ECSP992879A - PIRAZOLOPIRIMIDINAS AND PIRAZOLOTRIAZINAS - Google Patents
PIRAZOLOPIRIMIDINAS AND PIRAZOLOTRIAZINASInfo
- Publication number
- ECSP992879A ECSP992879A ECSP992879A ECSP992879A EC SP992879 A ECSP992879 A EC SP992879A EC SP992879 A ECSP992879 A EC SP992879A EC SP992879 A ECSP992879 A EC SP992879A
- Authority
- EC
- Ecuador
- Prior art keywords
- disease
- disorders
- depressions
- pirazolotriazinas
- pirazolopirimidinas
- Prior art date
Links
- APXRHPDHORGIEB-UHFFFAOYSA-N 1H-pyrazolo[4,3-d]pyrimidine Chemical class N1=CN=C2C=NNC2=C1 APXRHPDHORGIEB-UHFFFAOYSA-N 0.000 abstract 1
- 108091005435 5-HT6 receptors Proteins 0.000 abstract 1
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 208000020925 Bipolar disease Diseases 0.000 abstract 1
- 208000020401 Depressive disease Diseases 0.000 abstract 1
- 208000023105 Huntington disease Diseases 0.000 abstract 1
- 208000026139 Memory disease Diseases 0.000 abstract 1
- PEYVWBGHBCDXRT-UHFFFAOYSA-N N1=NNC2=CN=NC2=C1 Chemical class N1=NNC2=CN=NC2=C1 PEYVWBGHBCDXRT-UHFFFAOYSA-N 0.000 abstract 1
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000025966 Neurological disease Diseases 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 208000028017 Psychotic disease Diseases 0.000 abstract 1
- 206010002026 amyotrophic lateral sclerosis Diseases 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 201000000980 schizophrenia Diseases 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
La presente invención se refiere a pirazolopirimidinas y pirazolotriazinas de la fórmula general (gráfico), y sus sales farmacéuticamente aceptables. Sorprendentemente, estos compuestos tienen una afinidad selectiva para los receptores de la 5HT-6. Son convenientemente adecuados para el tratamiento y prevención de trastornos nerviosos centrales tales como por ejemplo, psicosis, esquizofrenia, depresiones maniaticas, depresiones, trastornos neurológicos, trastornos de la memoria, enfermedad de Parkinson, esclerosis lateral amiotrófica, enfermedad de Alzheimer y corea de Huntington.The present invention relates to pyrazolopyrimidines and pyrazolotriazines of the general formula (graph), and their pharmaceutically acceptable salts. Surprisingly, these compounds have a selective affinity for 5HT-6 receptors. They are conveniently suitable for the treatment and prevention of central nervous disorders such as, for example, psychosis, schizophrenia, manic depressions, depressions, neurological disorders, memory disorders, Parkinson's disease, amyotrophic lateral sclerosis, Alzheimer's disease and Huntington's chorea.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP992879 ECSP992879A (en) | 1999-03-09 | 1999-03-09 | PIRAZOLOPIRIMIDINAS AND PIRAZOLOTRIAZINAS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP992879 ECSP992879A (en) | 1999-03-09 | 1999-03-09 | PIRAZOLOPIRIMIDINAS AND PIRAZOLOTRIAZINAS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP992879A true ECSP992879A (en) | 2000-11-24 |
Family
ID=42043867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP992879 ECSP992879A (en) | 1999-03-09 | 1999-03-09 | PIRAZOLOPIRIMIDINAS AND PIRAZOLOTRIAZINAS |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP992879A (en) |
-
1999
- 1999-03-09 EC ECSP992879 patent/ECSP992879A/en unknown
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