins 0.000 abstract 1
- 210000001744 T-lymphocyte Anatomy 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 206010003246 arthritis Diseases 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 230000028996 humoral immune response Effects 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 238000002054 transplantation Methods 0.000 abstract 1
Landscapes
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Los solicitantes han descubierto nuevos anticuerpos CD40 anti-humanos quiméricos y humanizados que bloquean la interacción entre gp39 y CD40. Los anticuerpos CD40 de la presente invención son efectivos en la modulación de respuestas inmunes humorales contra antígenos que dependen de la célula T, artritis introducida por colágeno, y transplante de piel, y también son útiles por sus propiedades anti-inflamatorias.Applicants have discovered new chimeric and humanized anti-human CD40 antibodies that block the interaction between gp39 and CD40. The CD40 antibodies of the present invention are effective in modulating humoral immune responses against T-cell dependent antigens, collagen-introduced arthritis, and skin transplantation, and are also useful for their anti-inflammatory properties.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP992858 ECSP992858A (en) | 1999-02-12 | 1999-02-12 | ANTIBODIES AGAINST HUMAN CD40 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP992858 ECSP992858A (en) | 1999-02-12 | 1999-02-12 | ANTIBODIES AGAINST HUMAN CD40 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP992858A true ECSP992858A (en) | 2000-09-22 |
Family
ID=42043847
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP992858 ECSP992858A (en) | 1999-02-12 | 1999-02-12 | ANTIBODIES AGAINST HUMAN CD40 |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP992858A (en) |
-
1999
- 1999-02-12 EC ECSP992858 patent/ECSP992858A/en unknown
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