ECSP992904A - CALCILITICAL COMPOUNDS - Google Patents
CALCILITICAL COMPOUNDSInfo
- Publication number
- ECSP992904A ECSP992904A ECSP992904A ECSP992904A EC SP992904 A ECSP992904 A EC SP992904A EC SP992904 A ECSP992904 A EC SP992904A EC SP992904 A ECSP992904 A EC SP992904A
- Authority
- EC
- Ecuador
- Prior art keywords
- receptor antagonists
- fracture healing
- calcium receptor
- disease
- calcilitical
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- 208000010392 Bone Fractures Diseases 0.000 abstract 2
- 229940123613 Calcium receptor antagonist Drugs 0.000 abstract 2
- 206010017076 Fracture Diseases 0.000 abstract 2
- 230000035876 healing Effects 0.000 abstract 2
- 208000037147 Hypercalcaemia Diseases 0.000 abstract 1
- 208000000038 Hypoparathyroidism Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000010191 Osteitis Deformans Diseases 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- 208000027868 Paget disease Diseases 0.000 abstract 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 230000000148 hypercalcaemia Effects 0.000 abstract 1
- 208000030915 hypercalcemia disease Diseases 0.000 abstract 1
- 230000036210 malignancy Effects 0.000 abstract 1
- 208000027202 mammary Paget disease Diseases 0.000 abstract 1
- 230000004079 mineral homeostasis Effects 0.000 abstract 1
- 239000008203 oral pharmaceutical composition Substances 0.000 abstract 1
- 201000008482 osteoarthritis Diseases 0.000 abstract 1
- 201000008968 osteosarcoma Diseases 0.000 abstract 1
- 208000028169 periodontal disease Diseases 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 206010039073 rheumatoid arthritis Diseases 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
El presente invento comprende nuevos antagonistas del receptor de calcio, representados más adelante por la fórmula (I), y a su uso como antagonistas del receptor de calcio en el tratamiento de una diversidad de enfermedades asociadas con una anormal homeostásis ósea o mineral, incluyendo, pero no limitándose a, hipoparatiroidismo, osteosarcoma, enfermedad periodontal, curación de fracturas, osteoartritis, artritis reumatoide, enfermedad de Paget, hipercalcemia humoral asociada con malignidad y curación de fracturas, y y osteoporosis. El caracterizado por el echo de que los gránulos resultantes poseen un tamaño en el rango variando de 0,150 a 0,355mm. En otro aspecto, la invención se refiere a composiciones farmacéuticas orales conteniendo un antibiótico en la forma de un polvo granulado-revestido.The present invention encompasses novel calcium receptor antagonists, represented below by formula (I), and their use as calcium receptor antagonists in the treatment of a variety of diseases associated with abnormal bone or mineral homeostasis, including, but not limited to, hypoparathyroidism, osteosarcoma, periodontal disease, fracture healing, osteoarthritis, rheumatoid arthritis, Paget's disease, humoral hypercalcemia associated with malignancy and fracture healing, and and osteoporosis. The one characterized by the fact that the resulting granules have a size in the range varying from 0.150 to 0.355mm. In another aspect, the invention relates to oral pharmaceutical compositions containing an antibiotic in the form of a granulated-coated powder.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP992904 ECSP992904A (en) | 1999-04-05 | 1999-04-05 | CALCILITICAL COMPOUNDS |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP992904 ECSP992904A (en) | 1999-04-05 | 1999-04-05 | CALCILITICAL COMPOUNDS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP992904A true ECSP992904A (en) | 1999-09-09 |
Family
ID=42043893
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP992904 ECSP992904A (en) | 1999-04-05 | 1999-04-05 | CALCILITICAL COMPOUNDS |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP992904A (en) |
-
1999
- 1999-04-05 EC ECSP992904 patent/ECSP992904A/en unknown
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