ECSP992874A - HETERO-CYCLIC COMPOUNDS AS ROTHAMASE ENZYME INHIBITORS - Google Patents

HETERO-CYCLIC COMPOUNDS AS ROTHAMASE ENZYME INHIBITORS

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Publication number
ECSP992874A
ECSP992874A ECSP992874A ECSP992874A EC SP992874 A ECSP992874 A EC SP992874A EC SP992874 A ECSP992874 A EC SP992874A EC SP992874 A ECSP992874 A EC SP992874A
Authority
EC
Ecuador
Prior art keywords
enzyme inhibitors
rothamase
hetero
cyclic compounds
compounds
Prior art date
Application number
Other languages
Spanish (es)
Inventor
David John Bull
Robert John Maguire
Michael John Palmer
Martin James Wythes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Priority to ECSP992874 priority Critical patent/ECSP992874A/en
Publication of ECSP992874A publication Critical patent/ECSP992874A/en

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Los compuestos de la fórmula: (gráfico), en la que R1, Y, W, A y R2 son como se han definido anteriormente, son inhibidores de enzimas rotamas, en particular, FKBP-12 y FKBP-52. Por lo tanto, los compuestos moderan la regeneración y extensión neuronal y pueden usarse para el tratamiento de trastornos neurológicos producidos por enfermedades neurodegenerativas y lesiones nerviosas.Compounds of the formula: (graph), where R1, Y, W, A and R2 are as defined above, are rotama enzyme inhibitors, in particular FKBP-12 and FKBP-52. Therefore, the compounds moderate neuronal regeneration and extension and can be used for the treatment of neurological disorders caused by neurodegenerative diseases and nerve injuries.

ECSP992874 1999-03-01 1999-03-01 HETERO-CYCLIC COMPOUNDS AS ROTHAMASE ENZYME INHIBITORS ECSP992874A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ECSP992874 ECSP992874A (en) 1999-03-01 1999-03-01 HETERO-CYCLIC COMPOUNDS AS ROTHAMASE ENZYME INHIBITORS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ECSP992874 ECSP992874A (en) 1999-03-01 1999-03-01 HETERO-CYCLIC COMPOUNDS AS ROTHAMASE ENZYME INHIBITORS

Publications (1)

Publication Number Publication Date
ECSP992874A true ECSP992874A (en) 1999-06-11

Family

ID=42043862

Family Applications (1)

Application Number Title Priority Date Filing Date
ECSP992874 ECSP992874A (en) 1999-03-01 1999-03-01 HETERO-CYCLIC COMPOUNDS AS ROTHAMASE ENZYME INHIBITORS

Country Status (1)

Country Link
EC (1) ECSP992874A (en)

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